| Gene Information | |
|---|---|
| Official Symbol | CGA |
| NCBI Gene Identifier | NCBI: 1081 |
| Gene Name | glycoprotein hormones, alpha polypeptide |
| UniProt Symbol | P01215 |
| ENSEMBL ID | ENSG00000135346 |
| Protein Class | peptide hormone |
| KEGG ID | hsa:1081 |
| KEGG Pathway | Neuroactive ligand-receptor interaction, cAMP signaling pathway, Autoimmune thyroid disease, Prolactin signaling pathway, Thyroid hormone synthesis, Regulation of lipolysis in adipocytes, GnRH secretion, GnRH signaling pathway, Ovarian steroidogenesis |
| Ontology Type | Accession | Ontology Term |
|---|---|---|
| Biological process | GO:0007165, GO:0034641, GO:0051604 | signal transduction, cellular nitrogen compound metabolic process, protein maturation |
| Molecular function | - | - |
| Cellular component | GO:0005623, GO:0005622, GO:0043226, GO:0005737, GO:0005576, GO:0005615, GO:0032991, GO:0005794 | cell, intracellular, organelle, cytoplasm, extracellular region, extracellular space, protein-containing complex, Golgi apparatus |
| Literature identifier | Biospecimen | Technique used to ascertain differential expression | Regulation | Fold level change | p-value | Control group | Ectopic group | Maternal factors | Expression Type |
|---|---|---|---|---|---|---|---|---|---|
| PMID: 2050251 | Serum | Enzyme immunoassay | Down | - | <0.01 | Intrauterine pregnancy | Ectopic pregnancy | - | Proteome |
| PMID: 2469696 | Serum | Radioimmunoassay | Down | - | <0.01 | Intrauterine pregnancy | Ectopic pregnancy | - | Proteome |
| PMID: 6188479 | Plasma | Radioimmunoassay | Down | - | <0.001 | Intrauterine pregnancy | Ectopic pregnancy | Gestation > 40 days | Proteome |
| PMID: 7504682 | Serum | Fluoroimmunoassay | Down | - | <0.05 | Intrauterine pregnancy | Ectopic pregnancy | IVF patients | Proteome |
| PMID: 11750960 | Serum | Enzyme immunoassay | Down | - | <0.0001 | Intrauterine pregnancy | Ectopic pregnancy | - | Proteome |
| PMID: 18249366 | Serum | Immunometric assays | Down | - | <0.001 | Intrauterine pregnancy | Ectopic pregnancy | IVF patients | Proteome |
| PMID: 21142075 | Serum | LC-MS/MS | Down | -4.91 | <0.001 | Intrauterine pregnancy | Ectopic pregnancy | - | Proteome |
| PMID: 21858178 | Endometrium | Microarray | Up | 5.4369693 | <0.05 | Intrauterine pregnancy with similar decidualization | Ectopic pregnancy | - | Transcriptome |
| PMID: 22395025 | Serum | Protein assays | Down | - | <0.001 | Intrauterine pregnancy | Ectopic pregnancy | - | Proteome |
EPEK is a comprehensive knowledgebase of expression data relevant to ectopic pregnancy in humans that has been collated and curated from the published scientific literature. We are not liable for any inaccuracies or omissions of any expression data or published scientific literature pertaining to ectopic pregnancy, and users are recommended to use their own discretion while utilizing our resource. The primary goal of developing this resource is to facilitate basic research on ectopic pregnancy in humans, and it does not necessarily reflect the views or objectives of our employers or funders.