Gene: fms related receptor tyrosine kinase 1


Gene Information
Official SymbolFLT1
NCBI Gene IdentifierNCBI: 2321
Gene Namefms related receptor tyrosine kinase 1
UniProt SymbolP17948
ENSEMBL IDENSG00000102755
Protein Classtransmembrane signal receptor
KEGG ID hsa:2321
KEGG PathwayPI3K-Akt signaling pathway, Focal adhesion, Rheumatoid arthritis, Rap1 signaling pathway, MAPK signaling pathway, HIF-1 signaling pathway, Ras signaling pathway, Transcriptional misregulation in cancer, Calcium signaling pathway


Ontologies
Ontology TypeAccessionOntology Term
Biological processGO:0007165, GO:0048856, GO:0002376, GO:0030154, GO:0040011, GO:0048870, GO:0006464, GO:0048646, GO:0009790signal transduction, anatomical structure development, immune system process, cell differentiation, locomotion, cell motility, cellular protein modification process, anatomical structure formation involved in morphogenesis, embryo development
Molecular functionGO:0043167, GO:0016301ion binding, kinase activity
Cellular componentGO:0005623, GO:0005622, GO:0043226, GO:0005737, GO:0005576, GO:0005615, GO:0005886, GO:0032991, GO:0031410, GO:0005856, GO:0005768cell, intracellular, organelle, cytoplasm, extracellular region, extracellular space, plasma membrane, protein-containing complex, cytoplasmic vesicle, cytoskeleton, endosome

Information on gene expression associated with ectopic pregnancy
Literature identifierBiospecimenTechnique used to ascertain differential expressionRegulationFold level changep-valueControl groupEctopic groupMaternal factorsExpression Type
PMID: 15374715OviductqRT PCRUp-<0.01Non-implantationImplantation site-Transcriptome
PMID: 21715541SerumELISADown-<0.001Intrauterine pregnancyEctopic pregnancy-Proteome
PMID: 24699433SerumElectrochemiluminescence assayDown-<0.001Missed abortionEctopic pregnancy-Proteome

DISCLAIMER

EPEK is a comprehensive knowledgebase of expression data relevant to ectopic pregnancy in humans that has been collated and curated from the published scientific literature. We are not liable for any inaccuracies or omissions of any expression data or published scientific literature pertaining to ectopic pregnancy, and users are recommended to use their own discretion while utilizing our resource. The primary goal of developing this resource is to facilitate basic research on ectopic pregnancy in humans, and it does not necessarily reflect the views or objectives of our employers or funders.