EPEK | Ectopic Pregnancy Knowledgebase

Gene: major histocompatibility complex, class II, DR alpha

Gene Information
Official Symbol	HLA-DRA
NCBI Gene Identifier	NCBI: 3122
Gene Name	major histocompatibility complex, class II, DR alpha
UniProt Symbol	P01903
ENSEMBL ID	ENSG00000204287
Protein Class	major histocompatibility complex protein
KEGG ID	hsa:3122
KEGG Pathway	Influenza A, Rheumatoid arthritis, Tuberculosis, Th17 cell differentiation, Hematopoietic cell lineage, Toxoplasmosis, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Herpes simplex virus 1 infection, Inflammatory bowel disease, Leishmaniasis, Intestinal immune network for IgA production, Phagosome, Staphylococcus aureus infection, Graft-versus-host disease, Cell adhesion molecules, Type I diabetes mellitus, Asthma, Autoimmune thyroid disease, Allograft rejection, Systemic lupus erythematosus, Antigen processing and presentation, Viral myocarditis, Th1 and Th2 cell differentiation

Ontologies

Ontology Type	Accession	Ontology Term
Biological process	GO:0007165 , GO:0006950 , GO:0002376 , GO:0022607 , GO:0065003 , GO:0044403 , GO:0050877	signal transduction , response to stress , immune system process , cellular component assembly , protein-containing complex assembly , symbiotic process , nervous system process
Molecular function	-	-
Cellular component	GO:0005623 , GO:0005622 , GO:0043226 , GO:0005737 , GO:0005576 , GO:0005615 , GO:0005886 , GO:0032991 , GO:0031410 , GO:0005783 , GO:0005794 , GO:0005768 , GO:0005764 , GO:0005773	cell , intracellular , organelle , cytoplasm , extracellular region , extracellular space , plasma membrane , protein-containing complex , cytoplasmic vesicle , endoplasmic reticulum , Golgi apparatus , endosome , lysosome , vacuole

Information on gene expression associated with ectopic pregnancy

Literature identifier	Biospecimen	Technique used to ascertain differential expression	Regulation	Fold level change	p-value	Control group	Ectopic group	Maternal factors	Expression Type
PMID: 18591649	Endometrium	Microarray	Up	4.446	0.000012	Mid-secretory phase	Ectopic pregnancy	-	Transcriptome

DISCLAIMER

EPEK is a comprehensive knowledgebase of expression data relevant to ectopic pregnancy in humans that has been collated and curated from the published scientific literature. We are not liable for any inaccuracies or omissions of any expression data or published scientific literature pertaining to ectopic pregnancy, and users are recommended to use their own discretion while utilizing our resource. The primary goal of developing this resource is to facilitate basic research on ectopic pregnancy in humans, and it does not necessarily reflect the views or objectives of our employers or funders.