| Gene Information | |
|---|---|
| Official Symbol | IL6R |
| NCBI Gene Identifier | NCBI: 3570 |
| Gene Name | interleukin 6 receptor |
| UniProt Symbol | P08887 |
| ENSEMBL ID | ENSG00000160712 |
| Protein Class | transmembrane signal receptor |
| KEGG ID | hsa:3570 |
| KEGG Pathway | Cytokine-cytokine receptor interaction, Pathways in cancer, PI3K-Akt signaling pathway, Human cytomegalovirus infection, JAK-STAT signaling pathway, Viral protein interaction with cytokine and cytokine receptor, HIF-1 signaling pathway, Th17 cell differentiation, Coronavirus disease, Hematopoietic cell lineage, EGFR tyrosine kinase inhibitor resistance, Non-alcoholic fatty liver disease |
| Ontology Type | Accession | Ontology Term |
|---|---|---|
| Biological process | GO:0007165, GO:0048856, GO:0006950, GO:0002376, GO:0040011, GO:0048870, GO:0008219 | signal transduction, anatomical structure development, response to stress, immune system process, locomotion, cell motility, cell death |
| Molecular function | GO:0019899 | enzyme binding |
| Cellular component | GO:0005623, GO:0005576, GO:0005615, GO:0005886, GO:0032991 | cell, extracellular region, extracellular space, plasma membrane, protein-containing complex |
| Literature identifier | Biospecimen | Technique used to ascertain differential expression | Regulation | Fold level change | p-value | Control group | Ectopic group | Maternal factors | Expression Type |
|---|---|---|---|---|---|---|---|---|---|
| PMID: 27511901 | Fallopian tube | qPCR | Up | - | 0.0001 | Non-pregnant | Ectopic pregnancy | - | Transcriptome |
| PMID: 27511901 | Fallopian tube | Immunohistochemistry | Up | - | 0.003 | Non-pregnant | Ectopic pregnancy | - | Proteome |
EPEK is a comprehensive knowledgebase of expression data relevant to ectopic pregnancy in humans that has been collated and curated from the published scientific literature. We are not liable for any inaccuracies or omissions of any expression data or published scientific literature pertaining to ectopic pregnancy, and users are recommended to use their own discretion while utilizing our resource. The primary goal of developing this resource is to facilitate basic research on ectopic pregnancy in humans, and it does not necessarily reflect the views or objectives of our employers or funders.