| Gene Information | |
|---|---|
| Official Symbol | LIF |
| NCBI Gene Identifier | NCBI: 3976 |
| Gene Name | LIF interleukin 6 family cytokine |
| UniProt Symbol | P15018 |
| ENSEMBL ID | ENSG00000128342 |
| Protein Class | cytokine |
| KEGG ID | hsa:3976 |
| KEGG Pathway | Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Signaling pathways regulating pluripotency of stem cells, TNF signaling pathway |
| Ontology Type | Accession | Ontology Term |
|---|---|---|
| Biological process | GO:0007165, GO:0048856, GO:0002376, GO:0030154, GO:0000003, GO:0006464, GO:0009790 | signal transduction, anatomical structure development, immune system process, cell differentiation, reproduction, cellular protein modification process, embryo development |
| Molecular function | - | - |
| Cellular component | GO:0005623, GO:0005622, GO:0005737, GO:0005576, GO:0005615, GO:0005829 | cell, intracellular, cytoplasm, extracellular region, extracellular space, cytosol |
| Literature identifier | Biospecimen | Technique used to ascertain differential expression | Regulation | Fold level change | p-value | Control group | Ectopic group | Maternal factors | Expression Type |
|---|---|---|---|---|---|---|---|---|---|
| PMID: 8987949 | Isthmic tubal segment | Northern blotting analysis | Up | (Four fold increase) | 0.008 | Non-pregnant | Ectopic pregnancy | - | Transcriptome |
| PMID: 15167855 | Endometrium | qRT PCR | Up | - | Non-pregnant | Ectopic pregnancy | Luteal phase | Transcriptome | |
| PMID: 27511901 | Fallopian tube | qPCR | Up | - | 0.0002 | Non-pregnant | Ectopic pregnancy | - | Transcriptome |
EPEK is a comprehensive knowledgebase of expression data relevant to ectopic pregnancy in humans that has been collated and curated from the published scientific literature. We are not liable for any inaccuracies or omissions of any expression data or published scientific literature pertaining to ectopic pregnancy, and users are recommended to use their own discretion while utilizing our resource. The primary goal of developing this resource is to facilitate basic research on ectopic pregnancy in humans, and it does not necessarily reflect the views or objectives of our employers or funders.