| Gene Information | |
|---|---|
| Official Symbol | PAPPA |
| NCBI Gene Identifier | NCBI: 5069 |
| Gene Name | pappalysin 1 |
| UniProt Symbol | Q13219 |
| ENSEMBL ID | ENSG00000182752 |
| Protein Class | - |
| KEGG ID | hsa:5069 |
| Ontology Type | Accession | Ontology Term |
|---|---|---|
| Biological process | GO:0000003 | reproduction |
| Molecular function | GO:0043167, GO:0008233 | ion binding, peptidase activity |
| Cellular component | GO:0005576, GO:0005615 | extracellular region, extracellular space |
| Literature identifier | Biospecimen | Technique used to ascertain differential expression | Regulation | Fold level change | p-value | Control group | Ectopic group | Maternal factors | Expression Type |
|---|---|---|---|---|---|---|---|---|---|
| PMID: 2445774 | Serum | Radioimmunoassay | Down | - | <0.001 | Intrauterine pregnancy | Ectopic pregnancy | - | Proteome |
| PMID: 6188479 | Plasma | Radioimmunoassay | Down | - | <0.01 | Intrauterine pregnancy | Ectopic pregnancy | Gestation of 41-50 days | Proteome |
| PMID: 7504682 | Serum | Radioimmunoassay | Down | - | <0.05 | Intrauterine pregnancy | Ectopic pregnancy | IVF patients | Proteome |
| PMID: 11750960 | Serum | Enzyme immunoassay | Down | - | <0.0001 | Intrauterine pregnancy | Ectopic pregnancy | - | Proteome |
| PMID: 21142075 | Serum | LC-MS/MS | Down | -16.67 | <0.001 | Intrauterine pregnancy | Ectopic pregnancy | - | Proteome |
| PMID: 21343760 | Serum | ELISA | Down | - | <0.001 | Intrauterine pregnancy | Ectopic pregnancy | - | Proteome |
| PMID: 34093757 | Serum | ELISA | Down | - | <0.001 | Intrauterine pregnancy | Ectopic pregnancy | - | Proteome |
EPEK is a comprehensive knowledgebase of expression data relevant to ectopic pregnancy in humans that has been collated and curated from the published scientific literature. We are not liable for any inaccuracies or omissions of any expression data or published scientific literature pertaining to ectopic pregnancy, and users are recommended to use their own discretion while utilizing our resource. The primary goal of developing this resource is to facilitate basic research on ectopic pregnancy in humans, and it does not necessarily reflect the views or objectives of our employers or funders.