Gene: prostaglandin-endoperoxide synthase 2


Gene Information
Official SymbolPTGS2
NCBI Gene IdentifierNCBI: 5743
Gene Nameprostaglandin-endoperoxide synthase 2
UniProt SymbolP35354
ENSEMBL IDENSG00000073756
Protein Classoxygenase
KEGG ID hsa:5743
KEGG PathwayMetabolic pathways, Pathways in cancer, Pathways of neurodegeneration, Human cytomegalovirus infection, Human papillomavirus infection, MicroRNAs in cancer, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Leishmaniasis, IL-17 signaling pathway, Alzheimer disease, Small cell lung cancer, TNF signaling pathway, Retrograde endocannabinoid signaling, VEGF signaling pathway, Oxytocin signaling pathway, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Serotonergic synapse, Regulation of lipolysis in adipocytes, Arachidonic acid metabolism, Ovarian steroidogenesis


Ontologies
Ontology TypeAccessionOntology Term
Biological processGO:0007165, GO:0048856, GO:0006950, GO:0030154, GO:0000003, GO:0009058, GO:0034641, GO:0044281, GO:0048646, GO:0006629, GO:0003013, GO:0050877, GO:0051186, GO:0007568signal transduction, anatomical structure development, response to stress, cell differentiation, reproduction, biosynthetic process, cellular nitrogen compound metabolic process, small molecule metabolic process, anatomical structure formation involved in morphogenesis, lipid metabolic process, circulatory system process, nervous system process, cofactor metabolic process, aging
Molecular functionGO:0043167, GO:0019899, GO:0016491ion binding, enzyme binding, oxidoreductase activity
Cellular componentGO:0005623, GO:0005622, GO:0043226, GO:0005737, GO:0005886, GO:0032991, GO:0005783cell, intracellular, organelle, cytoplasm, plasma membrane, protein-containing complex, endoplasmic reticulum

Information on gene expression associated with ectopic pregnancy
Literature identifierBiospecimenTechnique used to ascertain differential expressionRegulationFold level changep-valueControl groupEctopic groupMaternal factorsExpression Type
PMID: 18591649EndometriumMicroarrayUp4.9740.00521Mid-secretory phaseEctopic pregnancy-Transcriptome

DISCLAIMER

EPEK is a comprehensive knowledgebase of expression data relevant to ectopic pregnancy in humans that has been collated and curated from the published scientific literature. We are not liable for any inaccuracies or omissions of any expression data or published scientific literature pertaining to ectopic pregnancy, and users are recommended to use their own discretion while utilizing our resource. The primary goal of developing this resource is to facilitate basic research on ectopic pregnancy in humans, and it does not necessarily reflect the views or objectives of our employers or funders.