EPEK | Ectopic Pregnancy Knowledgebase

Gene: BCL2 apoptosis regulator

Gene Information
Official Symbol	BCL2
NCBI Gene Identifier	NCBI: 596
Gene Name	BCL2 apoptosis regulator
UniProt Symbol	P10415
ENSEMBL ID	ENSG00000171791
Protein Class	-
KEGG ID	hsa:596
KEGG Pathway	Pathways in cancer, PI3K-Akt signaling pathway, Pathways of neurodegeneration, Focal adhesion, Tuberculosis, Chemical carcinogenesis, Fluid shear stress and atherosclerosis, JAK-STAT signaling pathway, Salmonella infection, Lipid and atherosclerosis, HIF-1 signaling pathway, MicroRNAs in cancer, Shigellosis, Toxoplasmosis, Epstein-Barr virus infection, Herpes simplex virus 1 infection, Amyotrophic lateral sclerosis, Parathyroid hormone synthesis, secretion and action, NF-kappa B signaling pathway, AGE-RAGE signaling pathway in diabetic complications, EGFR tyrosine kinase inhibitor resistance, NOD-like receptor signaling pathway, Hepatitis B, Gastric cancer, Human immunodeficiency virus 1 infection, Measles, Small cell lung cancer, Necroptosis, Prostate cancer, Adrenergic signaling in cardiomyocytes, Colorectal cancer, Estrogen signaling pathway, Platinum drug resistance, Sphingolipid signaling pathway, Apoptosis, Endocrine resistance, Neurotrophin signaling pathway, Autophagy, Cholinergic synapse, p53 signaling pathway, Protein processing in endoplasmic reticulum, Hedgehog signaling pathway, Apoptosis

Ontologies

Ontology Type	Accession	Ontology Term
Biological process	GO:0007165 , GO:0048856 , GO:0006950 , GO:0002376 , GO:0006810 , GO:0030154 , GO:0042592 , GO:0000003 , GO:0006464 , GO:0022607 , GO:0007155 , GO:0000902 , GO:0008219 , GO:0007010 , GO:0061024 , GO:0008283 , GO:0055085 , GO:0040007 , GO:0007568 , GO:0034330 , GO:0007005 , GO:0043473 , GO:0019748	signal transduction , anatomical structure development , response to stress , immune system process , transport , cell differentiation , homeostatic process , reproduction , cellular protein modification process , cellular component assembly , cell adhesion , cell morphogenesis , cell death , cytoskeleton organization , membrane organization , cell population proliferation , transmembrane transport , growth , aging , cell junction organization , mitochondrion organization , pigmentation , secondary metabolic process
Molecular function	GO:0019899 , GO:0003677 , GO:0022857 , GO:0008134	enzyme binding , DNA binding , transmembrane transporter activity , transcription factor binding
Cellular component	GO:0005623 , GO:0005622 , GO:0043226 , GO:0005737 , GO:0005634 , GO:0032991 , GO:0005829 , GO:0005783 , GO:0005654 , GO:0005739 , GO:0005635	cell , intracellular , organelle , cytoplasm , nucleus , protein-containing complex , cytosol , endoplasmic reticulum , nucleoplasm , mitochondrion , nuclear envelope

Information on gene expression associated with ectopic pregnancy

Literature identifier	Biospecimen	Technique used to ascertain differential expression	Regulation	Fold level change	p-value	Control group	Ectopic group	Maternal factors	Expression Type
PMID: 24586750	Fallopian tube	qRT PCR	Down	(1.5 fold)	<0.05	Non-smokers	-	Smokers	Transcriptome

DISCLAIMER

EPEK is a comprehensive knowledgebase of expression data relevant to ectopic pregnancy in humans that has been collated and curated from the published scientific literature. We are not liable for any inaccuracies or omissions of any expression data or published scientific literature pertaining to ectopic pregnancy, and users are recommended to use their own discretion while utilizing our resource. The primary goal of developing this resource is to facilitate basic research on ectopic pregnancy in humans, and it does not necessarily reflect the views or objectives of our employers or funders.