Gene: toll like receptor 4


Gene Information
Official SymbolTLR4
NCBI Gene IdentifierNCBI: 7099
Gene Nametoll like receptor 4
UniProt SymbolO00206
ENSEMBL IDENSG00000136869
Protein Classtransmembrane signal receptor
KEGG ID hsa:7099
KEGG PathwayPI3K-Akt signaling pathway, Influenza A, Rheumatoid arthritis, Tuberculosis, Salmonella infection, Lipid and atherosclerosis, Proteoglycans in cancer, HIF-1 signaling pathway, Coronavirus disease, Amoebiasis, Shigellosis, Toxoplasmosis, Inflammatory bowel disease, Malaria, NF-kappa B signaling pathway, Leishmaniasis, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, Hepatitis B, Human immunodeficiency virus 1 infection, Chagas disease, Measles, Yersinia infection, Pathogenic Escherichia coli infection, Phagosome, Necroptosis, Alcoholic liver disease, Legionellosis, Pertussis, PD-L1 expression and PD-1 checkpoint pathway in cancer, Neutrophil extracellular trap formation


Ontologies
Ontology TypeAccessionOntology Term
Biological processGO:0007165, GO:0048856, GO:0006950, GO:0002376, GO:0006810, GO:0030154, GO:0042592, GO:0016192, GO:0006464, GO:0008219, GO:0015031, GO:0008283signal transduction, anatomical structure development, response to stress, immune system process, transport, cell differentiation, homeostatic process, vesicle-mediated transport, cellular protein modification process, cell death, protein transport, cell population proliferation
Molecular functionGO:0008289lipid binding
Cellular componentGO:0005623, GO:0005622, GO:0043226, GO:0005737, GO:0005886, GO:0032991, GO:0031410, GO:0005768cell, intracellular, organelle, cytoplasm, plasma membrane, protein-containing complex, cytoplasmic vesicle, endosome

Information on gene expression associated with ectopic pregnancy
Literature identifierBiospecimenTechnique used to ascertain differential expressionRegulationFold level changep-valueControl groupEctopic groupMaternal factorsExpression Type
PMID: 27793374Fallopian tubeqRT PCRUp-<0.001Non-pregnantEctopic pregnancy-Transcriptome
PMID: 27793374Fallopian tubeImmunohistochemistryUp-0.007Non-pregnantEctopic pregnancy-Proteome

DISCLAIMER

EPEK is a comprehensive knowledgebase of expression data relevant to ectopic pregnancy in humans that has been collated and curated from the published scientific literature. We are not liable for any inaccuracies or omissions of any expression data or published scientific literature pertaining to ectopic pregnancy, and users are recommended to use their own discretion while utilizing our resource. The primary goal of developing this resource is to facilitate basic research on ectopic pregnancy in humans, and it does not necessarily reflect the views or objectives of our employers or funders.