| Gene Information | |
|---|---|
| Official Symbol | VHL |
| NCBI Gene Identifier | NCBI: 7428 |
| Gene Name | von Hippel-Lindau tumor suppressor |
| UniProt Symbol | P40337 |
| ENSEMBL ID | ENSG00000134086 |
| Protein Class | ubiquitin-protein ligase |
| KEGG ID | hsa:7428 |
| KEGG Pathway | Pathways in cancer, HIF-1 signaling pathway, Ubiquitin mediated proteolysis, Renal cell carcinoma |
| Ontology Type | Accession | Ontology Term |
|---|---|---|
| Biological process | GO:0048856, GO:0006950, GO:0006464, GO:0000902 | anatomical structure development, response to stress, cellular protein modification process, cell morphogenesis |
| Molecular function | GO:0019899, GO:0008134 | enzyme binding, transcription factor binding |
| Cellular component | GO:0005623, GO:0005622, GO:0043226, GO:0005737, GO:0005634, GO:0032991, GO:0005829, GO:0005783, GO:0005654, GO:0005739 | cell, intracellular, organelle, cytoplasm, nucleus, protein-containing complex, cytosol, endoplasmic reticulum, nucleoplasm, mitochondrion |
| Literature identifier | Biospecimen | Technique used to ascertain differential expression | Regulation | Fold level change | p-value | Control group | Ectopic group | Maternal factors | Expression Type |
|---|---|---|---|---|---|---|---|---|---|
| PMID: 22714833 | Fallopian tube | qRT PCR | Up | - | <0.01 | Non-pregnant | Implantation site | Mid-secretory phase | Transcriptome |
| PMID: 22714833 | Fallopian tube | Immunostaining | Up | - | <0.01 | Non-pregnant | Implantation site | Mid-secretory phase | Proteome |
EPEK is a comprehensive knowledgebase of expression data relevant to ectopic pregnancy in humans that has been collated and curated from the published scientific literature. We are not liable for any inaccuracies or omissions of any expression data or published scientific literature pertaining to ectopic pregnancy, and users are recommended to use their own discretion while utilizing our resource. The primary goal of developing this resource is to facilitate basic research on ectopic pregnancy in humans, and it does not necessarily reflect the views or objectives of our employers or funders.