Heavy Metal-specific Toxicity Networks
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Chemicals List

CAS PubChemID Chemical Name Database ClassyFire Chemical Classification
Kingdom Superclass Class
CAS:7790-78-5 CID:24978551 Cadmium chloride hydrate (1:2.5) ToxCast Inorganic compounds Mixed metal/non-metal compounds Transition metal salts
CAS:7790-79-6 CID:24634 Cadmium fluoride CTD Inorganic compounds Mixed metal/non-metal compounds Transition metal salts
CAS:7790-80-9 CID:24635 Cadmium iodide CTD, ECOTOX Inorganic compounds Mixed metal/non-metal compounds Transition metal salts
CAS:7790-85-4 CID:4985693 Cadmium;dihydroxy(dioxo)tungsten CTD Inorganic compounds Mixed metal/non-metal compounds Transition metal oxoanionic compounds
CAS:7789-42-6 CID:24609 Cadmium bromide (cdbr2) ECOTOX Inorganic compounds Mixed metal/non-metal compounds Transition metal salts
CAS:10022-68-1 CID:56924536 Cadmium nitrate tetrahydrate ECOTOX Inorganic compounds Mixed metal/non-metal compounds Transition metal oxoanionic compounds
CAS:14378-39-3 CID:121233901 Cadmium, isotope of mass 106 CTD Inorganic compounds Homogeneous metal compounds Homogeneous transition metal compounds
- CID:25184604 Cadmium-112 CTD Inorganic compounds Homogeneous metal compounds Homogeneous transition metal compounds
CAS:14336-64-2 CID:25087163 Cadmium-111 CTD Inorganic compounds Homogeneous metal compounds Homogeneous transition metal compounds
CAS:1306-25-8 CID:91501 Cadmium telluride CTD Inorganic compounds Mixed metal/non-metal compounds Metalloid salts
CAS:1306-23-6 CID:14783 Cadmium sulfide CTD, ECOTOX Inorganic compounds Mixed metal/non-metal compounds Transition metal organides
CAS:1306-19-0 CID:14782 Cadmium oxide CTD, ECOTOX, ToxCast Inorganic compounds Mixed metal/non-metal compounds Transition metal organides
CAS:12014-28-7 CID:159393 Cadmium phosphide (cd3p2) CTD Inorganic compounds Mixed metal/non-metal compounds Miscellaneous mixed metal/non-metals
CAS:10325-94-7 CID:25154 Cadmium nitrate CTD, DEDuCT, ECOTOX, ToxCast Inorganic compounds Mixed metal/non-metal compounds Transition metal oxoanionic compounds
CAS:10124-36-4 CID:24962 Cadmium sulfate CTD, ECOTOX Inorganic compounds Mixed metal/non-metal compounds Transition metal oxoanionic compounds
CAS:10108-64-2 CID:24947 Cadmium chloride AOP-Wiki, CTD, DEDuCT, ECOTOX, NeurotoxKb, ToxCast Inorganic compounds Mixed metal/non-metal compounds Transition metal salts
CAS:7440-43-9 CID:23973 Cadmium AOP-Wiki, CTD, DEDuCT, ECOTOX, NeurotoxKb Inorganic compounds Homogeneous metal compounds Homogeneous transition metal compounds
- CID:46182348 Cadmium-110 CTD Inorganic compounds Homogeneous metal compounds Homogeneous transition metal compounds

Stressor-AOP Networks

Level of Relevance Number of AOPs Link to network Cytoscape file
Level 1 62 Visualize Network Download
Level 2 135 Visualize Network Download
Level 3 37 Visualize Network Download
Level 5 84 Visualize Network Download


Level 5 AOP networks with coverage score > 0.4

Undirected AOP Network

Directed AOP Network

Stressor-species networks

Using Toxicity (LC50/EC50) Data

CAS Number of ECOTOX Species Groups Number of Species
CAS:10325-94-7 11 74
CAS:10108-64-2 10 506
CAS:10124-36-4 9 95
CAS:7440-43-9 8 117
CAS:7790-80-9 2 2
CAS:1306-19-0 2 2
CAS:1306-23-6 2 2
CAS:10022-68-1 1 1


Using Toxicity (NOEC) Data

CAS Number of ECOTOX Species Groups Number of Species
CAS:10108-64-2 13 221
CAS:10124-36-4 8 23
CAS:7440-43-9 8 46
CAS:10325-94-7 6 20


Using Bioconcentration Factor (BCF) Data

CAS Number of ECOTOX Species Groups Number of Species
CAS:10108-64-2 10 96
CAS:7440-43-9 7 39
CAS:10325-94-7 6 23
CAS:10124-36-4 3 11

Species Sensitivity Distributions (SSDs) based on acute toxicity data

SSDs for inorganic compounds of Cadmium

CAS Chemical Name Number of ECOTOX Species Groups Number of Species Best-fit Model SSD Toolbox Results ssdtools Results Raw Data
HC05 HC05 LCL HC05 UCL SSD Plot HC05 HC05 LCL HC05 UCL SSD Plot
CAS:7440-43-9 Cadmium 8 113 Weibull 0.0058 0.001 0.0155 View Plot 0.0058 0.0019 0.0177 View Plot Download Data
CAS:10108-64-2 Cadmium chloride 10 494 Log-Logistic 0.0181 0.0123 0.0271 View Plot 0.0180 0.0122 0.0263 View Plot Download Data
CAS:10124-36-4 Cadmium sulfate 9 93 Log-Normal 0.0172 0.0073 0.0361 View Plot 0.0172 0.0079 0.0392 View Plot Download Data
CAS:10325-94-7 Cadmium nitrate 11 71 Log-Normal 0.0219 0.0096 0.0559 View Plot 0.0219 0.0091 0.0563 View Plot Download Data


Model Averaged Values

CAS Chemical Name Number of ECOTOX Species Groups Number of Species SSD Toolbox Results ssdtools Results
HC05 HC05 Standard Error HC05 HC05 Standard Error SSD Plot
CAS:7440-43-9 Cadmium 8 113 0.0066 0.0043 0.0066 0.005 View Plot
CAS:10108-64-2 Cadmium chloride 10 494 0.0185 0.004 0.0184 0.0039 View Plot
CAS:10124-36-4 Cadmium sulfate 9 93 0.0165 0.0092 0.0165 0.0091 View Plot
CAS:10325-94-7 Cadmium nitrate 11 71 0.0203 0.0106 0.0203 0.012 View Plot


Toxicity-normalized SSD (SSDn) for Cadmium

Number of ECOTOX Species Groups Number of Species Best-fit Model SSD Toolbox Results ssdtools Results Raw Data
HC05 HC05 LCL HC05 UCL SSD Plot HC05 HC05 LCL HC05 UCL SSD Plot
12 628 Log-Logistic 0.6214 0.4443 0.8886 View Plot 0.6169 0.4359 0.8779 View Plot Download Data


Model Averaged Values

Number of ECOTOX Species Groups Number of Species SSD Toolbox Results ssdtools Results
HC05 HC05 Standard Error HC05 HC05 Standard Error SSD Plot
12 628 0.6089 0.1218 0.6049 0.1204 View Plot


Species Sensitivity Distributions (SSDs) based on chronic toxicity data

SSDs for inorganic compounds of Cadmium

CAS Chemical Name Number of ECOTOX Species Groups Number of Species Best-fit Model SSD Toolbox Results ssdtools Results Raw Data
HC05 HC05 LCL HC05 UCL SSD Plot HC05 HC05 LCL HC05 UCL SSD Plot
CAS:7440-43-9 Cadmium 8 45 Log-Logistic 0.000092 0.000014 0.000593 View Plot 0.000092 0.000014 0.000607 View Plot Download Data
CAS:10108-64-2 Cadmium chloride 12 210 BurrIII 0.0019 0.001 0.0032 View Plot 0.001819 0.001053 0.003177 View Plot Download Data
CAS:10124-36-4 Cadmium sulfate 7 2 Log-Normal 0.000548 0.000128 0.0031 View Plot 0.0005481 0.002949 0.0392 View Plot Download Data
CAS:10325-94-7 Cadmium nitrate 6 19 Weibull 0.0013 0.000002 0.0149 View Plot 0.001283 0.000081 0.021204 View Plot Download Data


Model Averaged Values

CAS Chemical Name Number of ECOTOX Species Groups Number of Species SSD Toolbox Results ssdtools Results
HC05 HC05 Standard Error HC05 HC05 Standard Error SSD Plot
CAS:7440-43-9 Cadmium 8 45 0.000110 0.000102 0.000111 0.000187 View Plot
CAS:10108-64-2 Cadmium chloride 12 210 0.001717 0.000599 0.001563 0.00049 View Plot
CAS:10124-36-4 Cadmium sulfate 7 22 0.000565 0.000479 0.000565 0.000741 View Plot
CAS:10325-94-7 Cadmium nitrate 6 19 0.001855 0.006879 0.001855 0.006857 View Plot


Toxicity-normalized SSD (SSDn) for Cadmium

Number of ECOTOX Species Groups Number of Species Best-fit Model SSD Toolbox Results ssdtools Results Raw Data
HC05 HC05 LCL HC05 UCL SSD Plot HC05 HC05 LCL HC05 UCL SSD Plot
12 250 Log-Logistic 0.1487 0.0771 0.2818 View Plot 0.137145 0.070507 0.2686 View Plot Download Data


Model Averaged Values

Number of ECOTOX Species Groups Number of Species SSD Toolbox Results ssdtools Results
HC05 HC05 Standard Error HC05 HC05 Standard Error SSD Plot
12 250 0.16008 0.058171 0.146987 0.057462 View Plot

Source-Environmental media network



DISCLAIMER

The authors are not liable for any inaccuracies or omissions of chemicals or their associations with Adverse Outcome Pathways (AOPs) and different species on this website. Users are advised to exercise their own discretion when assessing the weight of evidence for heavy metals and AOP associations. HC05 values and other statistics derived from Species Sensitivity Distributions (SSDs) should be interpreted cautiously and independently verified. The sole purpose of this website is to support future basic research, and it does not necessarily reflect the views or objectives of our employers or funders.

For further details, contact:

Areejit Samal
Computational Biology Group,
The Institute of Mathematical Sciences (IMSc),
Chennai, India.

The Institute of Mathematical Sciences (IMSc), Chennai is a constituent institution of the Homi Bhabha National Institute (HBNI), Mumbai, India.

The Institute of Mathematical Sciences (IMSc) | Areejit Samal


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