ReCAnt | Resource on Chemicals Used in Aquaculture and Their Ecotoxicity

Niclosamide

Effects reported: Genetics Biochemistry Enzyme(s) Growth

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ⓘ Table glossary

Reference	Experiment type	Cell / tissue	Test organism	Lifestage	Administration	Administered dose	Significant dose	Trend	Measurement	Effect
PMID:38137017	In vivo	-	Mylopharyngodon piceus	-	-	50 µg/L	50 µg/L	Decreased	Acetyl-CoA carboxylase 1 mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	50 µg/L	50 µg/L	Decreased	Acyl-coenzyme A oxidase 1 mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Adenosine triphosphate	Biochemistry
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Calcium Magnesium adenosine triphosphatase	Enzyme(s)
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Catalase activity	Enzyme(s)
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Cholesterol	Biochemistry
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Claudin 3 mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Claudin 4 mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Claudin 8 mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	FAS mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Glucose	Biochemistry
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Glucose-6-phosphatase mRNA	Enzyme(s)
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Glycerol-3-phosphate acyltransferase 1 mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Glycogen	Biochemistry
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Kelch-like ECH-associated protein 1 mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	50 µg/L	50 µg/L	Decreased	Kelch-like ECH-associated protein 1a mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Kelch-like ECH-associated protein 1b mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Occludin mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Sodium potassium ATPase	Enzyme(s)
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Sterol regulatory element binding protein 1 mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Superoxide dismutase (SOD) enzyme activity	Enzyme(s)
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	Tight junction protein ZO-2 mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	50 µg/L	50 µg/L	Decreased	Triglycerides	Biochemistry
	In vivo	-	Mylopharyngodon piceus	-	-	50 µg/L	50 µg/L	Decreased	Weight	Growth
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Decreased	ZO3 mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Increased	Acetyl-CoA synthetase	Enzyme(s)
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Increased	Acyl-coenzyme A oxidase 1 mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Increased	Carnitine palmitoyltransferase 1a, liver mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Increased	Catalase activity	Enzyme(s)
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Increased	Fat/cd36 mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Increased	Glucokinase mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Increased	Glucose-6-phosphatase mRNA	Enzyme(s)
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Increased	Lactate dehydrogenase	Enzyme(s)
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Increased	Lactic acid	Biochemistry
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Increased	Malondialdehyde	Biochemistry
	In vivo	-	Mylopharyngodon piceus	-	-	50 µg/L	50 µg/L	Increased	Nuclear Factor erythroid 2-related factor mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	10.0-50.0 µg/L	10.0-50.0 µg/L	Increased	Pyruvate kinase mRNA	Genetics
	In vivo	-	Mylopharyngodon piceus	-	-	10 µg/L	10 µg/L	Increased	Solute carrier family 27 (fatty acid transporter), member 1 mRNA	Genetics

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Glossary ×

ReferencePubMed ID of research paper

Experimental TypeIn vivo or in vitro

Cell / TissueIf in vitro, cells derived from aquaculture-relevant species

Cell / TissueIf in vitro, tissues obtained from aquaculture-relevant species

Cell / TissueIf in vivo, left blank

Test OrganismAquaculture-relevant species tested for toxic effect

LifestageLifestage of the test organism if mentioned in the reference

AdministrationRoute by which the chemical enters the test organism or treatment method

Administered dose rangeDifferent doses of chemicals tested in this study

Significant dose rangeSignificant result(s) at specific doses

Trend Direction of effect over time

Measurement Parameter used to quantify the effect

Effect Overall observed biological outcome or toxicological effect

Niclosamide

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