Sulfamethoxazole

Sulfamethoxazole



Effects reported: Enzyme(s) Genetics Biochemistry
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ⓘ Table glossary
Table glossary
ReferencePubMed ID of research paper
Experimental TypeIn vivo or in vitro
Cell / TissueIf in vitro, cells derived from aquaculture-relevant species
Cell / TissueIf in vitro, tissues obtained from aquaculture-relevant species
Cell / TissueIf in vivo, left blank
Test OrganismAquaculture-relevant species tested for toxic effect
LifestageLifestage of the test organism if mentioned in the reference
AdministrationRoute by which the chemical enters the test organism or treatment method
Administered dose rangeDifferent doses of chemicals tested in this study
Significant dose rangeSignificant result(s) at specific doses
Trend Direction of effect over time
Measurement Parameter used to quantify the effect
Effect Overall observed biological outcome or toxicological effect
Reference Experiment type Cell / tissue Test organism Lifestage Administration Administered dose Significant dose Trend Measurement Effect
PMID:35032680 In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Decreased Acetylcholinesterase (AChE) activity Enzyme(s)
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Decreased Apoptosis regulator Bcl-2 mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Decreased B cell lymphoma/leukemia 2 Biochemistry
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Decreased Claudin 1 mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Decreased Claudin 3 mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Decreased Glutathione (reduced glutathione) Biochemistry
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Decreased Kelch-like ECH-associated protein 1 Biochemistry
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Decreased Kelch-like ECH-associated protein 1 mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Decreased Nuclear factor-kappa B Biochemistry
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Decreased Occludin Biochemistry
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Decreased Occludin mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Decreased Sequestosome 1 Biochemistry
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Decreased Sequestosome 1 mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Decreased Tight junction protein 1 Biochemistry
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Decreased Tight junction protein 1 mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Decreased Tight junction protein ZO-2 mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased 8-hydroxy-2'-deoxyguanosine Enzyme(s)
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Alpha-induced tumor necrosis factor mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Autophagy protein 5 Biochemistry
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Autophagy protein 5 mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Bcl-2 associated X protein Biochemistry
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Bcl-2 associated X protein to B cell lymphoma/leukemia 2 ratio Biochemistry
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Beclin-1 Biochemistry
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Beclin-1 mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Caspase 3 Enzyme(s)
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Caspase 9 Enzyme(s)
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Caspase-3 mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Caspase-9 mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Heme oxygenase Enzyme(s)
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Heme oxygenase mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Inhibitor of nuclear factor kappa-B Biochemistry
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Interleukin 6 mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Interleukin 8 mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Interleukin-1 beta mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased LC3-II mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Malondialdehyde Biochemistry
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased NAD(P)H-quinone oxidoreductase subunit 1 Enzyme(s)
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Nqo1 mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Nuclear Factor E2 Related Factor 2 Biochemistry
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Nuclear Factor erythroid 2-related factor mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Nuclear factor-kappa B Biochemistry
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Ratio of LC3-II mRNA to LC3-I mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Ratio of LC3-II to LC3-I Biochemistry
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Ratio of bax mRNA to Bcl-2 mRNA Genetics
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased Superoxide dismutase (SOD) enzyme activity Enzyme(s)
In vivo - Ctenopharyngodon idella - Water treatment 0.3
µg/L		 0.3
µg/L		 Increased bax mRNA Genetics
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Glossary ×
ReferencePubMed ID of research paper
Experimental TypeIn vivo or in vitro
Cell / TissueIf in vitro, cells derived from aquaculture-relevant species
Cell / TissueIf in vitro, tissues obtained from aquaculture-relevant species
Cell / TissueIf in vivo, left blank
Test OrganismAquaculture-relevant species tested for toxic effect
LifestageLifestage of the test organism if mentioned in the reference
AdministrationRoute by which the chemical enters the test organism or treatment method
Administered dose rangeDifferent doses of chemicals tested in this study
Significant dose rangeSignificant result(s) at specific doses
Trend Direction of effect over time
Measurement Parameter used to quantify the effect
Effect Overall observed biological outcome or toxicological effect
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ReCAnt is a database of chemicals used in aquaculture and their ecotoxic effects, compiled from published literature. The authors are not liable for any inaccuracies or omissions of any chemicals in this resource. Importantly, our sole goal to build this resource on chemicals used in aquaculture is to enable future basic research on this topic, and it does not necessarily reflect the views or objectives of our employers or funders.