Fenvalerate

Fenvalerate



Predicted Absorption properties
PropertyToolInterpretationProbability/Value
Caco-2 permeabilitypkCSMHigh1.062 cm/s
Human Intestinal AbsorptionpkCSMHigh92.875 %
SwissADMEHigh-
Log Kp (Skin permeation)pkCSMHigh-2.692 cm/h
SwissADME--4.46 cm/s
P-glycoprotein substratepkCSMNo-
SwissADMEYes-
vNNNo-
P-glycoprotein inhibitorvNNNo-
P-glycoprotein inhibitor IpkCSMYes-
P-glycoprotein inhibitor IIpkCSMYes-
Predicted Distribution properties
PropertyToolInterpretationProbability/Value
Blood Brain BarrierpkCSMModerate-0.253 logBB
SwissADMENo-
vNNNo Prediction-
CNS permeabilitypkCSMYes-1.583 logPS
Fraction unbound in humanpkCSM-0
Steady state volume of distribution (VDss)pkCSMModerate0.165 L/Kg
Predicted Metabolism properties
PropertyToolInterpretationProbability/Value
CYP1A2 inhibitorpkCSMYes-
SwissADMENo-
vNNNo Prediction-
CYP2C19 inhibitorpkCSMYes-
SwissADMEYes-
vNNNo Prediction-
CYP2C9 inhibitorpkCSMYes-
SwissADMEYes-
vNNNo Prediction-
CYP2D6 inhibitorpkCSMNo-
SwissADMEYes-
vNNNo Prediction-
CYP2D6 substratepkCSMNo-
CYP3A4 inhibitorpkCSMYes-
SwissADMEYes-
vNNNo Prediction-
CYP3A4 substratepkCSMYes-
Human Liver Microsomal (HLM) stability assayvNNNo Prediction-
Predicted Excretion properties
PropertyToolInterpretationProbability/Value
Renal OCT2 substratepkCSMNo-
Total clearancepkCSM--0.154 ml/min/kg
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DISCLAIMER

ExHuMId is a knowledgebase compiled through manual curation of published scientific literature wherein environmental contaminants were detected in human milk samples across India. We are not responsible for any errors in published scientific articles from where the human milk exposome specific to India was compiled. We are also not responsible for any omission of published scientific articles containing information on human milk exposome specific to India. Importantly, our primary goal to build this resource was to enable future research on human exposome studies specific to India. Hence, the views expressed in this work are solely based on our scientific understanding of the topic, and they do not necessarily reflect the views or policies of our employers or funders.



DISCLAIMER

ExHuMId is a knowledgebase compiled through manual curation of published scientific literature wherein environmental contaminants were detected in human milk samples across India. We are not responsible for any errors in published scientific articles from where the human milk exposome specific to India was compiled. We are also not responsible for any omission of published scientific articles containing information on human milk exposome specific to India. Importantly, our primary goal to build this resource was to enable future research on human exposome studies specific to India. Hence, the views expressed in this work are solely based on our scientific understanding of the topic, and they do not necessarily reflect the views or policies of our employers or funders.