CB-170

CB-170



Predicted Absorption properties
PropertyToolInterpretationProbability/Value
Caco-2 permeabilitypkCSMNANA cm/s
Human Intestinal AbsorptionpkCSMNANA %
SwissADMELow-
Log Kp (Skin permeation)pkCSMNANA cm/h
SwissADME--3.07 cm/s
P-glycoprotein substratepkCSMNA-
SwissADMEYes-
vNNNo Prediction-
P-glycoprotein inhibitorvNNNo Prediction-
P-glycoprotein inhibitor IpkCSMNA-
P-glycoprotein inhibitor IIpkCSMNA-
Predicted Distribution properties
PropertyToolInterpretationProbability/Value
Blood Brain BarrierpkCSMNANA logBB
SwissADMENo-
vNNNo Prediction-
CNS permeabilitypkCSMNANA logPS
Fraction unbound in humanpkCSM-NA
Steady state volume of distribution (VDss)pkCSMNANA L/Kg
Predicted Metabolism properties
PropertyToolInterpretationProbability/Value
CYP1A2 inhibitorpkCSMNA-
SwissADMENo-
vNNNo Prediction-
CYP2C19 inhibitorpkCSMNA-
SwissADMENo-
vNNNo Prediction-
CYP2C9 inhibitorpkCSMNA-
SwissADMEYes-
vNNNo Prediction-
CYP2D6 inhibitorpkCSMNA-
SwissADMENo-
vNNNo Prediction-
CYP2D6 substratepkCSMNA-
CYP3A4 inhibitorpkCSMNA-
SwissADMENo-
vNNNo-
CYP3A4 substratepkCSMNA-
Human Liver Microsomal (HLM) stability assayvNNNo Prediction-
Predicted Excretion properties
PropertyToolInterpretationProbability/Value
Renal OCT2 substratepkCSMNA-
Total clearancepkCSM-NA ml/min/kg
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DISCLAIMER

ExHuMId is a knowledgebase compiled through manual curation of published scientific literature wherein environmental contaminants were detected in human milk samples across India. We are not responsible for any errors in published scientific articles from where the human milk exposome specific to India was compiled. We are also not responsible for any omission of published scientific articles containing information on human milk exposome specific to India. Importantly, our primary goal to build this resource was to enable future research on human exposome studies specific to India. Hence, the views expressed in this work are solely based on our scientific understanding of the topic, and they do not necessarily reflect the views or policies of our employers or funders.



DISCLAIMER

ExHuMId is a knowledgebase compiled through manual curation of published scientific literature wherein environmental contaminants were detected in human milk samples across India. We are not responsible for any errors in published scientific articles from where the human milk exposome specific to India was compiled. We are also not responsible for any omission of published scientific articles containing information on human milk exposome specific to India. Importantly, our primary goal to build this resource was to enable future research on human exposome studies specific to India. Hence, the views expressed in this work are solely based on our scientific understanding of the topic, and they do not necessarily reflect the views or policies of our employers or funders.