Chlorpyrifos

Chlorpyrifos



Chemical nameGene identifierToxCast assay component endpoint name
ChlorpyrifosARACEA_AR_antagonist_80hr
ChlorpyrifosAHRATG_Ahr_CIS_up
ChlorpyrifosFOSATG_AP_1_CIS_up
ChlorpyrifosJUNATG_AP_1_CIS_up
ChlorpyrifosSMAD1ATG_BRE_CIS_up
ChlorpyrifosNR1H2ATG_DR4_LXR_CIS_dn
ChlorpyrifosNR1H3ATG_DR4_LXR_CIS_dn
ChlorpyrifosE2F1ATG_E2F_CIS_dn
ChlorpyrifosESR1ATG_ERa_TRANS_up
ChlorpyrifosESR1ATG_ERE_CIS_up
ChlorpyrifosETS1ATG_Ets_CIS_dn
ChlorpyrifosGATA1ATG_GATA_CIS_dn
ChlorpyrifosGLI1ATG_GLI_CIS_up
ChlorpyrifosNR1H4ATG_IR1_CIS_dn
ChlorpyrifosIRF1ATG_ISRE_CIS_dn
ChlorpyrifosMTF1ATG_MRE_CIS_up
ChlorpyrifosNFIAATG_NFI_CIS_up
ChlorpyrifosNRF1ATG_NRF1_CIS_up
ChlorpyrifosNFE2L2ATG_NRF2_ARE_CIS_up
ChlorpyrifosPOU2F1ATG_Oct_MLP_CIS_up
ChlorpyrifosPPARGATG_PPARg_TRANS_up
ChlorpyrifosNR1I2ATG_PXRE_CIS_up
ChlorpyrifosNR1I2ATG_PXR_TRANS_up
ChlorpyrifosRXRBATG_RXRb_TRANS_up
ChlorpyrifosSP1ATG_Sp1_CIS_up
ChlorpyrifosSREBF1ATG_SREBP_CIS_up
ChlorpyrifosVDRATG_VDRE_CIS_up
ChlorpyrifosXBP1ATG_Xbp1_CIS_up
ChlorpyrifosSELEBSK_3C_Eselectin_down
ChlorpyrifosHLA-DRABSK_3C_HLADR_down
ChlorpyrifosCXCL8BSK_3C_IL8_down
ChlorpyrifosCCL2BSK_3C_MCP1_down
ChlorpyrifosPLAURBSK_3C_uPAR_down
ChlorpyrifosVCAM1BSK_3C_VCAM1_down
ChlorpyrifosCCL26BSK_4H_Eotaxin3_down
ChlorpyrifosSELPBSK_4H_Pselectin_down
ChlorpyrifosVCAM1BSK_4H_VCAM1_down
ChlorpyrifosHLA-DRABSK_BE3C_HLADR_down
ChlorpyrifosLDLRBSK_CASM3C_LDLR_up
ChlorpyrifosTHBDBSK_CASM3C_Thrombomodulin_up
ChlorpyrifosCOL3A1BSK_hDFCGF_CollagenIII_down
ChlorpyrifosCXCL10BSK_hDFCGF_IP10_down
ChlorpyrifosCSF1BSK_hDFCGF_MCSF_down
ChlorpyrifosMMP1BSK_hDFCGF_MMP1_up
ChlorpyrifosSERPINE1BSK_hDFCGF_PAI1_down
ChlorpyrifosVCAM1BSK_hDFCGF_VCAM1_down
ChlorpyrifosCCL2BSK_KF3CT_MCP1_down
ChlorpyrifosCD40BSK_LPS_CD40_down
ChlorpyrifosCSF1BSK_LPS_MCSF_down
ChlorpyrifosVCAM1BSK_LPS_VCAM1_down
ChlorpyrifosCD38BSK_SAg_CD38_down
ChlorpyrifosCD40BSK_SAg_CD40_down
ChlorpyrifosCD69BSK_SAg_CD69_down
ChlorpyrifosSELEBSK_SAg_Eselectin_down
ChlorpyrifosCXCL8BSK_SAg_IL8_down
ChlorpyrifosCCL2BSK_SAg_MCP1_down
ChlorpyrifosNR3C1CEETOX_H295R_11DCORT_dn
ChlorpyrifosNR3C2CEETOX_H295R_11DCORT_dn
ChlorpyrifosARCEETOX_H295R_ANDR_dn
ChlorpyrifosNR3C1CEETOX_H295R_CORTISOL_dn
ChlorpyrifosNR3C2CEETOX_H295R_CORTISOL_dn
ChlorpyrifosPGRCEETOX_H295R_OHPREG_dn
ChlorpyrifosPGRCEETOX_H295R_PROG_up
ChlorpyrifosARCEETOX_H295R_TESTO_dn
ChlorpyrifosSLC5A5NIS_RAIU_inhibition
ChlorpyrifosDUSP3NVS_ENZ_hDUSP3
ChlorpyrifosBCHENVS_ENZ_hES
ChlorpyrifosAROT_AR_ARSRC1_0480
ChlorpyrifosAROT_AR_ARSRC1_0960
ChlorpyrifosESR1OT_ER_ERaERa_0480
ChlorpyrifosESR1OT_ER_ERaERa_1440
ChlorpyrifosESR1OT_ER_ERaERb_0480
ChlorpyrifosESR2OT_ER_ERaERb_0480
ChlorpyrifosESR1OT_ER_ERaERb_1440
ChlorpyrifosESR2OT_ER_ERaERb_1440
ChlorpyrifosESR2OT_ER_ERbERb_0480
ChlorpyrifosNR1H4OT_FXR_FXRSRC1_0480
ChlorpyrifosNR1H4OT_FXR_FXRSRC1_1440
ChlorpyrifosRXRAOT_NURR1_NURR1RXRa_0480
ChlorpyrifosRXRAOT_NURR1_NURR1RXRa_1440
ChlorpyrifosAHRTOX21_AhR_LUC_Agonist
ChlorpyrifosJUNTOX21_AP1_BLA_Agonist_ratio
ChlorpyrifosL1RE1TOX21_AP1_BLA_Agonist_ratio
ChlorpyrifosNFE2L2TOX21_ARE_BLA_agonist_ratio
ChlorpyrifosNR1I3TOX21_CAR_Agonist
ChlorpyrifosPGRTOX21_PR_BLA_Antagonist_ratio
ChlorpyrifosTSHRTOX21_TSHR_Antagonist_ratio

DISCLAIMER

NeurotoxKb is a comprehensive knowledgebase of potential environmental neurotoxicants specific to mammals compiled from well-established resources based on the observed neurotoxic endpoints in published literature. The presence of any of the potential neurotoxicants in publicly available chemical compilations, regulatory lists, and guidelines worldwide is reported here solely to support future research on neurotoxicity of environmental chemicals. We do not claim responsibility for any errors or omission in compiled evidence supporting the neurotoxicity of chemicals in our resource, and hence, users are advised to exercise their own informed decision in using the compiled list of potential neurotoxicants in our resource. Further, this work on the compilation of a resource on potential neurotoxicants and their toxicological endpoints is solely based on our scientific understanding of the topic, and this does not necessarily reflect the views or policies of our employers or funders.