Coumaphos

Coumaphos



Chemical nameGene identifierToxCast assay component endpoint name
CoumaphosARACEA_AR_antagonist_80hr
CoumaphosCREB3ATG_CRE_CIS_up
CoumaphosRARAATG_DR5_CIS_up
CoumaphosRARBATG_DR5_CIS_up
CoumaphosRARGATG_DR5_CIS_up
CoumaphosESR1ATG_ERE_CIS_up
CoumaphosNFE2L2ATG_NRF2_ARE_CIS_up
CoumaphosPPARAATG_PPRE_CIS_up
CoumaphosPPARDATG_PPRE_CIS_up
CoumaphosPPARGATG_PPRE_CIS_up
CoumaphosNR1I2ATG_PXRE_CIS_up
CoumaphosNR1I2ATG_PXR_TRANS_up
CoumaphosRARAATG_RARa_TRANS_up
CoumaphosVDRATG_VDRE_CIS_up
CoumaphosHLA-DRABSK_3C_HLADR_down
CoumaphosTHBDBSK_3C_Thrombomodulin_up
CoumaphosTHBDBSK_CASM3C_Thrombomodulin_up
CoumaphosCOL3A1BSK_hDFCGF_CollagenIII_down
CoumaphosCXCL10BSK_hDFCGF_IP10_down
CoumaphosCSF1BSK_hDFCGF_MCSF_down
CoumaphosMMP1BSK_hDFCGF_MMP1_up
CoumaphosVCAM1BSK_hDFCGF_VCAM1_down
CoumaphosIL1ABSK_KF3CT_IL1a_down
CoumaphosMMP9BSK_KF3CT_MMP9_down
CoumaphosCD40BSK_LPS_CD40_down
CoumaphosF3BSK_LPS_TissueFactor_down
CoumaphosSELEBSK_SAg_Eselectin_down
CoumaphosCXCL8BSK_SAg_IL8_down
CoumaphosNR3C1CEETOX_H295R_11DCORT_dn
CoumaphosNR3C2CEETOX_H295R_11DCORT_dn
CoumaphosNR3C1CEETOX_H295R_DOC_dn
CoumaphosNR3C2CEETOX_H295R_DOC_dn
CoumaphosESR1CEETOX_H295R_ESTRADIOL_up
CoumaphosESR2CEETOX_H295R_ESTRADIOL_up
CoumaphosESR1CEETOX_H295R_ESTRONE_up
CoumaphosESR2CEETOX_H295R_ESTRONE_up
CoumaphosPGRCEETOX_H295R_OHPROG_up
CoumaphosPGRCEETOX_H295R_PROG_up
CoumaphosCYP1A1CLD_CYP1A1_24hr
CoumaphosCYP1A1CLD_CYP1A1_48hr
CoumaphosCYP1A2CLD_CYP1A2_24hr
CoumaphosCYP1A2CLD_CYP1A2_48hr
CoumaphosCYP2B6CLD_CYP2B6_24hr
CoumaphosCYP2B6CLD_CYP2B6_48hr
CoumaphosCYP2B6CLD_CYP2B6_6hr
CoumaphosCYP3A4CLD_CYP3A4_24hr
CoumaphosCYP3A4CLD_CYP3A4_48hr
CoumaphosHMGCS2CLD_HMGCS2_48hr
CoumaphosHMGCS2CLD_HMGCS2_6hr
CoumaphosSULT2A1CLD_SULT2A_48hr
CoumaphosUGT1A1CLD_UGT1A1_24hr
CoumaphosSLC5A5NIS_RAIU_inhibition
CoumaphosCYP1A1NVS_ADME_hCYP1A1
CoumaphosCYP1A2NVS_ADME_hCYP1A2
CoumaphosCYP2B6NVS_ADME_hCYP2B6
CoumaphosCYP2C18NVS_ADME_hCYP2C18
CoumaphosCYP2C19NVS_ADME_hCYP2C19
CoumaphosCYP2C9NVS_ADME_hCYP2C9
CoumaphosCYP2D6NVS_ADME_hCYP2D6
CoumaphosCYP2J2NVS_ADME_hCYP2J2
CoumaphosTSPONVS_MP_hPBR
CoumaphosPGRNVS_NR_hPR
CoumaphosAROT_AR_ARSRC1_0960
CoumaphosNR1H4OT_FXR_FXRSRC1_0480
CoumaphosNR1H4OT_FXR_FXRSRC1_1440
CoumaphosAHRTOX21_AhR_LUC_Agonist
CoumaphosARTOX21_AR_BLA_Antagonist_ratio
CoumaphosARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
CoumaphosARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
CoumaphosNR1I3TOX21_CAR_Agonist
CoumaphosESR2TOX21_ERb_BLA_Antagonist_ratio
CoumaphosESRRATOX21_ERR_Antagonist
CoumaphosNR1H4TOX21_FXR_BLA_antagonist_ratio
CoumaphosPGRTOX21_PR_BLA_Antagonist_ratio
CoumaphosTSHRTOX21_TSHR_Antagonist_ratio
CoumaphosTSHRTOX21_TSHR_wt_ratio

DISCLAIMER

NeurotoxKb is a comprehensive knowledgebase of potential environmental neurotoxicants specific to mammals compiled from well-established resources based on the observed neurotoxic endpoints in published literature. The presence of any of the potential neurotoxicants in publicly available chemical compilations, regulatory lists, and guidelines worldwide is reported here solely to support future research on neurotoxicity of environmental chemicals. We do not claim responsibility for any errors or omission in compiled evidence supporting the neurotoxicity of chemicals in our resource, and hence, users are advised to exercise their own informed decision in using the compiled list of potential neurotoxicants in our resource. Further, this work on the compilation of a resource on potential neurotoxicants and their toxicological endpoints is solely based on our scientific understanding of the topic, and this does not necessarily reflect the views or policies of our employers or funders.