Endosulfan

Endosulfan



Chemical nameGene identifierToxCast assay component endpoint name
EndosulfanARACEA_AR_antagonist_80hr
EndosulfanRARAATG_DR5_CIS_up
EndosulfanRARBATG_DR5_CIS_up
EndosulfanRARGATG_DR5_CIS_up
EndosulfanESR1ATG_ERa_TRANS_up
EndosulfanESR1ATG_ERE_CIS_up
EndosulfanNR1I3ATG_PBREM_CIS_up
EndosulfanNR1I2ATG_PXRE_CIS_up
EndosulfanSELEBSK_3C_Eselectin_down
EndosulfanHLA-DRABSK_3C_HLADR_down
EndosulfanICAM1BSK_3C_ICAM1_down
EndosulfanCXCL8BSK_3C_IL8_down
EndosulfanCCL2BSK_3C_MCP1_down
EndosulfanCXCL9BSK_3C_MIG_down
EndosulfanF3BSK_3C_TissueFactor_down
EndosulfanPLAURBSK_3C_uPAR_down
EndosulfanVCAM1BSK_3C_VCAM1_down
EndosulfanCCL26BSK_4H_Eotaxin3_down
EndosulfanCCL2BSK_4H_MCP1_down
EndosulfanSELPBSK_4H_Pselectin_down
EndosulfanPLAURBSK_4H_uPAR_down
EndosulfanVCAM1BSK_4H_VCAM1_down
EndosulfanKDRBSK_4H_VEGFRII_down
EndosulfanHLA-DRABSK_BE3C_HLADR_down
EndosulfanIL1ABSK_BE3C_IL1a_down
EndosulfanCXCL10BSK_BE3C_IP10_down
EndosulfanCXCL9BSK_BE3C_MIG_down
EndosulfanMMP1BSK_BE3C_MMP1_down
EndosulfanSERPINE1BSK_BE3C_PAI1_down
EndosulfanTGFB1BSK_BE3C_TGFb1_down
EndosulfanPLATBSK_BE3C_tPA_down
EndosulfanPLAUBSK_BE3C_uPA_down
EndosulfanPLAURBSK_BE3C_uPAR_down
EndosulfanHLA-DRABSK_CASM3C_HLADR_down
EndosulfanCXCL8BSK_CASM3C_IL8_down
EndosulfanCCL2BSK_CASM3C_MCP1_down
EndosulfanCSF1BSK_CASM3C_MCSF_down
EndosulfanCXCL9BSK_CASM3C_MIG_down
EndosulfanSAA1BSK_CASM3C_SAA_down
EndosulfanTHBDBSK_CASM3C_Thrombomodulin_up
EndosulfanPLAURBSK_CASM3C_uPAR_down
EndosulfanVCAM1BSK_CASM3C_VCAM1_down
EndosulfanCOL3A1BSK_hDFCGF_CollagenIII_down
EndosulfanCXCL8BSK_hDFCGF_IL8_down
EndosulfanCXCL10BSK_hDFCGF_IP10_down
EndosulfanCSF1BSK_hDFCGF_MCSF_down
EndosulfanCXCL9BSK_hDFCGF_MIG_down
EndosulfanMMP1BSK_hDFCGF_MMP1_down
EndosulfanSERPINE1BSK_hDFCGF_PAI1_down
EndosulfanTIMP1BSK_hDFCGF_TIMP1_down
EndosulfanVCAM1BSK_hDFCGF_VCAM1_down
EndosulfanICAM1BSK_KF3CT_ICAM1_down
EndosulfanIL1ABSK_KF3CT_IL1a_down
EndosulfanCXCL10BSK_KF3CT_IP10_down
EndosulfanCCL2BSK_KF3CT_MCP1_down
EndosulfanMMP9BSK_KF3CT_MMP9_down
EndosulfanTIMP2BSK_KF3CT_TIMP2_down
EndosulfanPLAUBSK_KF3CT_uPA_down
EndosulfanCD40BSK_LPS_CD40_down
EndosulfanSELEBSK_LPS_Eselectin_down
EndosulfanIL1ABSK_LPS_IL1a_down
EndosulfanCXCL8BSK_LPS_IL8_down
EndosulfanCCL2BSK_LPS_MCP1_down
EndosulfanCSF1BSK_LPS_MCSF_down
EndosulfanF3BSK_LPS_TissueFactor_down
EndosulfanTNFBSK_LPS_TNFa_down
EndosulfanVCAM1BSK_LPS_VCAM1_down
EndosulfanCD38BSK_SAg_CD38_down
EndosulfanCD40BSK_SAg_CD40_down
EndosulfanCD69BSK_SAg_CD69_down
EndosulfanSELEBSK_SAg_Eselectin_down
EndosulfanCXCL8BSK_SAg_IL8_down
EndosulfanCCL2BSK_SAg_MCP1_down
EndosulfanCXCL9BSK_SAg_MIG_down
EndosulfanABCB1CLD_ABCB1_48hr
EndosulfanCYP2B6CLD_CYP2B6_24hr
EndosulfanCYP2B6CLD_CYP2B6_48hr
EndosulfanCYP2B6CLD_CYP2B6_6hr
EndosulfanCYP3A4CLD_CYP3A4_24hr
EndosulfanCYP3A4CLD_CYP3A4_48hr
EndosulfanCYP3A4CLD_CYP3A4_6hr
EndosulfanUGT1A1CLD_UGT1A1_24hr
EndosulfanSLC5A5NIS_RAIU_inhibition
EndosulfanCYP2B6NVS_ADME_hCYP2B6
EndosulfanCYP2C19NVS_ADME_hCYP2C19
EndosulfanNR1I3NVS_NR_hCAR_Antagonist
EndosulfanNR3C1NVS_NR_hGR
EndosulfanSLC6A3NVS_TR_hDAT
EndosulfanAROT_AR_ARSRC1_0480
EndosulfanAROT_AR_ARSRC1_0960
EndosulfanESR2OT_ER_ERbERb_0480
EndosulfanNR1H4OT_FXR_FXRSRC1_0480
EndosulfanJUNTOX21_AP1_BLA_Agonist_ratio
EndosulfanL1RE1TOX21_AP1_BLA_Agonist_ratio
EndosulfanARTOX21_AR_BLA_Agonist_ratio
EndosulfanARTOX21_AR_BLA_Antagonist_ratio
EndosulfanNFE2L2TOX21_ARE_BLA_agonist_ratio
EndosulfanARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
EndosulfanARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
EndosulfanCYP19A1TOX21_Aromatase_Inhibition
EndosulfanNR1I3TOX21_CAR_Agonist
EndosulfanESR1TOX21_ERa_BLA_Agonist_ratio
EndosulfanESR1TOX21_ERa_BLA_Antagonist_ratio
EndosulfanESR1TOX21_ERa_LUC_VM7_Agonist
EndosulfanESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
EndosulfanESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
EndosulfanESR2TOX21_ERb_BLA_Antagonist_ratio
EndosulfanESRRATOX21_ERR_Antagonist
EndosulfanATF6TOX21_ESRE_BLA_ratio
EndosulfanNR1H4TOX21_FXR_BLA_agonist_ratio
EndosulfanNR1H4TOX21_FXR_BLA_antagonist_ratio
EndosulfanNR3C1TOX21_GR_BLA_Agonist_ratio
EndosulfanHIF1ATOX21_HRE_BLA_Agonist_ratio
EndosulfanHSF1TOX21_HSE_BLA_agonist_ratio
EndosulfanNFKB1TOX21_NFkB_BLA_agonist_ratio
EndosulfanTP53TOX21_p53_BLA_p1_ratio
EndosulfanTP53TOX21_p53_BLA_p2_ratio
EndosulfanTP53TOX21_p53_BLA_p4_ratio
EndosulfanTP53TOX21_p53_BLA_p5_ratio
EndosulfanESRRATOX21_PGC_ERR_Antagonist
EndosulfanPPARDTOX21_PPARd_BLA_agonist_ratio
EndosulfanPGRTOX21_PR_BLA_Antagonist_ratio
EndosulfanTSHRTOX21_TSHR_Agonist_ratio
EndosulfanCYP24A1TOX21_VDR_BLA_agonist_ratio
EndosulfanVDRTOX21_VDR_BLA_agonist_ratio
EndosulfanCYP24A1TOX21_VDR_BLA_antagonist_ratio
EndosulfanVDRTOX21_VDR_BLA_antagonist_ratio

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