Haloperidol

Haloperidol



Chemical nameGene identifierToxCast assay component endpoint name
HaloperidolARACEA_AR_antagonist_80hr
HaloperidolTP53APR_HepG2_p53Act_24h_up
HaloperidolTP53APR_HepG2_p53Act_72h_up
HaloperidolFOSATG_AP_1_CIS_up
HaloperidolJUNATG_AP_1_CIS_up
HaloperidolTFAP2AATG_AP_2_CIS_dn
HaloperidolTFAP2BATG_AP_2_CIS_dn
HaloperidolTFAP2DATG_AP_2_CIS_dn
HaloperidolCREB3ATG_CRE_CIS_up
HaloperidolNR1H2ATG_DR4_LXR_CIS_dn
HaloperidolNR1H3ATG_DR4_LXR_CIS_dn
HaloperidolRARAATG_DR5_CIS_up
HaloperidolRARBATG_DR5_CIS_up
HaloperidolRARGATG_DR5_CIS_up
HaloperidolUSF1ATG_E_Box_CIS_dn
HaloperidolEGR1ATG_EGR_CIS_up
HaloperidolESR1ATG_ERE_CIS_up
HaloperidolFOXA2ATG_FoxA2_CIS_up
HaloperidolFOXO1ATG_FoxO_CIS_up
HaloperidolFOXO3ATG_FoxO_CIS_up
HaloperidolGATA1ATG_GATA_CIS_up
HaloperidolNR3C1ATG_GRE_CIS_up
HaloperidolHIF1AATG_HIF1a_CIS_up
HaloperidolONECUT1ATG_HNF6_CIS_up
HaloperidolHSF1ATG_HSE_CIS_up
HaloperidolNR1H4ATG_IR1_CIS_dn
HaloperidolMTF1ATG_MRE_CIS_up
HaloperidolNFE2L2ATG_NRF2_ARE_CIS_up
HaloperidolPOU2F1ATG_Oct_MLP_CIS_up
HaloperidolTP53ATG_p53_CIS_dn
HaloperidolPAX6ATG_Pax6_CIS_up
HaloperidolNR1I3ATG_PBREM_CIS_up
HaloperidolPPARAATG_PPRE_CIS_up
HaloperidolPPARDATG_PPRE_CIS_up
HaloperidolPPARGATG_PPRE_CIS_up
HaloperidolNR1I2ATG_PXRE_CIS_up
HaloperidolNR1I2ATG_PXR_TRANS_up
HaloperidolRORAATG_RORE_CIS_up
HaloperidolRORBATG_RORE_CIS_up
HaloperidolRORCATG_RORE_CIS_up
HaloperidolSOX1ATG_Sox_CIS_up
HaloperidolSP1ATG_Sp1_CIS_up
HaloperidolSREBF1ATG_SREBP_CIS_up
HaloperidolSTAT3ATG_STAT3_CIS_up
HaloperidolLEF1ATG_TCF_b_cat_CIS_dn
HaloperidolTCF7ATG_TCF_b_cat_CIS_dn
HaloperidolTCF7L1ATG_TCF_b_cat_CIS_dn
HaloperidolTCF7L2ATG_TCF_b_cat_CIS_dn
HaloperidolVDRATG_VDRE_CIS_up
HaloperidolXBP1ATG_Xbp1_CIS_up
HaloperidolHLA-DRABSK_3C_HLADR_down
HaloperidolCXCL8BSK_3C_IL8_down
HaloperidolPLAURBSK_3C_uPAR_down
HaloperidolPLAURBSK_4H_uPAR_down
HaloperidolVCAM1BSK_4H_VCAM1_down
HaloperidolLDLRBSK_CASM3C_LDLR_up
HaloperidolCOL3A1BSK_hDFCGF_CollagenIII_down
HaloperidolSELEBSK_LPS_Eselectin_up
HaloperidolCCL2BSK_LPS_MCP1_down
HaloperidolF3BSK_LPS_TissueFactor_up
HaloperidolSELEBSK_SAg_Eselectin_down
HaloperidolNR3C1CEETOX_H295R_11DCORT_dn
HaloperidolNR3C2CEETOX_H295R_11DCORT_dn
HaloperidolARCEETOX_H295R_ANDR_dn
HaloperidolNR3C1CEETOX_H295R_DOC_dn
HaloperidolNR3C2CEETOX_H295R_DOC_dn
HaloperidolPGRCEETOX_H295R_OHPREG_dn
HaloperidolPGRCEETOX_H295R_OHPROG_dn
HaloperidolPGRCEETOX_H295R_PROG_dn
HaloperidolARCEETOX_H295R_TESTO_dn
HaloperidolCYP2D6NVS_ADME_hCYP2D6
HaloperidolBCHENVS_ENZ_hES
HaloperidolHTR6NVS_GPCR_h5HT6
HaloperidolHTR7NVS_GPCR_h5HT7
HaloperidolADRA2ANVS_GPCR_hAdra2A
HaloperidolADRA2CNVS_GPCR_hAdra2C
HaloperidolADRB1NVS_GPCR_hAdrb1
HaloperidolADRB2NVS_GPCR_hAdrb2
HaloperidolADRB3NVS_GPCR_hAdrb3
HaloperidolDRD1NVS_GPCR_hDRD1
HaloperidolDRD2NVS_GPCR_hDRD2s
HaloperidolDRD4NVS_GPCR_hDRD4.4
HaloperidolHRH1NVS_GPCR_hH1
HaloperidolCHRM1NVS_GPCR_hM1
HaloperidolCHRM2NVS_GPCR_hM2
HaloperidolCHRM4NVS_GPCR_hM4
HaloperidolCHRM5NVS_GPCR_hM5
HaloperidolTACR2NVS_GPCR_hNK2
HaloperidolOPRM1NVS_GPCR_hOpiate_mu
HaloperidolSLC6A3NVS_TR_hDAT
HaloperidolSLC6A2NVS_TR_hNET
HaloperidolSLC6A4NVS_TR_hSERT
HaloperidolAROT_AR_ARSRC1_0480
HaloperidolESR1OT_ER_ERaERb_1440
HaloperidolESR2OT_ER_ERaERb_1440
HaloperidolRXRAOT_NURR1_NURR1RXRa_0480
HaloperidolRXRAOT_NURR1_NURR1RXRa_1440
HaloperidolARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
HaloperidolNR1I3TOX21_CAR_Antagonist
HaloperidolESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
HaloperidolPGRTOX21_PR_BLA_Antagonist_ratio

DISCLAIMER

NeurotoxKb is a comprehensive knowledgebase of potential environmental neurotoxicants specific to mammals compiled from well-established resources based on the observed neurotoxic endpoints in published literature. The presence of any of the potential neurotoxicants in publicly available chemical compilations, regulatory lists, and guidelines worldwide is reported here solely to support future research on neurotoxicity of environmental chemicals. We do not claim responsibility for any errors or omission in compiled evidence supporting the neurotoxicity of chemicals in our resource, and hence, users are advised to exercise their own informed decision in using the compiled list of potential neurotoxicants in our resource. Further, this work on the compilation of a resource on potential neurotoxicants and their toxicological endpoints is solely based on our scientific understanding of the topic, and this does not necessarily reflect the views or policies of our employers or funders.