Naled

Naled



Chemical nameGene identifierToxCast assay component endpoint name
NaledARACEA_AR_antagonist_80hr
NaledTP53APR_HepG2_p53Act_24h_up
NaledTP53APR_HepG2_p53Act_72h_dn
NaledSELEBSK_3C_Eselectin_down
NaledHLA-DRABSK_3C_HLADR_down
NaledICAM1BSK_3C_ICAM1_down
NaledCXCL8BSK_3C_IL8_down
NaledCCL2BSK_3C_MCP1_down
NaledCXCL9BSK_3C_MIG_down
NaledF3BSK_3C_TissueFactor_down
NaledPLAURBSK_3C_uPAR_down
NaledVCAM1BSK_3C_VCAM1_down
NaledCCL26BSK_4H_Eotaxin3_down
NaledCCL2BSK_4H_MCP1_down
NaledSELPBSK_4H_Pselectin_down
NaledPLAURBSK_4H_uPAR_down
NaledVCAM1BSK_4H_VCAM1_down
NaledKDRBSK_4H_VEGFRII_down
NaledHLA-DRABSK_BE3C_HLADR_down
NaledIL1ABSK_BE3C_IL1a_down
NaledCXCL10BSK_BE3C_IP10_down
NaledCXCL9BSK_BE3C_MIG_down
NaledSERPINE1BSK_BE3C_PAI1_down
NaledTGFB1BSK_BE3C_TGFb1_down
NaledPLAUBSK_BE3C_uPA_down
NaledHLA-DRABSK_CASM3C_HLADR_down
NaledIL6BSK_CASM3C_IL6_down
NaledCXCL8BSK_CASM3C_IL8_down
NaledCCL2BSK_CASM3C_MCP1_down
NaledCSF1BSK_CASM3C_MCSF_down
NaledCXCL9BSK_CASM3C_MIG_down
NaledSAA1BSK_CASM3C_SAA_down
NaledTHBDBSK_CASM3C_Thrombomodulin_up
NaledPLAURBSK_CASM3C_uPAR_down
NaledVCAM1BSK_CASM3C_VCAM1_down
NaledCOL3A1BSK_hDFCGF_CollagenIII_down
NaledCXCL8BSK_hDFCGF_IL8_down
NaledCXCL10BSK_hDFCGF_IP10_down
NaledCSF1BSK_hDFCGF_MCSF_down
NaledCXCL9BSK_hDFCGF_MIG_down
NaledMMP1BSK_hDFCGF_MMP1_down
NaledSERPINE1BSK_hDFCGF_PAI1_down
NaledTIMP1BSK_hDFCGF_TIMP1_down
NaledVCAM1BSK_hDFCGF_VCAM1_down
NaledICAM1BSK_KF3CT_ICAM1_down
NaledIL1ABSK_KF3CT_IL1a_down
NaledCXCL10BSK_KF3CT_IP10_down
NaledCCL2BSK_KF3CT_MCP1_down
NaledMMP9BSK_KF3CT_MMP9_down
NaledTGFB1BSK_KF3CT_TGFb1_down
NaledTIMP2BSK_KF3CT_TIMP2_down
NaledPLAUBSK_KF3CT_uPA_down
NaledCD40BSK_LPS_CD40_down
NaledSELEBSK_LPS_Eselectin_down
NaledIL1ABSK_LPS_IL1a_down
NaledCXCL8BSK_LPS_IL8_down
NaledCCL2BSK_LPS_MCP1_down
NaledCSF1BSK_LPS_MCSF_down
NaledF3BSK_LPS_TissueFactor_down
NaledTNFBSK_LPS_TNFa_down
NaledVCAM1BSK_LPS_VCAM1_down
NaledCD38BSK_SAg_CD38_down
NaledCD40BSK_SAg_CD40_down
NaledCD69BSK_SAg_CD69_down
NaledSELEBSK_SAg_Eselectin_down
NaledCXCL8BSK_SAg_IL8_down
NaledCCL2BSK_SAg_MCP1_down
NaledCXCL9BSK_SAg_MIG_down
NaledCYP2C19NVS_ADME_hCYP2C19
NaledACHENVS_ENZ_hAChE
NaledBCHENVS_ENZ_hES
NaledSIRT1NVS_ENZ_hSIRT1
NaledHTR6NVS_GPCR_h5HT6
NaledAGTR1NVS_GPCR_hAT1
NaledDRD1NVS_GPCR_hDRD1
NaledNPY1RNVS_GPCR_hNPY1
NaledOPRM1NVS_GPCR_hOpiate_mu
NaledAROT_AR_ARSRC1_0960
NaledJUNTOX21_AP1_BLA_Agonist_ratio
NaledL1RE1TOX21_AP1_BLA_Agonist_ratio
NaledARTOX21_AR_BLA_Agonist_ratio
NaledARTOX21_AR_BLA_Antagonist_ratio
NaledNFE2L2TOX21_ARE_BLA_agonist_ratio
NaledARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
NaledARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
NaledCYP19A1TOX21_Aromatase_Inhibition
NaledATAD5TOX21_ELG1_LUC_Agonist
NaledESR1TOX21_ERa_BLA_Agonist_ratio
NaledESR1TOX21_ERa_LUC_VM7_Agonist
NaledNR1H4TOX21_FXR_BLA_agonist_ratio
NaledTP53TOX21_p53_BLA_p1_ratio
NaledTP53TOX21_p53_BLA_p2_ratio
NaledTP53TOX21_p53_BLA_p3_ratio
NaledTP53TOX21_p53_BLA_p4_ratio
NaledTP53TOX21_p53_BLA_p5_ratio
NaledPPARGTOX21_PPARg_BLA_Agonist_ratio
NaledPPARGTOX21_PPARg_BLA_antagonist_ratio
NaledTSHRTOX21_TSHR_Agonist_ratio
NaledCYP24A1TOX21_VDR_BLA_antagonist_ratio
NaledVDRTOX21_VDR_BLA_antagonist_ratio

DISCLAIMER

NeurotoxKb is a comprehensive knowledgebase of potential environmental neurotoxicants specific to mammals compiled from well-established resources based on the observed neurotoxic endpoints in published literature. The presence of any of the potential neurotoxicants in publicly available chemical compilations, regulatory lists, and guidelines worldwide is reported here solely to support future research on neurotoxicity of environmental chemicals. We do not claim responsibility for any errors or omission in compiled evidence supporting the neurotoxicity of chemicals in our resource, and hence, users are advised to exercise their own informed decision in using the compiled list of potential neurotoxicants in our resource. Further, this work on the compilation of a resource on potential neurotoxicants and their toxicological endpoints is solely based on our scientific understanding of the topic, and this does not necessarily reflect the views or policies of our employers or funders.