Toxaphene

Toxaphene



Chemical nameGene identifierToxCast assay component endpoint name
ToxapheneJUNTOX21_AP1_BLA_Agonist_ratio
ToxapheneL1RE1TOX21_AP1_BLA_Agonist_ratio
ToxapheneARTOX21_AR_BLA_Agonist_ratio
ToxapheneARTOX21_AR_BLA_Antagonist_ratio
ToxapheneNFE2L2TOX21_ARE_BLA_agonist_ratio
ToxapheneARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
ToxapheneARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
ToxapheneCYP19A1TOX21_Aromatase_Inhibition
ToxapheneNR1I3TOX21_CAR_Agonist
ToxapheneESR1TOX21_ERa_BLA_Agonist_ratio
ToxapheneESR1TOX21_ERa_BLA_Antagonist_ratio
ToxapheneESR1TOX21_ERa_LUC_VM7_Agonist
ToxapheneESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
ToxapheneESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
ToxapheneESR2TOX21_ERb_BLA_Antagonist_ratio
ToxapheneESRRATOX21_ERR_Antagonist
ToxapheneATF6TOX21_ESRE_BLA_ratio
ToxapheneNR1H4TOX21_FXR_BLA_agonist_ratio
ToxapheneNR1H4TOX21_FXR_BLA_antagonist_ratio
ToxapheneNR3C1TOX21_GR_BLA_Agonist_ratio
ToxapheneNR3C1TOX21_GR_BLA_Antagonist_ratio
ToxapheneHIF1ATOX21_HRE_BLA_Agonist_ratio
ToxapheneHSF1TOX21_HSE_BLA_agonist_ratio
ToxapheneNFKB1TOX21_NFkB_BLA_agonist_ratio
ToxapheneTP53TOX21_p53_BLA_p1_ratio
ToxapheneTP53TOX21_p53_BLA_p2_ratio
ToxapheneTP53TOX21_p53_BLA_p3_ratio
ToxapheneTP53TOX21_p53_BLA_p4_ratio
ToxapheneTP53TOX21_p53_BLA_p5_ratio
ToxapheneESRRATOX21_PGC_ERR_Antagonist
ToxaphenePPARDTOX21_PPARd_BLA_agonist_ratio
ToxaphenePPARGTOX21_PPARg_BLA_Agonist_ratio
ToxaphenePPARGTOX21_PPARg_BLA_antagonist_ratio
ToxaphenePGRTOX21_PR_BLA_Antagonist_ratio
ToxapheneTSHRTOX21_TSHR_Agonist_ratio
ToxapheneCYP24A1TOX21_VDR_BLA_agonist_ratio
ToxapheneVDRTOX21_VDR_BLA_agonist_ratio
ToxapheneCYP24A1TOX21_VDR_BLA_antagonist_ratio
ToxapheneVDRTOX21_VDR_BLA_antagonist_ratio

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NeurotoxKb is a comprehensive knowledgebase of potential environmental neurotoxicants specific to mammals compiled from well-established resources based on the observed neurotoxic endpoints in published literature. The presence of any of the potential neurotoxicants in publicly available chemical compilations, regulatory lists, and guidelines worldwide is reported here solely to support future research on neurotoxicity of environmental chemicals. We do not claim responsibility for any errors or omission in compiled evidence supporting the neurotoxicity of chemicals in our resource, and hence, users are advised to exercise their own informed decision in using the compiled list of potential neurotoxicants in our resource. Further, this work on the compilation of a resource on potential neurotoxicants and their toxicological endpoints is solely based on our scientific understanding of the topic, and this does not necessarily reflect the views or policies of our employers or funders.