Trichlorfon

Trichlorfon



Chemical nameGene identifierToxCast assay component endpoint name
TrichlorfonARACEA_AR_antagonist_80hr
TrichlorfonTP53APR_HepG2_p53Act_72h_dn
TrichlorfonFOSATG_AP_1_CIS_up
TrichlorfonJUNATG_AP_1_CIS_up
TrichlorfonSMAD1ATG_BRE_CIS_up
TrichlorfonCEBPBATG_C_EBP_CIS_up
TrichlorfonCREB3ATG_CRE_CIS_up
TrichlorfonEGR1ATG_EGR_CIS_up
TrichlorfonESR1ATG_ERa_TRANS_up
TrichlorfonETS1ATG_Ets_CIS_dn
TrichlorfonNR1H4ATG_FXR_TRANS_up
TrichlorfonNR3C1ATG_GRE_CIS_dn
TrichlorfonHNF4AATG_HNF4a_TRANS_up
TrichlorfonNR1H3ATG_LXRa_TRANS_up
TrichlorfonNR1H2ATG_LXRb_TRANS_up
TrichlorfonMTF1ATG_MRE_CIS_up
TrichlorfonMYCATG_Myc_CIS_up
TrichlorfonNFE2L2ATG_NRF2_ARE_CIS_up
TrichlorfonPOU2F1ATG_Oct_MLP_CIS_up
TrichlorfonTP53ATG_p53_CIS_up
TrichlorfonPPARGATG_PPARg_TRANS_up
TrichlorfonPPARAATG_PPRE_CIS_up
TrichlorfonPPARDATG_PPRE_CIS_up
TrichlorfonPPARGATG_PPRE_CIS_up
TrichlorfonNR1I2ATG_PXRE_CIS_up
TrichlorfonRARAATG_RARa_TRANS_up
TrichlorfonRORAATG_RORE_CIS_up
TrichlorfonRORBATG_RORE_CIS_up
TrichlorfonRORCATG_RORE_CIS_up
TrichlorfonSP1ATG_Sp1_CIS_up
TrichlorfonSREBF1ATG_SREBP_CIS_up
TrichlorfonTHRAATG_THRa1_TRANS_up
TrichlorfonVDRATG_VDRE_CIS_up
TrichlorfonVDRATG_VDR_TRANS_up
TrichlorfonXBP1ATG_Xbp1_CIS_up
TrichlorfonHLA-DRABSK_BE3C_HLADR_up
TrichlorfonPLAURBSK_BE3C_uPAR_up
TrichlorfonPTGER2BSK_LPS_PGE2_up
TrichlorfonSELEBSK_SAg_Eselectin_down
TrichlorfonUGT1A1CLD_UGT1A1_48hr
TrichlorfonESR1OT_ERa_EREGFP_0480
TrichlorfonESR1OT_ER_ERaERb_0480
TrichlorfonESR2OT_ER_ERaERb_0480
TrichlorfonESR1OT_ER_ERaERb_1440
TrichlorfonESR2OT_ER_ERaERb_1440
TrichlorfonESR2OT_ER_ERbERb_0480
TrichlorfonESR2OT_ER_ERbERb_1440
TrichlorfonNR1H4OT_FXR_FXRSRC1_1440
TrichlorfonARTOX21_AR_BLA_Agonist_ratio
TrichlorfonNFE2L2TOX21_ARE_BLA_agonist_ratio
TrichlorfonESR1TOX21_ERa_LUC_VM7_Agonist
TrichlorfonESRRATOX21_ERR_Antagonist
TrichlorfonPGRTOX21_PR_BLA_Antagonist_ratio

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NeurotoxKb is a comprehensive knowledgebase of potential environmental neurotoxicants specific to mammals compiled from well-established resources based on the observed neurotoxic endpoints in published literature. The presence of any of the potential neurotoxicants in publicly available chemical compilations, regulatory lists, and guidelines worldwide is reported here solely to support future research on neurotoxicity of environmental chemicals. We do not claim responsibility for any errors or omission in compiled evidence supporting the neurotoxicity of chemicals in our resource, and hence, users are advised to exercise their own informed decision in using the compiled list of potential neurotoxicants in our resource. Further, this work on the compilation of a resource on potential neurotoxicants and their toxicological endpoints is solely based on our scientific understanding of the topic, and this does not necessarily reflect the views or policies of our employers or funders.