Chlordane

Chlordane



Chemical nameGene identifierToxCast assay component endpoint name
ChlordaneARACEA_AR_antagonist_80hr
ChlordaneESR1ACEA_ER_80hr
ChlordaneTP53APR_HepG2_p53Act_24h_up
ChlordaneTP53APR_HepG2_p53Act_72h_up
ChlordaneFOSATG_AP_1_CIS_up
ChlordaneJUNATG_AP_1_CIS_up
ChlordaneNR1H2ATG_DR4_LXR_CIS_dn
ChlordaneNR1H3ATG_DR4_LXR_CIS_dn
ChlordaneRARAATG_DR5_CIS_up
ChlordaneRARBATG_DR5_CIS_up
ChlordaneRARGATG_DR5_CIS_up
ChlordaneUSF1ATG_E_Box_CIS_dn
ChlordaneEGR1ATG_EGR_CIS_up
ChlordaneESR1ATG_ERa_TRANS_up
ChlordaneESR1ATG_ERE_CIS_up
ChlordaneNR1H4ATG_FXR_TRANS_up
ChlordaneNR3C1ATG_GR_TRANS_up
ChlordaneHNF4AATG_HNF4a_TRANS_dn
ChlordaneHSF1ATG_HSE_CIS_up
ChlordaneNR1H4ATG_IR1_CIS_dn
ChlordaneIRF1ATG_ISRE_CIS_dn
ChlordaneMTF1ATG_MRE_CIS_up
ChlordaneNFE2L2ATG_NRF2_ARE_CIS_up
ChlordaneNR4A2ATG_NURR1_TRANS_dn
ChlordanePAX6ATG_Pax6_CIS_up
ChlordanePPARGATG_PPARg_TRANS_up
ChlordanePPARAATG_PPRE_CIS_up
ChlordanePPARDATG_PPRE_CIS_up
ChlordanePPARGATG_PPRE_CIS_up
ChlordaneNR1I2ATG_PXRE_CIS_up
ChlordaneNR1I2ATG_PXR_TRANS_up
ChlordaneRARGATG_RARg_TRANS_up
ChlordaneRORCATG_RORg_TRANS_dn
ChlordaneRXRAATG_RXRa_TRANS_up
ChlordaneRXRBATG_RXRb_TRANS_up
ChlordaneLEF1ATG_TCF_b_cat_CIS_dn
ChlordaneTCF7ATG_TCF_b_cat_CIS_dn
ChlordaneTCF7L1ATG_TCF_b_cat_CIS_dn
ChlordaneTCF7L2ATG_TCF_b_cat_CIS_dn
ChlordaneVDRATG_VDRE_CIS_up
ChlordaneXBP1ATG_Xbp1_CIS_up
ChlordaneSELEBSK_3C_Eselectin_down
ChlordaneHLA-DRABSK_3C_HLADR_down
ChlordaneICAM1BSK_3C_ICAM1_down
ChlordaneCXCL8BSK_3C_IL8_down
ChlordaneCCL2BSK_3C_MCP1_down
ChlordaneCXCL9BSK_3C_MIG_down
ChlordaneF3BSK_3C_TissueFactor_down
ChlordanePLAURBSK_3C_uPAR_down
ChlordaneVCAM1BSK_3C_VCAM1_down
ChlordaneCCL26BSK_4H_Eotaxin3_down
ChlordaneCCL2BSK_4H_MCP1_down
ChlordaneSELPBSK_4H_Pselectin_down
ChlordanePLAURBSK_4H_uPAR_down
ChlordaneVCAM1BSK_4H_VCAM1_down
ChlordaneKDRBSK_4H_VEGFRII_down
ChlordaneHLA-DRABSK_BE3C_HLADR_down
ChlordaneCXCL10BSK_BE3C_IP10_down
ChlordaneCXCL9BSK_BE3C_MIG_down
ChlordaneMMP1BSK_BE3C_MMP1_up
ChlordaneSERPINE1BSK_BE3C_PAI1_down
ChlordaneTGFB1BSK_BE3C_TGFb1_down
ChlordaneHLA-DRABSK_CASM3C_HLADR_down
ChlordaneSAA1BSK_CASM3C_SAA_down
ChlordaneTHBDBSK_CASM3C_Thrombomodulin_up
ChlordaneVCAM1BSK_CASM3C_VCAM1_down
ChlordaneCOL3A1BSK_hDFCGF_CollagenIII_down
ChlordaneCXCL8BSK_hDFCGF_IL8_down
ChlordaneCXCL10BSK_hDFCGF_IP10_down
ChlordaneCSF1BSK_hDFCGF_MCSF_down
ChlordaneCXCL9BSK_hDFCGF_MIG_down
ChlordaneMMP1BSK_hDFCGF_MMP1_down
ChlordaneSERPINE1BSK_hDFCGF_PAI1_down
ChlordaneTIMP1BSK_hDFCGF_TIMP1_down
ChlordaneVCAM1BSK_hDFCGF_VCAM1_down
ChlordaneIL1ABSK_KF3CT_IL1a_down
ChlordaneCXCL10BSK_KF3CT_IP10_down
ChlordaneCCL2BSK_KF3CT_MCP1_down
ChlordaneMMP9BSK_KF3CT_MMP9_down
ChlordaneTGFB1BSK_KF3CT_TGFb1_down
ChlordaneTIMP2BSK_KF3CT_TIMP2_down
ChlordanePLAUBSK_KF3CT_uPA_down
ChlordaneCD40BSK_LPS_CD40_down
ChlordaneSELEBSK_LPS_Eselectin_down
ChlordaneIL1ABSK_LPS_IL1a_down
ChlordaneCXCL8BSK_LPS_IL8_down
ChlordaneCCL2BSK_LPS_MCP1_down
ChlordaneCSF1BSK_LPS_MCSF_down
ChlordaneF3BSK_LPS_TissueFactor_down
ChlordaneTNFBSK_LPS_TNFa_down
ChlordaneVCAM1BSK_LPS_VCAM1_down
ChlordaneCD38BSK_SAg_CD38_down
ChlordaneCD40BSK_SAg_CD40_down
ChlordaneCD69BSK_SAg_CD69_down
ChlordaneSELEBSK_SAg_Eselectin_down
ChlordaneCXCL8BSK_SAg_IL8_down
ChlordaneCCL2BSK_SAg_MCP1_down
ChlordaneCXCL9BSK_SAg_MIG_down
ChlordaneSLC5A5NIS_RAIU_inhibition
ChlordaneCYP2B6NVS_ADME_hCYP2B6
ChlordaneCYP2C19NVS_ADME_hCYP2C19
ChlordanePTPN1NVS_ENZ_hPTPN1_Activator
ChlordanePTPRFNVS_ENZ_hPTPRF_Activator
ChlordaneDRD2NVS_GPCR_hDRD2s
ChlordaneNR3C1NVS_NR_hGR
ChlordaneAROT_AR_ARSRC1_0480
ChlordaneAROT_AR_ARSRC1_0960
ChlordaneESR2OT_ER_ERbERb_0480
ChlordaneESR2OT_ER_ERbERb_1440
ChlordaneJUNTOX21_AP1_BLA_Agonist_ratio
ChlordaneL1RE1TOX21_AP1_BLA_Agonist_ratio
ChlordaneARTOX21_AR_BLA_Agonist_ratio
ChlordaneARTOX21_AR_BLA_Antagonist_ratio
ChlordaneNFE2L2TOX21_ARE_BLA_agonist_ratio
ChlordaneARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
ChlordaneARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
ChlordaneCYP19A1TOX21_Aromatase_Inhibition
ChlordaneNR1I3TOX21_CAR_Agonist
ChlordaneESR1TOX21_ERa_BLA_Antagonist_ratio
ChlordaneESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
ChlordaneESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
ChlordaneESR2TOX21_ERb_BLA_Antagonist_ratio
ChlordaneESRRATOX21_ERR_Antagonist
ChlordaneATF6TOX21_ESRE_BLA_ratio
ChlordaneNR1H4TOX21_FXR_BLA_agonist_ratio
ChlordaneNR1H4TOX21_FXR_BLA_antagonist_ratio
ChlordaneNR3C1TOX21_GR_BLA_Agonist_ratio
ChlordaneHIF1ATOX21_HRE_BLA_Agonist_ratio
ChlordaneHSF1TOX21_HSE_BLA_agonist_ratio
ChlordaneNFKB1TOX21_NFkB_BLA_agonist_ratio
ChlordaneTP53TOX21_p53_BLA_p1_ratio
ChlordaneTP53TOX21_p53_BLA_p2_ratio
ChlordaneTP53TOX21_p53_BLA_p3_ratio
ChlordaneTP53TOX21_p53_BLA_p4_ratio
ChlordaneTP53TOX21_p53_BLA_p5_ratio
ChlordaneESRRATOX21_PGC_ERR_Antagonist
ChlordanePPARDTOX21_PPARd_BLA_agonist_ratio
ChlordanePGRTOX21_PR_BLA_Antagonist_ratio
ChlordaneRXRATOX21_RXR_BLA_Agonist_ratio
ChlordaneTSHRTOX21_TSHR_Agonist_ratio
ChlordaneCYP24A1TOX21_VDR_BLA_agonist_ratio
ChlordaneVDRTOX21_VDR_BLA_agonist_ratio
ChlordaneCYP24A1TOX21_VDR_BLA_antagonist_ratio
ChlordaneVDRTOX21_VDR_BLA_antagonist_ratio

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