Hydroquinone

Hydroquinone



Chemical nameGene identifierToxCast assay component endpoint name
HydroquinoneARACEA_AR_agonist_80hr
HydroquinoneARACEA_AR_antagonist_80hr
HydroquinoneTP53APR_HepG2_p53Act_24h_up
HydroquinoneTP53APR_HepG2_p53Act_72h_up
HydroquinoneAHRATG_Ahr_CIS_up
HydroquinoneFOSATG_AP_1_CIS_up
HydroquinoneJUNATG_AP_1_CIS_up
HydroquinoneTFAP2AATG_AP_2_CIS_up
HydroquinoneTFAP2BATG_AP_2_CIS_up
HydroquinoneTFAP2DATG_AP_2_CIS_up
HydroquinoneSMAD1ATG_BRE_CIS_dn
HydroquinoneRARAATG_DR5_CIS_up
HydroquinoneRARBATG_DR5_CIS_up
HydroquinoneRARGATG_DR5_CIS_up
HydroquinoneESR1ATG_ERa_TRANS_up
HydroquinoneESR1ATG_ERE_CIS_up
HydroquinoneHIF1AATG_HIF1a_CIS_up
HydroquinoneHSF1ATG_HSE_CIS_dn
HydroquinoneMTF1ATG_MRE_CIS_up
HydroquinoneNFKB1ATG_NF_kB_CIS_dn
HydroquinoneNFE2L2ATG_NRF2_ARE_CIS_up
HydroquinoneTP53ATG_p53_CIS_up
HydroquinonePAX6ATG_Pax6_CIS_up
HydroquinonePPARAATG_PPRE_CIS_up
HydroquinonePPARDATG_PPRE_CIS_up
HydroquinonePPARGATG_PPRE_CIS_up
HydroquinoneSTAT3ATG_STAT3_CIS_up
HydroquinoneVDRATG_VDRE_CIS_up
HydroquinoneXBP1ATG_Xbp1_CIS_up
HydroquinoneSELEBSK_3C_Eselectin_down
HydroquinoneHLA-DRABSK_3C_HLADR_down
HydroquinoneVCAM1BSK_3C_VCAM1_down
HydroquinoneCCL26BSK_4H_Eotaxin3_down
HydroquinoneSELPBSK_4H_Pselectin_down
HydroquinoneVCAM1BSK_4H_VCAM1_down
HydroquinoneMMP1BSK_BE3C_MMP1_up
HydroquinonePLAUBSK_BE3C_uPA_up
HydroquinoneHLA-DRABSK_CASM3C_HLADR_down
HydroquinoneCSF1BSK_CASM3C_MCSF_down
HydroquinoneTHBDBSK_CASM3C_Thrombomodulin_up
HydroquinoneVCAM1BSK_CASM3C_VCAM1_down
HydroquinoneCOL3A1BSK_hDFCGF_CollagenIII_down
HydroquinoneCXCL8BSK_hDFCGF_IL8_down
HydroquinoneCXCL10BSK_hDFCGF_IP10_down
HydroquinoneCSF1BSK_hDFCGF_MCSF_down
HydroquinoneCXCL9BSK_hDFCGF_MIG_down
HydroquinoneMMP1BSK_hDFCGF_MMP1_down
HydroquinoneSERPINE1BSK_hDFCGF_PAI1_down
HydroquinoneTIMP1BSK_hDFCGF_TIMP1_down
HydroquinoneVCAM1BSK_hDFCGF_VCAM1_down
HydroquinoneICAM1BSK_KF3CT_ICAM1_down
HydroquinoneCXCL10BSK_KF3CT_IP10_down
HydroquinoneMMP9BSK_KF3CT_MMP9_down
HydroquinoneSELEBSK_LPS_Eselectin_down
HydroquinoneIL1ABSK_LPS_IL1a_down
HydroquinoneCXCL8BSK_LPS_IL8_down
HydroquinoneCCL2BSK_LPS_MCP1_down
HydroquinoneCSF1BSK_LPS_MCSF_down
HydroquinonePTGER2BSK_LPS_PGE2_down
HydroquinoneTNFBSK_LPS_TNFa_down
HydroquinoneVCAM1BSK_LPS_VCAM1_down
HydroquinoneCD38BSK_SAg_CD38_down
HydroquinoneCD40BSK_SAg_CD40_down
HydroquinoneCD69BSK_SAg_CD69_down
HydroquinoneSELEBSK_SAg_Eselectin_down
HydroquinoneNR3C1CEETOX_H295R_DOC_up
HydroquinoneNR3C2CEETOX_H295R_DOC_up
HydroquinonePGRCEETOX_H295R_PROG_up
HydroquinoneNPY1RNVS_GPCR_hNPY1
HydroquinoneOPRM1NVS_GPCR_hOpiate_mu
HydroquinonePPARGNVS_NR_hPPARg
HydroquinoneESR2OT_ER_ERbERb_1440
HydroquinoneNR1H4OT_FXR_FXRSRC1_1440
HydroquinoneRXRAOT_NURR1_NURR1RXRa_1440
HydroquinoneARTOX21_AR_BLA_Antagonist_ratio
HydroquinoneNFE2L2TOX21_ARE_BLA_agonist_ratio
HydroquinoneCYP19A1TOX21_Aromatase_Inhibition
HydroquinoneNR1I3TOX21_CAR_Agonist
HydroquinoneESRRATOX21_ERR_Agonist
HydroquinoneNR3C1TOX21_GR_BLA_Antagonist_ratio
HydroquinoneTP53TOX21_p53_BLA_p2_ratio
HydroquinoneCYP24A1TOX21_VDR_BLA_antagonist_ratio
HydroquinoneVDRTOX21_VDR_BLA_antagonist_ratio

DISCLAIMER

NeurotoxKb is a comprehensive knowledgebase of potential environmental neurotoxicants specific to mammals compiled from well-established resources based on the observed neurotoxic endpoints in published literature. The presence of any of the potential neurotoxicants in publicly available chemical compilations, regulatory lists, and guidelines worldwide is reported here solely to support future research on neurotoxicity of environmental chemicals. We do not claim responsibility for any errors or omission in compiled evidence supporting the neurotoxicity of chemicals in our resource, and hence, users are advised to exercise their own informed decision in using the compiled list of potential neurotoxicants in our resource. Further, this work on the compilation of a resource on potential neurotoxicants and their toxicological endpoints is solely based on our scientific understanding of the topic, and this does not necessarily reflect the views or policies of our employers or funders.