Parathion

Parathion



Chemical nameGene identifierToxCast assay component endpoint name
ParathionARACEA_AR_antagonist_80hr
ParathionAHRATG_Ahr_CIS_up
ParathionFOSATG_AP_1_CIS_up
ParathionJUNATG_AP_1_CIS_up
ParathionSMAD1ATG_BRE_CIS_up
ParathionCEBPBATG_C_EBP_CIS_up
ParathionCREB3ATG_CRE_CIS_up
ParathionEGR1ATG_EGR_CIS_up
ParathionESR1ATG_ERa_TRANS_up
ParathionESR1ATG_ERE_CIS_up
ParathionMTF1ATG_MRE_CIS_up
ParathionNFE2L2ATG_NRF2_ARE_CIS_up
ParathionPOU2F1ATG_Oct_MLP_CIS_up
ParathionPPARGATG_PPARg_TRANS_up
ParathionPPARAATG_PPRE_CIS_up
ParathionPPARDATG_PPRE_CIS_up
ParathionPPARGATG_PPRE_CIS_up
ParathionNR1I2ATG_PXRE_CIS_up
ParathionNR1I2ATG_PXR_TRANS_up
ParathionRORAATG_RORE_CIS_up
ParathionRORBATG_RORE_CIS_up
ParathionRORCATG_RORE_CIS_up
ParathionSREBF1ATG_SREBP_CIS_up
ParathionVDRATG_VDRE_CIS_up
ParathionCCL2BSK_4H_MCP1_down
ParathionTHBDBSK_CASM3C_Thrombomodulin_up
ParathionCXCL10BSK_hDFCGF_IP10_down
ParathionCSF1BSK_hDFCGF_MCSF_down
ParathionMMP1BSK_hDFCGF_MMP1_up
ParathionSERPINE1BSK_hDFCGF_PAI1_down
ParathionVCAM1BSK_hDFCGF_VCAM1_down
ParathionICAM1BSK_KF3CT_ICAM1_up
ParathionCXCL10BSK_KF3CT_IP10_down
ParathionCD40BSK_LPS_CD40_down
ParathionCSF1BSK_LPS_MCSF_down
ParathionPTGER2BSK_LPS_PGE2_up
ParathionVCAM1BSK_LPS_VCAM1_down
ParathionCD38BSK_SAg_CD38_down
ParathionCD69BSK_SAg_CD69_down
ParathionSELEBSK_SAg_Eselectin_down
ParathionNR3C1CEETOX_H295R_11DCORT_dn
ParathionNR3C2CEETOX_H295R_11DCORT_dn
ParathionNR3C1CEETOX_H295R_CORTISOL_dn
ParathionNR3C2CEETOX_H295R_CORTISOL_dn
ParathionNR3C1CEETOX_H295R_DOC_dn
ParathionNR3C2CEETOX_H295R_DOC_dn
ParathionESR1CEETOX_H295R_ESTRONE_up
ParathionESR2CEETOX_H295R_ESTRONE_up
ParathionPGRCEETOX_H295R_OHPROG_up
ParathionPGRCEETOX_H295R_PROG_up
ParathionCYP1A1CLD_CYP1A1_24hr
ParathionCYP1A1CLD_CYP1A1_48hr
ParathionCYP1A1CLD_CYP1A1_6hr
ParathionCYP1A2CLD_CYP1A2_24hr
ParathionCYP1A2CLD_CYP1A2_48hr
ParathionCYP1A2CLD_CYP1A2_6hr
ParathionCYP2B6CLD_CYP2B6_24hr
ParathionCYP2B6CLD_CYP2B6_48hr
ParathionCYP2B6CLD_CYP2B6_6hr
ParathionCYP3A4CLD_CYP3A4_24hr
ParathionCYP3A4CLD_CYP3A4_48hr
ParathionSULT2A1CLD_SULT2A_48hr
ParathionUGT1A1CLD_UGT1A1_24hr
ParathionUGT1A1CLD_UGT1A1_48hr
ParathionSLC5A5NIS_RAIU_inhibition
ParathionCYP1A1NVS_ADME_hCYP1A1
ParathionCYP1A2NVS_ADME_hCYP1A2
ParathionCYP2B6NVS_ADME_hCYP2B6
ParathionCYP2C18NVS_ADME_hCYP2C18
ParathionCYP2C19NVS_ADME_hCYP2C19
ParathionCYP2C9NVS_ADME_hCYP2C9
ParathionCYP2J2NVS_ADME_hCYP2J2
ParathionBCHENVS_ENZ_hES
ParathionCHRM3NVS_GPCR_hM3
ParathionCHRM4NVS_GPCR_hM4
ParathionTSPONVS_MP_hPBR
ParathionARNVS_NR_hAR
ParathionNR3C1NVS_NR_hGR
ParathionPGRNVS_NR_hPR
ParathionSLC6A4NVS_TR_hSERT
ParathionNR1H4OT_FXR_FXRSRC1_0480
ParathionNR1H4OT_FXR_FXRSRC1_1440
ParathionAHRTOX21_AhR_LUC_Agonist
ParathionARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
ParathionNR1I3TOX21_CAR_Agonist
ParathionTP53TOX21_p53_BLA_p2_ratio
ParathionPGRTOX21_PR_BLA_Antagonist_ratio

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NeurotoxKb is a comprehensive knowledgebase of potential environmental neurotoxicants specific to mammals compiled from well-established resources based on the observed neurotoxic endpoints in published literature. The presence of any of the potential neurotoxicants in publicly available chemical compilations, regulatory lists, and guidelines worldwide is reported here solely to support future research on neurotoxicity of environmental chemicals. We do not claim responsibility for any errors or omission in compiled evidence supporting the neurotoxicity of chemicals in our resource, and hence, users are advised to exercise their own informed decision in using the compiled list of potential neurotoxicants in our resource. Further, this work on the compilation of a resource on potential neurotoxicants and their toxicological endpoints is solely based on our scientific understanding of the topic, and this does not necessarily reflect the views or policies of our employers or funders.