8-Quinolinolium 7'-bromo-3'-hydroxy-2'-naphthoate, copper (II) chelate

8-Quinolinolium 7'-bromo-3'-hydroxy-2'-naphthoate, copper (II) chelate



Predicted Toxicity properties
PropertyToolInterpretationProbability/Value
Acute oral toxicityadmetSAR-3.05 kg/mol
Acute oral toxicity classadmetSARIII-
BiodegradationadmetSARNo-
ToxtreeClass 2 (persistent chemical)-
Carcinogenicity (Three class)admetSARNon-required-
CarcinogensadmetSARNo-
ToxtreeNo-
Cramer's ruleToxtreeHigh (Class III)-
CytotoxicityvNNNo Prediction-
Genotoxic carcinogenityToxtreeNo-
HepatotoxicityadmetSARYes-
pkCSMNo-
vNNNo-
Human Ether-a-go-go-Related Gene InhibitoradmetSARNo
vNNNo-
Human Ether-a-go-go-Related Gene Inhibitor IpkCSMNo-
Human Ether-a-go-go-Related Gene Inhibitor IIpkCSMYes-
Mitochondrial Membrane Potential (MMP)vNNNo-
Maximum Recommended Tolerated Dose (MRTD)pkCSMLow0.447 mg/kg/day
vNN-1083 mg/day
Non-Genotoxic carcinogenicityToxtree-
Oral rat acute toxicitypkCSM-2.651 mol/kg (LD50)
pkCSM--0.349 mg/kg_bw/day (LOAEL)
MicronucleusadmetSARYes-
Skin sensitisationpkCSMNo-
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