Florfenicol

Florfenicol


Therapeutic actions reported: Antibacterial
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ⓘ Table glossary
Table glossary
ReferencePubMed ID of research paper
Experiment TypeIn vivo or in vitro
Cell / Tissue / Microbe / Strain If in vitro, cells = cells from aquaculture-relevant species
Cell / Tissue / Microbe / Strain If in vitro, tissues = tissues from aquaculture-relevant species
Cell / Tissue / Microbe / Strain If in vitro, microbes = type of microorganism obtained from aquaculture-relevant species
Cell / Tissue / Microbe / Strain If in vitro, strain = strain of microorganism obtained from aquaculture-relevant species
Cell / Tissue / Microbe / Strain If in vivo, this field is left blank
Test OrganismAquaculture-relevant species tested for prophylactic effect
LifestageLifestage of test organism if reported
Administration MethodRoute or method of chemical administration
Target OrganismPathogens affecting the test organism
Administered Dose RangeAll tested chemical doses
Significant Dose RangeDoses producing significant effects
Time to DeathTime to kill target organism (minutes)
Anthelminthic EfficacyEffectiveness in reducing target organism (%)
Therapeutic ActionReported therapeutic effect
Reference Experiment Type Cell/Tissue/Microbe/Strain Test Organism Lifestage Administration Method Target Organism Administered Dose Range Significant Dose Range Time to Death of Pathogen (min) Anthelminthic Efficacy (%) Therapeutic Action
PMID:33075142 In vitro Rs29 (From Atlantic salmon kidney; 2017) - - - Renibacterium salmoninarum 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro Rs30 (From Atlantic salmon kidney; 2018) - - - Renibacterium salmoninarum 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro Rs31 (From Atlantic salmon kidney; 2018) - - - Renibacterium salmoninarum 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro Rs32 (From Atlantic salmon kidney; 2018) - - - Renibacterium salmoninarum 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro Rs33 (From Atlantic salmon kidney; 2018) - - - Renibacterium salmoninarum 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro Rs34 (From Atlantic salmon kidney; 2018) - - - Renibacterium salmoninarum 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro Rs35 (From Atlantic salmon kidney; 2018) - - - Renibacterium salmoninarum 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro S-1 (From Coho salmon spleen; 2014) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro Rs28 (From Atlantic salmon kidney; 2017) - - - Renibacterium salmoninarum 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro Rs27 (From Atlantic salmon kidney; 2017) - - - Renibacterium salmoninarum 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro Rs26 (From Atlantic salmon kidney; 2017) - - - Renibacterium salmoninarum 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro Rs25 (From Atlantic salmon kidney; 2017) - - - Renibacterium salmoninarum 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro Rs07 (From Coho salmon kidney; 2013) - - - Renibacterium salmoninarum 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro Rs08 (From Atlantic salmon kidney; 2013) - - - Renibacterium salmoninarum 0.5
μg/mL		 0.5
μg/mL		 - - Antibacterial
In vitro Rs09 (From Atlantic salmon kidney; 2013) - - - Renibacterium salmoninarum 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro Rs10 (From Atlantic salmon kidney; 2013) - - - Renibacterium salmoninarum 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro Rs11 (From Atlantic salmon kidney; 2013) - - - Renibacterium salmoninarum 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro Rs12 (From Atlantic salmon kidney; 2015) - - - Renibacterium salmoninarum 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro Rs13 (From Atlantic salmon kidney; 2016) - - - Renibacterium salmoninarum 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro Rs15 (From Coho salmon kidney; 2016) - - - Renibacterium salmoninarum 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro Rs17 (From Atlantic salmon kidney; 2016) - - - Renibacterium salmoninarum 0.5
μg/mL		 0.5
μg/mL		 - - Antibacterial
In vitro Rs19 (From Atlantic salmon brain; 2016) - - - Renibacterium salmoninarum 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro Rs20 (From Atlantic salmon kidney; 2016) - - - Renibacterium salmoninarum 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro Rs21 (From Atlantic salmon kidney; 2016) - - - Renibacterium salmoninarum 0.5
μg/mL		 0.5
μg/mL		 - - Antibacterial
In vitro Rs22 (From Atlantic salmon liver; 2017) - - - Renibacterium salmoninarum 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro Rs23 (From Atlantic salmon kidney; 2017) - - - Renibacterium salmoninarum 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro Rs24 (From Atlantic salmon kidney; 2017) - - - Renibacterium salmoninarum 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro Rs16 (From Atlantic salmon kidney; 2016) - - - Renibacterium salmoninarum 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro Rs06 (From Coho salmon kidney; 2013) - - - Renibacterium salmoninarum 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro Rs05 (From Coho salmon kidney; 2013) - - - Renibacterium salmoninarum 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro Rs04 (From Coho salmon kidney; 2013) - - - Renibacterium salmoninarum 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro Rs03 (From Coho salmon kidney; 2013) - - - Renibacterium salmoninarum 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro H-13 (From Coho salmon liver; 2018) - - - Renibacterium salmoninarum 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro H-2 (From Atlantic salmon liver; 2014) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro H-7 (From Atlantic salmon liver; 2014) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro J7SP2R (From Atlantic salmon kidney; 2014) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro JSP2 (From Atlantic salmon kidney; 2014) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro R-1 (From Atlantic salmon kidney; 2014) - - - Renibacterium salmoninarum 8.0
μg/mL		 8.0
μg/mL		 - - Antibacterial
In vitro R-14 (From Coho salmon kidney; 2018) - - - Renibacterium salmoninarum 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro H-12 (From Coho salmon liver; 2018) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro R-15 (From Coho salmon kidney; 2018) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro R-17 (From Coho salmon kidney; 2018) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro R-19 (From Coho salmon kidney; 2018) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro R-3 (From Atlantic salmon kidney; 2014) - - - Renibacterium salmoninarum 8.0
μg/mL		 8.0
μg/mL		 - - Antibacterial
In vitro R-4 (From Coho salmon kidney; 2014) - - - Renibacterium salmoninarum 8.0
μg/mL		 8.0
μg/mL		 - - Antibacterial
In vitro R-8 (From Coho salmon kidney; 2015) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro Rs01 (From Coho salmon kidney; 2013) - - - Renibacterium salmoninarum 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro Rs02 (From Coho salmon kidney; 2013) - - - Renibacterium salmoninarum 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro R-16 (From Coho salmon kidney; 2018) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro DJ7R (From Atlantic salmon kidney; 2014) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro DJ2B (From Atlantic salmon spleen; 2014) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro DJ7B (From Atlantic salmon spleen; 2014) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro ATCC 25922 - - - Escherichia coli 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro ATCC 33658 - - - Aeromonas salmonicida 0.5
μg/mL		 0.5
μg/mL		 - - Antibacterial
In vitro B-2 (From Atlantic salmon spleen; 2014) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro B-3 (From Atlantic salmon spleen; 2014) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro B-4 (From Atlantic salmon spleen; 2014) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro BKD-2B (From Atlantic salmon kidney; 2017) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro BKD-4B (From Atlantic salmon kidney; 2017) - - - Renibacterium salmoninarum 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
PMID:35884183 In vitro Bacteria - - - Aeromonas hydrophila 2.5
μg/mL		 2.5
μg/mL		 - - Antibacterial
In vitro Bacteria - - Dosed with 1 µg/mL of Quercetin Aeromonas hydrophila 0.156
μg/mL		 0.156
μg/mL		 - - Antibacterial
In vivo - Cyprinus carpio - - Aeromonas hydrophila 2.5-10.0
mg/kg		 10.0
mg/kg		 - - Antibacterial
PMID:36857464 In vitro Bacteria - - - Edwardsiella ictaluri 1.1
μM		 1.1
μM		 - - Antibacterial
In vitro Bacteria - - - Streptococcus iniae 1.1
μM		 1.1
μM		 - - Antibacterial
In vitro Bacteria - - - Streptococcus parauberis 1.1
μM		 1.1
μM		 - - Antibacterial
PMID:38659458 In vitro LY21811 - - - Nocardia seriolae 30.0
µg/tablet		 30.0
µg/tablet		 - - Antibacterial
PMID:38835482 In vitro Bacteria - - - Flavobacterium columnare 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
PMID:39387133 In vitro ALM- 00- 173 - - - Flavobacterium covae 0.36-0.69
mg/L		 0.36-0.69
mg/L		 - - Antibacterial
PMID:40142452 In vitro - - - - Francisella orientalis 128.0
μg/mL		 128.0
μg/mL		 - - Antibacterial
In vitro Serotype III - - - Streptococcus agalactiae 5.0-128.0
μg/mL		 5.0-128.0
μg/mL		 - - Antibacterial
In vitro Serotype Ib - - - Streptococcus agalactiae 4.0-8.0
μg/mL		 4.0-8.0
μg/mL		 - - Antibacterial
In vivo - Oreochromis niloticus Juvenile Feed Francisella orientalis 10.0
mg/Kg		 10.0
mg/Kg		 - - Antibacterial
In vivo Serotype III Oreochromis niloticus Juvenile Feed Streptococcus agalactiae 10.0
mg/Kg		 10.0
mg/Kg		 - - Antibacterial
In vivo Serotype Ib Oreochromis niloticus Juvenile Feed Streptococcus agalactiae 10.0
mg/Kg		 10.0
mg/Kg		 - - Antibacterial
PMID:29741243 In vitro ATCC7966 - - - Aeromonas hydrophila 1.02-130.0
μg/mL		 1.02-130.0
μg/mL		 - - Antibacterial
In vitro MF 372510 - - - Aeromonas hydrophila 1.02-4.06
μg/mL		 1.02-4.06
μg/mL		 - - Antibacterial
In vitro MF372511 - - - Raoultella ornithinolytica 8.13-260.0
μg/mL		 8.13-260.0
μg/mL		 - - Antibacterial
In vitro MF565839 - - - Citrobacter freundii 8.13-260.0
μg/mL		 8.13-260.0
μg/mL		 - - Antibacterial
In vitro ATCC25922 - - - Escherichia coli 4.06-260.0
μg/mL		 4.06-260.0
μg/mL		 - - Antibacterial
PMID:30184134 In vitro Bacteria - - - Aeromonas hydrophila 5.0-200.0
μg/mL		 5.0
μg/mL		 - - Antibacterial
PMID:30735293 In vitro ATCC7966 - - - Aeromonas hydrophila 51.0
μg/mL		 51.0
μg/mL		 - - Antibacterial
In vitro MF372509 - - - Aeromonas hydrophila 51.0
μg/mL		 51.0
μg/mL		 - - Antibacterial
In vitro MF372509 - - - Raoultella ornithinolytica 203.0-325.0
μg/mL		 203.0-325.0
μg/mL		 - - Antibacterial
In vitro MF372511 - - - Citrobacter freundii 812.0-1300.0
μg/mL		 812.0-1300.0
μg/mL		 - - Antibacterial
In vitro MH397688 - - - Aeromonas veronii 25.0
μg/mL		 25.0
μg/mL		 - - Antibacterial
In vitro MH397689 - - - Aeromonas hydrophila 102.0
μg/mL		 102.0
μg/mL		 - - Antibacterial
In vivo MF 372510 Rhamdia quelen Juvenile - Aeromonas hydrophila 4.0
mg/l		 4.0
mg/l		 - - Antibacterial
In vitro MF372510 - - - Aeromonas hydrophila 51.0
μg/mL		 51.0
μg/mL		 - - Antibacterial
PMID:31614964 In vitro WS05 - - - Aeromonas hydrophila 0.5
mg/mL		 0.5
mg/mL		 - - Antibacterial
PMID:31905915 In vitro EA011113 - - - Edwardsiella anguillarum 0.24
μg/mL		 0.24
μg/mL		 - - Antibacterial
In vitro NS13 - - - Aeromonas veronii bv. sobria 0.26
μg/mL		 0.26
μg/mL		 - - Antibacterial
In vitro NS2 - - - Aeromonas veronii bv. sobria 0.36
μg/mL		 0.36
μg/mL		 - - Antibacterial
In vitro NS22 - - - Aeromonas veronii bv. sobria 0.3
μg/mL		 0.3
μg/mL		 - - Antibacterial
In vitro PdKef - - - Photobacterium damselae subsp. piscicida 0.33
μg/mL		 0.33
μg/mL		 - - Antibacterial
In vitro PDB - - - Aeromonas veronii bv. sobria 0.37
μg/mL		 0.37
μg/mL		 - - Antibacterial
In vitro V1 - - - Vibrio alginolyticus 0.53
μg/mL		 0.53
μg/mL		 - - Antibacterial
In vitro Vak - - - Vibrio anguillarum 0.46
μg/mL		 0.46
μg/mL		 - - Antibacterial
In vitro VhP1 - - - Vibrio harveyi 0.67
μg/mL		 0.67
μg/mL		 - - Antibacterial
PMID:29635710 In vitro ALM-00-173 - - - Flavobacterium columnare 1.0
mg/mL		 1.0
mg/mL		 - - Antibacterial
PMID:27190287 In vitro AUSTRAL-005 - - - Piscirickettsia salmonis 0.5-1.0
μg/mL		 0.5-1.0
μg/mL		 - - Antibacterial
In vitro LF-89 (ATCC VR-1361) - - - Piscirickettsia salmonis 0.25
μg/mL		 0.25
μg/mL		 - - Antibacterial
In vitro ATCC 25922 - - - Escherichia coli 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
PMID:14667023 In vitro Bacteria - - - Edwardsiella ictaluri 0.25
μg/mL		 0.25
μg/mL		 - - Antibacterial
PMID:20713674 In vitro ATCC 25922 - - - Escherichia coli 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro Isolated from Hybrid striped bass - - - Francisella sp. 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro LADL 07-285A - - - Francisella asiatica 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro LADL 07-285B - - - Francisella asiatica 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro THKDM - - - Francisella asiatica 1.0-100.0
μg/mL		 10.0-100.0
μg/mL		 - - Antibacterial
In vivo LADL 07-285A Oreochromis sp. Fingerling Feed Francisella asiatica 15.0
mg/kg/day		 15.0
mg/kg/day		 - - Antibacterial
In vitro - - - - Francisella victoria 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
PMID:32318593 In vitro ATCC 29213 - - - Streptococcus parauberis 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
In vitro KCTC 3651 - - - Streptococcus parauberis 0.5
μg/mL		 0.5
μg/mL		 - - Antibacterial
In vitro S177 - - - Streptococcus parauberis 4.0
μg/mL		 4.0
μg/mL		 - - Antibacterial
In vitro S1885 - - - Streptococcus parauberis 1.0
μg/mL		 1.0
μg/mL		 - - Antibacterial
In vitro Strain 2628 - - - Streptococcus parauberis 2.0
μg/mL		 2.0
μg/mL		 - - Antibacterial
PMID:32966864 In vitro Bacteria siolated from Colossoma macropomum - - - Aeromonas hydrophila 0.25-2.0
μg/mL		 0.25-2.0
μg/mL		 - - Antibacterial
ⓘ
Glossary ×
ReferencePubMed ID of research paper
Experiment TypeIn vivo or in vitro
Cell / Tissue / Microbe / Strain If in vitro, cells = cells from aquaculture-relevant species
Cell / Tissue / Microbe / Strain If in vitro, tissues = tissues from aquaculture-relevant species
Cell / Tissue / Microbe / Strain If in vitro, microbes = type of microorganism obtained from aquaculture-relevant species
Cell / Tissue / Microbe / Strain If in vitro, strain = strain of microorganism obtained from aquaculture-relevant species
Cell / Tissue / Microbe / Strain If in vivo, this field is left blank
Test OrganismAquaculture-relevant species tested for prophylactic effect
LifestageLifestage of test organism if reported
Administration MethodRoute or method of chemical administration
Target OrganismPathogens affecting the test organism
Administered Dose RangeAll tested chemical doses
Significant Dose RangeDoses producing significant effects
Time to DeathTime to kill target organism (minutes)
Anthelminthic EfficacyEffectiveness in reducing target organism (%)
Therapeutic ActionReported therapeutic effect
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ReCAnt is a database of chemicals used in aquaculture and their ecotoxic effects, compiled from published literature. The authors are not liable for any inaccuracies or omissions of any chemicals in this resource. Importantly, our sole goal to build this resource on chemicals used in aquaculture is to enable future basic research on this topic, and it does not necessarily reflect the views or objectives of our employers or funders.