Associated High Confidence AOPs |
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Associated AOPs with Level of Relevance 1
AOP Identifier |
AOP Title |
AO Classification |
OECD Status |
Coverage Score |
KE Identifier |
KE Name |
AOP:64 | Glucocorticoid Receptor (GR) Mediated Adult Leydig Cell Dysfunction Leading to Decreased Male Fertility | Reproductive System Disease | - | 0.14 | KE:520 | Decreased sperm quantity or quality in the adult, Decreased fertility |
AOP:136 | Intracellular Acidification Induced Olfactory Epithelial Injury Leading to Site of Contact Nasal Tumors | Benign Neoplasm; Respiratory System Disease | Under Review | 0.14 | KE:868 | Increase, Tissue Degeneration, Necrosis & Atrophy |
Associated AOPs with Level of Relevance 2
AOP Identifier |
AOP Title |
AO Classification |
OECD Status |
Coverage Score |
KE Identifier |
KE Name |
AOP:212 | Histone deacetylase inhibition leading to testicular atrophy | Reproductive System Disease | WPHA/WNT Endorsed | 0.17 | KE:1506 | Testicular atrophy |
AOP:322 | Alkylation of DNA leading to reduced sperm count | Reproductive System Disease | - | 0.2 | KE:1757 | Reduce, Sperm count |
No associated AOPs with Level of Relevance 3
No associated AOPs with Level of Relevance 5