For more information regarding the endpoints, refer to the 'ToxCast Endpoints' file on the
DOWNLOAD page.
ToxCast Endpoints for intended target type: RNA
| Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
|---|
| LTEA_HepaRG_CASP3 | Liver | 836 | CASP3 | P42574 | Activatory | 9.97 μM |
| LTEA_HepaRG_FOXO3 | Liver | 2309 | FOXO3 | O43524 | Activatory | 12.72 μM |
| LTEA_HepaRG_TP53 | Liver | 7157 | TP53 | P04637 | Activatory | 9.97 μM |
ToxCast Endpoints for intended target type: Protein
| Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
|---|
| CCTE_Deisenroth_AIME_384WELL_LUC_Inactive | Mammary Gland/Breast | 2099 | ESR1 | P03372 | Gain | 19.84 μM |
No ToxCast endpoints for intended target type: Molecular Messengers
ToxCast Endpoints for intended target type: Pathway
| Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
|---|
| TOX21_ERb_BLA_Agonist_ch2 | Kidney | | | | Gain | 13.82 μM |
ToxCast Endpoints for intended target type: Cellular
| Assay Name | Tissue | Response | AC50 value |
|---|
| BSK_hDFCGF_Proliferation | Skin | Inhibitory | 20.10 μM |
No ToxCast endpoints for intended target type: Extracellular
