For more information regarding the endpoints, refer to the 'ToxCast Endpoints' file on the
DOWNLOAD page.
ToxCast Endpoints for intended target type: RNA
Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
---|
LTEA_HepaRG_CYP1A1 | Liver | 1543 | CYP1A1 | P04798 | Activatory | 35.08 μM |
LTEA_HepaRG_CYP2B6 | Liver | 1555 | CYP2B6 | P20813 | Activatory | 50.00 μM |
ToxCast Endpoints for intended target type: Protein
Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
---|
CCTE_Deisenroth_AIME_384WELL_LUC_Active | Mammary Gland/Breast | 2099 | ESR1 | P03372 | Gain | 33.95 μM |
CCTE_Deisenroth_AIME_384WELL_LUC_Inactive | Mammary Gland/Breast | 2099 | ESR1 | P03372 | Gain | 43.51 μM |
CCTE_Deisenroth_AIME_384WELL_LUC_Shift | Mammary Gland/Breast | 2099 | ESR1 | P03372 | Inhibitory | 23.78 μM |
ERF_TW_NR_binding_hAR | | 367 | AR | P10275 | Gain | 22.16 μM |
BSK_CASM3C_SAA | Vascular | 6288 | SAA1 | P0DJI8 | Activatory | 20.00 μM |
TOX21_p450_CYP1A2_Antagonist | | 1544 | CYP1A2 | P05177 | Loss | 23.26 μM |
TOX21_ERR_LUC_Antagonist | Kidney | 2101 | ESRRA | P11474 | Loss | 46.95 μM |
TOX21_p450_CYP1A2_Antagonist | | 1544 | CYP1A2 | P05177 | Loss | 49.14 μM |
No ToxCast endpoints for intended target type: Molecular Messengers
No ToxCast endpoints for intended target type: Pathway
No ToxCast endpoints for intended target type: Cellular
No ToxCast endpoints for intended target type: Extracellular