For more information regarding the endpoints, refer to the 'ToxCast Endpoints' file on the
DOWNLOAD page.
No ToxCast endpoints for intended target type: RNA
ToxCast Endpoints for intended target type: Protein
Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
---|
CCTE_Deisenroth_AIME_384WELL_CTox_Inactive | Mammary Gland/Breast | | | | Loss | 100.00 μM |
CCTE_GLTED_hIYD | | 389434 | IYD | | Loss | 151.98 μM |
ATG_PXRE_CIS | Liver | 8856 | NR1I2 | O75469 | Activatory | 1.67 μM |
ATG_ERa_TRANS | Liver | 2099 | ESR1 | P03372 | Gain | 4.92 μM |
ATG_PXR_TRANS | Liver | 8856 | NR1I2 | O75469 | Gain | 1.05 μM |
NVS_NR_hPXR | | 8856 | NR1I2 | O75469 | Loss | 0.43 μM |
NVS_NR_hRAR_Antagonist | | 5914 | RARA | P10276 | Loss | 6.24 μM |
No ToxCast endpoints for intended target type: Molecular Messengers
ToxCast Endpoints for intended target type: Pathway
Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
---|
ACEA_AR_antagonist_80hr | Prostate | 367 | AR | P10275 | Loss | 6.77 μM |
ToxCast Endpoints for intended target type: Cellular
Assay Name | Tissue | Response | AC50 value |
---|
ACEA_AR_agonist_AUC_viability | Prostate | Loss | 3.43 μM |
ACEA_AR_antagonist_AUC_viability | Prostate | Loss | 3.41 μM |
TOX21_ERR_LUC_viability | Kidney | Loss | 6.94 μM |
TOX21_PXR_LUC_Agonist_viability | Liver | Loss | 7.43 μM |
No ToxCast endpoints for intended target type: Extracellular