For more information regarding the endpoints, refer to the 'ToxCast Endpoints' file on the
DOWNLOAD page.
No ToxCast endpoints for intended target type: RNA
ToxCast Endpoints for intended target type: Protein
Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
---|
TOX21_AR_BLA_Agonist_ratio | Kidney | 367 | AR | P10275 | Gain | 2.59 μM |
TOX21_VDR_BLA_Agonist_ch2 | Kidney | | | | Gain | 2.17 μM |
TOX21_p450_CYP1A2_Antagonist | | 1544 | CYP1A2 | P05177 | Loss | 0.18 μM |
No ToxCast endpoints for intended target type: Molecular Messengers
ToxCast Endpoints for intended target type: Pathway
Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
---|
TOX21_AR_BLA_Agonist_ch2 | Kidney | | | | Gain | 2.72 μM |
TOX21_GR_BLA_Agonist_ch2 | Cervix | | | | Gain | 2.54 μM |
TOX21_ARE_BLA_Agonist_ch2 | Liver | | | | Gain | 2.88 μM |
TOX21_ARE_BLA_Agonist_ratio | Liver | 4780 | NFE2L2 | Q16236 | Gain | 3.00 μM |
TOX21_p53_BLA_p1_ch2 | Intestinal | | | | Gain | 2.44 μM |
TOX21_PPARd_BLA_Agonist_ch2 | Kidney | | | | Gain | 2.39 μM |
TOX21_PPARd_BLA_Agonist_ratio | Kidney | 5467 | PPARD | Q03181 | Gain | 2.43 μM |
TOX21_p53_BLA_p2_ch2 | Intestinal | | | | Gain | 1.94 μM |
TOX21_p53_BLA_p2_ratio | Intestinal | 7157 | TP53 | P04637 | Gain | 1.94 μM |
TOX21_p53_BLA_p5_ch2 | Intestinal | | | | Gain | 2.67 μM |
TOX21_p53_BLA_p5_ratio | Intestinal | 7157 | TP53 | P04637 | Gain | 2.79 μM |
TOX21_ESRE_BLA_Agonist_ch2 | Cervix | | | | Gain | 2.33 μM |
TOX21_ESRE_BLA_Agonist_ratio | Cervix | 22926 | ATF6 | P18850 | Gain | 2.38 μM |
TOX21_NFkB_BLA_agonist_ch2 | Cervix | | | | Gain | 2.57 μM |
No ToxCast endpoints for intended target type: Cellular
No ToxCast endpoints for intended target type: Extracellular