For more information regarding the endpoints, refer to the 'ToxCast Endpoints' file on the
DOWNLOAD page.
No ToxCast endpoints for intended target type: RNA
ToxCast Endpoints for intended target type: Protein
Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
---|
TOX21_AhR_LUC_Agonist | Liver | 196 | AHR | P35869 | Gain | 2.06 μM |
TOX21_ERR_LUC_Agonist | Kidney | 2101 | ESRRA | P11474 | Gain | 0.95 μM |
TOX21_PGC_ERR_LUC_Agonist | Kidney | 2101 | ESRRA | P11474 | Gain | 2.14 μM |
TOX21_PR_BLA_Antagonist_ratio | Kidney | 5241 | PGR | P06401 | Loss | 2.15 μM |
TOX21_p450_CYP1A2_Antagonist | | 1544 | CYP1A2 | P05177 | Loss | 0.67 μM |
No ToxCast endpoints for intended target type: Molecular Messengers
ToxCast Endpoints for intended target type: Pathway
Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
---|
TOX21_ARE_BLA_Agonist_ch2 | Liver | | | | Gain | 21.76 μM |
TOX21_ARE_BLA_Agonist_ratio | Liver | 4780 | NFE2L2 | Q16236 | Gain | 21.76 μM |
TOX21_HDAC_LUC_Antagonist | Colon | 3065 | HDAC1 | Q13547 | Loss | 7.28 μM |
No ToxCast endpoints for intended target type: Cellular
No ToxCast endpoints for intended target type: Extracellular