For more information regarding the endpoints, refer to the 'ToxCast Endpoints' file on the
DOWNLOAD page.
ToxCast Endpoints for intended target type: RNA
| Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
|---|
| CLD_HMGCS2_48hr | Liver | 3158 | HMGCS2 | P54868 | Gain | 0.01 μM |
| LTEA_HepaRG_BID | Liver | 637 | BID | P55957 | Inhibitory | 10.12 μM |
| LTEA_HepaRG_GADD45A | Liver | 1647 | GADD45A | P24522 | Inhibitory | 10.12 μM |
| LTEA_HepaRG_TIMP1 | Liver | 7076 | TIMP1 | P01033 | Inhibitory | 10.12 μM |
| LTEA_HepaRG_TNFRSF1A | Liver | 7132 | TNFRSF1A | P19438 | Inhibitory | 10.12 μM |
| LTEA_HepaRG_FOXO3 | Liver | 2309 | FOXO3 | O43524 | Activatory | 0.07 μM |
| LTEA_HepaRG_LPL | Liver | 4023 | LPL | P06858 | Activatory | 0.09 μM |
ToxCast Endpoints for intended target type: Protein
| Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
|---|
| CPHEA_Stoker_NIS_Inhibition_RAIU | Kidney | 6528 | SLC5A5 | Q92911 | Loss | 0.29 μM |
| CPHEA_Stoker_NIS_Inhibition_RAIU | Kidney | 6528 | SLC5A5 | Q92911 | Loss | 6.66 μM |
| ATG_Ahr_CIS | Liver | 196 | AHR | P35869 | Activatory | 5.97 μM |
| ATG_AP_1_CIS | Liver | 3725|2353 | JUN|FOS | P01100|P05412 | Activatory | 8.94 μM |
| ATG_BRE_CIS | Liver | 4086 | SMAD1 | Q15797 | Activatory | 5.97 μM |
| ATG_CMV_CIS | Liver | | | | Activatory | 8.95 μM |
| ATG_CRE_CIS | Liver | 10488 | CREB3 | O43889 | Activatory | 8.78 μM |
| ATG_DR5_RAR_CIS | Liver | 5916|5915|5914 | RARG|RARB|RARA | P10826|P10276|P13631 | Activatory | 5.97 μM |
| ATG_Ets_CIS | Liver | 2113 | ETS1 | P14921 | Inhibitory | 5.97 μM |
| ATG_GATA_CIS | Liver | 2623 | GATA1 | P15976 | Inhibitory | 5.97 μM |
| ATG_HSE_CIS | Liver | 3297 | HSF1 | Q00613 | Activatory | 9.05 μM |
| ATG_Myc_CIS | Liver | 4609 | MYC | P01106 | Activatory | 10.59 μM |
| ATG_NFI_CIS | Liver | 4774 | NFIA | Q12857 | Activatory | 5.97 μM |
| ATG_NRF2_ARE_CIS | Liver | 4780 | NFE2L2 | Q16236 | Activatory | 5.97 μM |
| ATG_PPRE_CIS | Liver | 5468|5467|5465 | PPARG|PPARD|PPARA | P37231|Q07869|Q03181 | Activatory | 5.97 μM |
| ATG_PXRE_CIS | Liver | 8856 | NR1I2 | O75469 | Activatory | 1.84 μM |
| ATG_Sox_CIS | Liver | 6656 | SOX1 | O00570 | Activatory | 10.25 μM |
| ATG_Sp1_CIS | Liver | 6667 | SP1 | P08047 | Activatory | 8.52 μM |
| ATG_Xbp1_CIS | Liver | 7494 | XBP1 | P17861 | Activatory | 10.04 μM |
| ATG_PPARg_TRANS | Liver | 5468 | PPARG | P37231 | Gain | 5.97 μM |
| ATG_PXR_TRANS | Liver | 8856 | NR1I2 | O75469 | Gain | 5.97 μM |
| ATG_RXRb_TRANS | Liver | 6257 | RXRB | P28702 | Gain | 4.25 μM |
| CCTE_GLTED_hTBG | | 6906 | SERPINA7 | | Loss | 0.15 μM |
| CCTE_GLTED_hTTR_0.125uM | | 7276 | TTR | | Loss | 0.22 μM |
| NVS_ADME_hCYP2C19 | | 1557 | CYP2C19 | P33261 | Loss | 10.00 μM |
| NVS_ADME_hCYP2C8 | | 1558 | CYP2C8 | P10632 | Loss | 4.51 μM |
| NVS_ADME_hCYP2C9 | | 1559 | CYP2C9 | P11712 | Loss | 8.05 μM |
| NVS_ENZ_hBACE | | 23621 | BACE1 | P56817 | Loss | 7.92 μM |
| NVS_GPCR_hOpiate_D1 | | 4985 | OPRD1 | P41143 | Loss | 9.39 μM |
| NVS_NR_hAR | | 367 | AR | P10275 | Loss | 8.17 μM |
| NVS_TR_hNET | | 6530 | SLC6A2 | P23975 | Loss | 0.49 μM |
| NVS_NR_hPPARg | | 5468 | PPARG | P37231 | Loss | 6.67 μM |
| BSK_3C_uPAR | Vascular | 5329 | PLAUR | Q03405 | Inhibitory | 9.81 μM |
| BSK_4H_VEGFRII | Vascular | 3791 | KDR | P35968 | Inhibitory | 9.59 μM |
| BSK_CASM3C_Thrombomodulin | Vascular | 7056 | THBD | P07204 | Activatory | 4.67 μM |
| BSK_hDFCGF_CollagenIII | Skin | 1281 | COL3A1 | P02461 | Inhibitory | 8.82 μM |
| BSK_hDFCGF_EGFR | Skin | 1956 | EGFR | P00533 | Inhibitory | 5.46 μM |
| BSK_hDFCGF_PAI1 | Skin | 5054 | SERPINE1 | P05121 | Inhibitory | 7.44 μM |
| BSK_hDFCGF_VCAM1 | Skin | 7412 | VCAM1 | P19320 | Inhibitory | 9.14 μM |
| BSK_KF3CT_SRB | Skin | | | | Inhibitory | 10.48 μM |
| BSK_LPS_PGE2 | Vascular | 5732 | PTGER2 | P43116 | Inhibitory | 5.48 μM |
| BSK_SAg_Eselectin | Vascular | 6401 | SELE | P16581 | Inhibitory | 10.85 μM |
| ATG_AP_1_CIS | Liver | 3725|2353 | JUN|FOS | P01100|P05412 | Activatory | 8.30 μM |
| ATG_BRE_CIS | Liver | 4086 | SMAD1 | Q15797 | Activatory | 7.53 μM |
| ATG_CRE_CIS | Liver | 10488 | CREB3 | O43889 | Activatory | 8.07 μM |
| ATG_EGR_CIS | Liver | 1958 | EGR1 | P18146 | Activatory | 8.36 μM |
| ATG_ISRE_CIS | Liver | 3659 | IRF1 | P10914 | Inhibitory | 8.46 μM |
| ATG_NRF2_ARE_CIS | Liver | 4780 | NFE2L2 | Q16236 | Activatory | 8.17 μM |
| ATG_Pax6_CIS | Liver | 5080 | PAX6 | P26367 | Activatory | 8.60 μM |
| ATG_PXRE_CIS | Liver | 8856 | NR1I2 | O75469 | Activatory | 3.06 μM |
| ATG_VDRE_CIS | Liver | 7421 | VDR | P11473 | Activatory | 8.06 μM |
| ATG_ERa_TRANS | Liver | 2099 | ESR1 | P03372 | Gain | 6.47 μM |
| ATG_PXR_TRANS | Liver | 8856 | NR1I2 | O75469 | Gain | 5.64 μM |
| ATG_RXRb_TRANS | Liver | 6257 | RXRB | P28702 | Gain | 7.45 μM |
| NVS_ADME_hCYP2C19 | | 1557 | CYP2C19 | P33261 | Loss | 2.82 μM |
| NVS_GPCR_hOpiate_mu | | 4988 | OPRM1 | P35372 | Loss | 7.86 μM |
| NVS_NR_hAR | | 367 | AR | P10275 | Loss | 9.19 μM |
| NVS_TR_hNET | | 6530 | SLC6A2 | P23975 | Loss | 0.91 μM |
| ATG_BRE_CIS | Liver | 4086 | SMAD1 | Q15797 | Activatory | 4.12 μM |
| ATG_CRE_CIS | Liver | 10488 | CREB3 | O43889 | Activatory | 5.31 μM |
| ATG_NRF2_ARE_CIS | Liver | 4780 | NFE2L2 | Q16236 | Activatory | 3.29 μM |
| ATG_Oct_MLP_CIS | Liver | 5451 | POU2F1 | P14859 | Activatory | 7.17 μM |
| ATG_PBREM_CIS | Liver | 9970 | NR1I3 | Q14994 | Activatory | 3.38 μM |
| ATG_PPRE_CIS | Liver | 5468|5467|5465 | PPARG|PPARD|PPARA | P37231|Q07869|Q03181 | Activatory | 5.08 μM |
| ATG_PXRE_CIS | Liver | 8856 | NR1I2 | O75469 | Activatory | 3.06 μM |
| ATG_VDRE_CIS | Liver | 7421 | VDR | P11473 | Activatory | 4.19 μM |
| ATG_PXR_TRANS | Liver | 8856 | NR1I2 | O75469 | Gain | 3.52 μM |
| ATG_RXRb_TRANS | Liver | 6257 | RXRB | P28702 | Gain | 5.44 μM |
| BSK_3C_SRB | Vascular | | | | Inhibitory | 10.12 μM |
| BSK_3C_uPAR | Vascular | 5329 | PLAUR | Q03405 | Inhibitory | 8.24 μM |
| BSK_4H_MCP1 | Vascular | 6347 | CCL2 | P13500 | Inhibitory | 9.60 μM |
| BSK_4H_Pselectin | Vascular | 6403 | SELP | P16109 | Inhibitory | 10.64 μM |
| BSK_4H_VCAM1 | Vascular | 7412 | VCAM1 | P19320 | Inhibitory | 10.40 μM |
| BSK_4H_VEGFRII | Vascular | 3791 | KDR | P35968 | Inhibitory | 6.66 μM |
| BSK_hDFCGF_CollagenIII | Skin | 1281 | COL3A1 | P02461 | Inhibitory | 5.45 μM |
| BSK_hDFCGF_IP10 | Skin | 3627 | CXCL10 | P02778 | Inhibitory | 9.41 μM |
| BSK_hDFCGF_MCSF | Skin | 1435 | CSF1 | P09603 | Inhibitory | 10.70 μM |
| BSK_hDFCGF_PAI1 | Skin | 5054 | SERPINE1 | P05121 | Inhibitory | 8.43 μM |
| BSK_hDFCGF_SRB | Skin | | | | Inhibitory | 10.59 μM |
| BSK_hDFCGF_VCAM1 | Skin | 7412 | VCAM1 | P19320 | Inhibitory | 8.72 μM |
| BSK_LPS_PGE2 | Vascular | 5732 | PTGER2 | P43116 | Inhibitory | 5.59 μM |
| NVS_ADME_hCYP1A2 | | 1544 | CYP1A2 | P05177 | Loss | 9.33 μM |
| NVS_ADME_hCYP2C19 | | 1557 | CYP2C19 | P33261 | Loss | 2.10 μM |
| NVS_ADME_hCYP2C9 | | 1559 | CYP2C9 | P11712 | Loss | 7.15 μM |
| NVS_NR_hAR | | 367 | AR | P10275 | Loss | 8.33 μM |
| NVS_TR_hNET | | 6530 | SLC6A2 | P23975 | Loss | 0.59 μM |
| NVS_ADME_hCYP2C19 | | 1557 | CYP2C19 | P33261 | Loss | 2.43 μM |
| NVS_ADME_hCYP2C9 | | 1559 | CYP2C9 | P11712 | Loss | 4.99 μM |
| NVS_GPCR_hAdra2C | | 152 | ADRA2C | P18825 | Loss | 6.80 μM |
| NVS_NR_hAR | | 367 | AR | P10275 | Loss | 10.45 μM |
| NVS_TR_hNET | | 6530 | SLC6A2 | P23975 | Loss | 0.55 μM |
| ATG_BRE_CIS | Liver | 4086 | SMAD1 | Q15797 | Activatory | 7.53 μM |
| ATG_CMV_CIS | Liver | | | | Activatory | 7.09 μM |
| ATG_EGR_CIS | Liver | 1958 | EGR1 | P18146 | Activatory | 7.91 μM |
| ATG_NRF2_ARE_CIS | Liver | 4780 | NFE2L2 | Q16236 | Activatory | 7.49 μM |
| ATG_Oct_MLP_CIS | Liver | 5451 | POU2F1 | P14859 | Activatory | 9.73 μM |
| ATG_PXRE_CIS | Liver | 8856 | NR1I2 | O75469 | Activatory | 3.11 μM |
| ATG_VDRE_CIS | Liver | 7421 | VDR | P11473 | Activatory | 8.24 μM |
| ATG_AP_1_CIS | Liver | 3725|2353 | JUN|FOS | P01100|P05412 | Activatory | 7.48 μM |
| ATG_BRE_CIS | Liver | 4086 | SMAD1 | Q15797 | Activatory | 7.15 μM |
| ATG_CMV_CIS | Liver | | | | Activatory | 9.27 μM |
| ATG_NRF2_ARE_CIS | Liver | 4780 | NFE2L2 | Q16236 | Activatory | 8.30 μM |
| ATG_Oct_MLP_CIS | Liver | 5451 | POU2F1 | P14859 | Activatory | 9.80 μM |
| ATG_PXRE_CIS | Liver | 8856 | NR1I2 | O75469 | Activatory | 2.89 μM |
| ATG_VDRE_CIS | Liver | 7421 | VDR | P11473 | Activatory | 7.83 μM |
| ATG_Xbp1_CIS | Liver | 7494 | XBP1 | P17861 | Activatory | 8.35 μM |
| ATG_PXR_TRANS | Liver | 8856 | NR1I2 | O75469 | Gain | 6.27 μM |
| ATG_RXRb_TRANS | Liver | 6257 | RXRB | P28702 | Gain | 8.68 μM |
| BSK_3C_SRB | Vascular | | | | Inhibitory | 10.20 μM |
| BSK_3C_TissueFactor | Vascular | 2152 | F3 | P13726 | Inhibitory | 8.51 μM |
| BSK_4H_VEGFRII | Vascular | 3791 | KDR | P35968 | Inhibitory | 5.24 μM |
| BSK_hDFCGF_CollagenIII | Skin | 1281 | COL3A1 | P02461 | Inhibitory | 4.60 μM |
| BSK_hDFCGF_IP10 | Skin | 3627 | CXCL10 | P02778 | Inhibitory | 9.29 μM |
| BSK_hDFCGF_MCSF | Skin | 1435 | CSF1 | P09603 | Inhibitory | 7.83 μM |
| BSK_hDFCGF_PAI1 | Skin | 5054 | SERPINE1 | P05121 | Inhibitory | 6.96 μM |
| BSK_hDFCGF_SRB | Skin | | | | Inhibitory | 9.31 μM |
| BSK_hDFCGF_VCAM1 | Skin | 7412 | VCAM1 | P19320 | Inhibitory | 7.40 μM |
| BSK_LPS_CD40 | Vascular | 958 | CD40 | P25942 | Inhibitory | 9.21 μM |
| BSK_LPS_PGE2 | Vascular | 5732 | PTGER2 | P43116 | Inhibitory | 6.07 μM |
| BSK_SAg_CD40 | Vascular | 958 | CD40 | P25942 | Inhibitory | 10.89 μM |
| BSK_SAg_IL8 | Vascular | 3576 | CXCL8 | P10145 | Inhibitory | 9.94 μM |
| BSK_3C_SRB | Vascular | | | | Inhibitory | 10.81 μM |
| BSK_CASM3C_IL6 | Vascular | 3569 | IL6 | P05231 | Inhibitory | 0.56 μM |
| BSK_hDFCGF_CollagenIII | Skin | 1281 | COL3A1 | P02461 | Inhibitory | 7.46 μM |
| BSK_hDFCGF_EGFR | Skin | 1956 | EGFR | P00533 | Inhibitory | 5.45 μM |
| BSK_hDFCGF_MCSF | Skin | 1435 | CSF1 | P09603 | Inhibitory | 9.31 μM |
| BSK_hDFCGF_VCAM1 | Skin | 7412 | VCAM1 | P19320 | Inhibitory | 5.67 μM |
| BSK_LPS_PGE2 | Vascular | 5732 | PTGER2 | P43116 | Inhibitory | 7.30 μM |
| NVS_ADME_hCYP2C9 | | 1559 | CYP2C9 | P11712 | Loss | 4.20 μM |
| NVS_GPCR_hOpiate_D1 | | 4985 | OPRD1 | P41143 | Loss | 10.75 μM |
| ATG_Ets_CIS | Liver | 2113 | ETS1 | P14921 | Inhibitory | 7.09 μM |
| ATG_NRF2_ARE_CIS | Liver | 4780 | NFE2L2 | Q16236 | Activatory | 3.10 μM |
| ATG_Oct_MLP_CIS | Liver | 5451 | POU2F1 | P14859 | Activatory | 6.31 μM |
| ATG_PBREM_CIS | Liver | 9970 | NR1I3 | Q14994 | Activatory | 2.91 μM |
| ATG_PXRE_CIS | Liver | 8856 | NR1I2 | O75469 | Activatory | 2.94 μM |
| ATG_Sp1_CIS | Liver | 6667 | SP1 | P08047 | Activatory | 4.75 μM |
| ATG_VDRE_CIS | Liver | 7421 | VDR | P11473 | Activatory | 3.01 μM |
| ATG_PXR_TRANS | Liver | 8856 | NR1I2 | O75469 | Gain | 6.10 μM |
| ATG_RXRb_TRANS | Liver | 6257 | RXRB | P28702 | Gain | 6.57 μM |
| ATG_BRE_CIS | Liver | 4086 | SMAD1 | Q15797 | Activatory | 5.42 μM |
| ATG_CMV_CIS | Liver | | | | Activatory | 6.64 μM |
| ATG_CRE_CIS | Liver | 10488 | CREB3 | O43889 | Activatory | 6.80 μM |
| ATG_NRF2_ARE_CIS | Liver | 4780 | NFE2L2 | Q16236 | Activatory | 5.63 μM |
| ATG_Oct_MLP_CIS | Liver | 5451 | POU2F1 | P14859 | Activatory | 8.19 μM |
| ATG_p53_CIS | Liver | 7157 | TP53 | P04637 | Inhibitory | 7.73 μM |
| ATG_PPRE_CIS | Liver | 5468|5467|5465 | PPARG|PPARD|PPARA | P37231|Q07869|Q03181 | Activatory | 7.31 μM |
| ATG_PXRE_CIS | Liver | 8856 | NR1I2 | O75469 | Activatory | 2.98 μM |
| ATG_VDRE_CIS | Liver | 7421 | VDR | P11473 | Activatory | 8.30 μM |
| ATG_PXR_TRANS | Liver | 8856 | NR1I2 | O75469 | Gain | 4.06 μM |
| ATG_RXRb_TRANS | Liver | 6257 | RXRB | P28702 | Gain | 8.64 μM |
| CPHEA_Stoker_NIS_Inhibition_RAIU | Kidney | 6528 | SLC5A5 | Q92911 | Loss | 10.45 μM |
| CPHEA_Stoker_NIS_Inhibition_RAIU | Kidney | 6528 | SLC5A5 | Q92911 | Loss | 9.08 μM |
| CPHEA_Stoker_NIS_Inhibition_RAIU | Kidney | 6528 | SLC5A5 | Q92911 | Loss | 8.69 μM |
| ATG_zfER2a_XSP1 | Liver | 317734 | esr2a | Q7ZU32 | Gain | 4.96 μM |
| ATG_frER2_XSP1 | Liver | 100174814 | esr2.L | A0A1L8FA50 | Gain | 7.05 μM |
| ATG_hERa_XSP1 | Liver | 2099 | ESR1 | P03372 | Gain | 8.52 μM |
| ATG_trERa_XSP1 | Liver | 101933533 | ESR1 | B6E1V9 | Gain | 5.85 μM |
| ATG_hPPARg_XSP1 | Liver | 5468 | PPARG | P37231 | Gain | 9.39 μM |
| ATG_hTRa_XSP1 | Liver | 7067 | THRA | P10827 | Gain | 7.06 μM |
| ATG_chERa_XSP2 | Liver | 396099 | ESR1 | P06212 | Gain | 7.48 μM |
| ATG_hERa_XSP2 | Liver | 2099 | ESR1 | P03372 | Gain | 8.98 μM |
| ATG_trTRa_XSP2 | Liver | 101949057 | | | Gain | 4.84 μM |
| ATG_frTRa_XSP2 | Liver | 397942 | thra.L | P15204 | Gain | 2.46 μM |
| ATG_hTRb_XSP2 | Liver | 7068 | THRB | P10828 | Gain | 4.77 μM |
| CPHEA_Stoker_NIS_Inhibition_RAIU | Kidney | 6528 | SLC5A5 | Q92911 | Loss | 7.59 μM |
| CPHEA_Stoker_NIS_Inhibition_RAIU | Kidney | 6528 | SLC5A5 | Q92911 | Loss | 9.92 μM |
| TOX21_p450_CYP2C19_Antagonist | | 1557 | CYP2C19 | P33261 | Loss | 0.74 μM |
| TOX21_p450_CYP2C9_Antagonist | | 1559 | CYP2C9 | P11712 | Loss | 4.43 μM |
| TOX21_p450_CYP2C19_Antagonist | | 1557 | CYP2C19 | P33261 | Loss | 0.78 μM |
| TOX21_p450_CYP2C9_Antagonist | | 1559 | CYP2C9 | P11712 | Loss | 4.64 μM |
No ToxCast endpoints for intended target type: Molecular Messengers
ToxCast Endpoints for intended target type: Pathway
| Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
|---|
| APR_HepG2_CellCycleArrest_1hr | Liver | | | | Inhibitory | 118.13 μM |
| APR_HepG2_CellCycleArrest_24hr | Liver | | | | Inhibitory | 9.18 μM |
| OT_AR_ARSRC1_0960 | Kidney | 6714|367 | AR|SRC | P12931|P10275 | Gain | 4.47 μM |
ToxCast Endpoints for intended target type: Cellular
| Assay Name | Tissue | Response | AC50 value |
|---|
| APR_HepG2_MitoMass_1hr | Liver | Inhibitory | 169.68 μM |
| APR_HepG2_NuclearSize_1hr | Liver | Inhibitory | 157.54 μM |
| APR_HepG2_MitoMembPot_24hr | Liver | Inhibitory | 4.39 μM |
| BSK_3C_Proliferation | Vascular | Inhibitory | 9.80 μM |
| BSK_hDFCGF_Proliferation | Skin | Inhibitory | 4.30 μM |
| BSK_SAg_Proliferation | Vascular | Inhibitory | 6.76 μM |
| BSK_3C_Proliferation | Vascular | Inhibitory | 8.28 μM |
| BSK_3C_Vis | Vascular | Inhibitory | 7.96 μM |
| BSK_hDFCGF_Proliferation | Skin | Inhibitory | 4.61 μM |
| BSK_SAg_Proliferation | Vascular | Inhibitory | 8.84 μM |
| APR_HepG2_MitoMass_24hr | Liver | Activatory | 176.80 μM |
| APR_HepG2_MitoMass_72hr | Liver | Activatory | 170.25 μM |
| BSK_hDFCGF_Proliferation | Skin | Inhibitory | 4.42 μM |
| BSK_SAg_Proliferation | Vascular | Inhibitory | 8.15 μM |
| BSK_hDFCGF_Proliferation | Skin | Inhibitory | 4.78 μM |
| BSK_SAg_Proliferation | Vascular | Inhibitory | 8.46 μM |
| CEETOX_H295R_MTT_cell_viability | Adrenal Gland | Activatory | 0.02 μM |
| VALA_TUBIPS_Agonist_CellCount | Ips-Derived Endothelial Cells | Loss | 7.53 μM |
| VALA_TUBIPS_Antagonist_CellCount | Ips-Derived Endothelial Cells | Loss | 0.01 μM |
| CCTE_Simmons_CellTiterGLO_HEK293T | Kidney | Loss | 8.94 μM |
| CCTE_Simmons_CellTiterGLO_HEK293T | Kidney | Loss | 9.19 μM |
| CPHEA_Stoker_NIS_Cytotoxicity | Kidney | Loss | 9.92 μM |
| TOX21_MMP_rhodamine | Liver | Loss | 4.70 μM |
| TOX21_MMP_ratio | Liver | Inhibitory | 4.85 μM |
| TOX21_PPARd_BLA_Agonist_viability | Kidney | Loss | 7.48 μM |
| TOX21_MMP_rhodamine | Liver | Loss | 1.56 μM |
| TOX21_MMP_ratio | Liver | Inhibitory | 1.48 μM |
No ToxCast endpoints for intended target type: Extracellular
