ToxCast Endpoints
For more information regarding the endpoints, refer to the 'ToxCast Endpoints' file on the DOWNLOAD page.

ToxCast Endpoints for intended target type: RNA
Assay NameTissueTarget Gene IDTarget HGNC SymbolTarget UniProt IDResponseAC50 value
LTEA_HepaRG_CYP1A1Liver1543CYP1A1P04798Activatory76.62 μM
LTEA_HepaRG_CYP1A2Liver1544CYP1A2P05177Activatory50.00 μM
LTEA_HepaRG_CYP2B6Liver1555CYP2B6P20813Inhibitory0.10 μM

ToxCast Endpoints for intended target type: Protein
Assay NameTissueTarget Gene IDTarget HGNC SymbolTarget UniProt IDResponseAC50 value
TOX21_p450_CYP2D6_Antagonist1565CYP2D6P10635Loss107.98 μM

No ToxCast endpoints for intended target type: Molecular Messengers

No ToxCast endpoints for intended target type: Pathway

ToxCast Endpoints for intended target type: Cellular
Assay NameTissueResponseAC50 value
APR_HepG2_CellLoss_72hrLiverInhibitory61.44 μM

No ToxCast endpoints for intended target type: Extracellular
DISCLAIMER

TICToK is a database of tattoo ink chemicals compiled from different regulatory resources. The authors are not liable for any inaccuracies or omissions of any chemicals in this resource. Importantly, our sole goal to build this resource on tattoo ink chemicals is to enable future basic research on this topic, and it does not necessarily reflect the views or objectives of our employers or funders.