For more information regarding the endpoints, refer to the 'ToxCast Endpoints' file on the
DOWNLOAD page.
No ToxCast endpoints for intended target type: RNA
ToxCast Endpoints for intended target type: Protein
Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
---|
ATG_NRF2_ARE_CIS | Liver | 4780 | NFE2L2 | Q16236 | Activatory | 61.20 mg/l |
ATG_PPARg_TRANS | Liver | 5468 | PPARG | P37231 | Gain | 22.83 mg/l |
NVS_NR_hPXR | | 8856 | NR1I2 | O75469 | Loss | 1.07 mg/l |
TOX21_Aromatase_LUC_Antagonist | Breast | 1588 | CYP19A1 | P11511 | Loss | 44.46 μM |
TOX21_p450_CYP3A4_Antagonist | | 1576 | CYP3A4 | P08684 | Loss | 24.10 μM |
TOX21_p450_CYP2C9_Antagonist | | 1559 | CYP2C9 | P11712 | Loss | 27.84 μM |
No ToxCast endpoints for intended target type: Molecular Messengers
No ToxCast endpoints for intended target type: Pathway
No ToxCast endpoints for intended target type: Cellular
No ToxCast endpoints for intended target type: Extracellular