For more information regarding the endpoints, refer to the 'ToxCast Endpoints' file on the
DOWNLOAD page.
No ToxCast endpoints for intended target type: RNA
ToxCast Endpoints for intended target type: Protein
Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
---|
TOX21_CAR_LUC_Agonist | Liver | 9970 | NR1I3 | Q14994 | Gain | 31.51 μM |
TOX21_ERR_LUC_Agonist | Kidney | 2101 | ESRRA | P11474 | Gain | 47.78 μM |
TOX21_PXR_LUC_Agonist | Liver | 8856 | NR1I2 | O75469 | Gain | 34.57 μM |
TOX21_p450_CYP2D6_Antagonist | | 1565 | CYP2D6 | P10635 | Loss | 58.81 μM |
No ToxCast endpoints for intended target type: Molecular Messengers
No ToxCast endpoints for intended target type: Pathway
No ToxCast endpoints for intended target type: Cellular
No ToxCast endpoints for intended target type: Extracellular