Biomolecule details
Biomolecule TypeGene
Collected Gene NameHMGCR
Official Gene SymbolHmgcr
Organism-specific Database IDRGD:2803
Official Gene Name3-hydroxy-3-methylglutaryl-CoA reductase
Ensembl IDENSRNOG00000016122
NCBI Gene ID25675
Organism MappedRat

Tested organism details
Organism TestedRattus norvegicus
Ethnicity/StrainSprague-Dawley
GenderFemale
Age (years)0.12

Tested cell details
Tested Cell/Tissue Name (collected)Lenses
Exposed AreaEye
Exposed Area TypeTissue
Ontology Termtransparent eye structure
Ontology IdentifierUBERON_0005389
Ontology Identifier TypeUberon Ontology

UV details
UV TypeUVB-radiation
Dose (J/m2)40500000
Dosage Rate (W/m2)1.5


Experiment Information
Study Typein vivo
ControlNo irradiation
Omics TypeGenomics
Testing Methodsemiquantitative real-time PCR
RegulationUp
PMID
31555133
DISCLAIMER

UVREK stands as a comprehensive knowledgebase, encompassing biomolecules implicated in UV exposure across humans and rodents. The data within this repository has been meticulously gathered and curated from published research articles. It is imperative to note that we bear no liability for inaccuracies or omissions within the data or published scientific literature associated with UV exposure in this resource. Users are advised to exercise personal discretion when assessing the credibility of biomolecules compiled herein. Crucially, the establishment of this resource, focused on UV-affected biomolecules, is driven by the sole goal of facilitating future basic research endeavors to better understand systems-level perturbations. It is essential to underscore that the content herein does not necessarily mirror the views or objectives of our employers or funders.