Biomolecule details
Biomolecule TypeGene
Collected Gene NameHSD11B2
Official Gene SymbolHSD11B2
Organism-specific Database IDHGNC:5209
Official Gene Namehydroxysteroid 11-beta dehydrogenase 2
Ensembl IDENSG00000176387
NCBI Gene ID3291
Organism MappedHuman

Tested organism details
Organism TestedHomo sapiens

Tested cell details
Tested Cell/Tissue Name (collected)Co-culture of human epidermal neonatal keratinocytes (HEKn) and human epidermal neonatal melanocytes (HEMn)
Exposed AreaCo-culture of human epidermal neonatal keratinocytes (HEKn) and human epidermal neonatal melanocytes (HEMn)
Exposed Area TypeCell
Ontology Termkeratinocyte;melanocyte
Ontology IdentifierCL_0000312;CL_0000148
Ontology Identifier TypeCell Ontology

UV details
UV TypeUVB-radiation
Dose (J/m2)500


Experiment Information
Study TypeIn vitro
ControlNo irradiation
Sampling Time (hrs)12
Omics TypeGenomics
Testing MethodqRT-PCR
RegulationUp
PMID
23363016
DISCLAIMER

UVREK stands as a comprehensive knowledgebase, encompassing biomolecules implicated in UV exposure across humans and rodents. The data within this repository has been meticulously gathered and curated from published research articles. It is imperative to note that we bear no liability for inaccuracies or omissions within the data or published scientific literature associated with UV exposure in this resource. Users are advised to exercise personal discretion when assessing the credibility of biomolecules compiled herein. Crucially, the establishment of this resource, focused on UV-affected biomolecules, is driven by the sole goal of facilitating future basic research endeavors to better understand systems-level perturbations. It is essential to underscore that the content herein does not necessarily mirror the views or objectives of our employers or funders.