Biomolecule details
Biomolecule TypeMetabolite
Collected Metabolite Name8-Isoprostane
KEGG IDC13809
Official Metabolite name9,11,15-Trihydroxy-prosta-5,13-dien-1-oic acid
Synonyms8-Isoprostaglandin F2alpha;8-Isoprostane;8-epi-Prostaglandin F2alpha
CAS ID27415-26-5
PubChem ID5282263
ChEBICHEBI:34505

Tested organism details
Organism TestedHomo sapiens

Tested cell details
Tested Cell/Tissue Name (collected)Reconstructed 3D human corneal epithelial (3D-HCE) tissue
Exposed Area TypeTissue
Ontology Termcorneal epithelium
Ontology IdentifierUBERON_0001772
Ontology Identifier TypeUberon Ontology

UV details
UV TypeUVB-radiation
Dose (J/m2)600


Experiment Information
Study Typein vitro
ControlNo irradiation
Sampling Time (hrs)24
Omics TypeMetabolomics
Testing Method8-Isoprostane competitive EIA (enzyme immuno assay) assay kit
RegulationUp
PMID
31705899
DISCLAIMER

UVREK stands as a comprehensive knowledgebase, encompassing biomolecules implicated in UV exposure across humans and rodents. The data within this repository has been meticulously gathered and curated from published research articles. It is imperative to note that we bear no liability for inaccuracies or omissions within the data or published scientific literature associated with UV exposure in this resource. Users are advised to exercise personal discretion when assessing the credibility of biomolecules compiled herein. Crucially, the establishment of this resource, focused on UV-affected biomolecules, is driven by the sole goal of facilitating future basic research endeavors to better understand systems-level perturbations. It is essential to underscore that the content herein does not necessarily mirror the views or objectives of our employers or funders.