Biomolecule details
Biomolecule TypeMetabolite
Collected Metabolite Name8-isoprostanes
KEGG IDC13809
Official Metabolite name9,11,15-Trihydroxy-prosta-5,13-dien-1-oic acid
Synonyms8-Isoprostaglandin F2alpha;8-Isoprostane;8-epi-Prostaglandin F2alpha
CAS ID27415-26-5
PubChem ID5282263
ChEBICHEBI:34505

Tested organism details
Organism TestedHomo sapiens
Ethnicity/StrainHealthy
GenderBoth

Tested cell details
Tested Cell/Tissue Name (collected)keratinocyte
Exposed AreaSkin
Exposed Area TypeCell
Ontology Termkeratinocyte
Ontology IdentifierCL_0000312
Ontology Identifier TypeCell Ontology

UV details
UV TypeUVA-radiation
Dose (J/m2)300000
Dosage Rate (W/m2)42


Experiment Information
Study Typein vitro
ControlNo irradiation
Omics TypeMetabolomics
Testing Methodultra-performing liquid chromatography tandem mass spectrometry
RegulationUp
PMID
32121131
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UVREK stands as a comprehensive knowledgebase, encompassing biomolecules implicated in UV exposure across humans and rodents. The data within this repository has been meticulously gathered and curated from published research articles. It is imperative to note that we bear no liability for inaccuracies or omissions within the data or published scientific literature associated with UV exposure in this resource. Users are advised to exercise personal discretion when assessing the credibility of biomolecules compiled herein. Crucially, the establishment of this resource, focused on UV-affected biomolecules, is driven by the sole goal of facilitating future basic research endeavors to better understand systems-level perturbations. It is essential to underscore that the content herein does not necessarily mirror the views or objectives of our employers or funders.