Biomolecule details
Biomolecule TypeProtein
Collected Protein NameTIMP-1
UniProt NameTIMP1_HUMAN
UniProt IDP01033
Official Gene SymbolTIMP1
Organism-specific Database IDHGNC:11820
Official Protein NameMetalloproteinase inhibitor 1
Organism MappedHuman

Tested organism details
Organism TestedHomo sapiens
Ethnicity/StrainHealthy
GenderBoth

Tested cell details
Tested Cell/Tissue Name (collected)Neonatal human dermal fibroblast cell line (NHDF)
Exposed Area TypeCell
Ontology Termfibroblast of dermis
Ontology IdentifierCL_0002551
Ontology Identifier TypeCell Ontology

UV details
UV TypeUVB-radiation
Dose (J/m2)300


Experiment Information
Study Typein vitro
ControlNo irradiation
Sampling Time (hrs)48
Omics TypeProteomics
Testing MethodWestern blot
RegulationUp
PMID
31432192
DISCLAIMER

UVREK stands as a comprehensive knowledgebase, encompassing biomolecules implicated in UV exposure across humans and rodents. The data within this repository has been meticulously gathered and curated from published research articles. It is imperative to note that we bear no liability for inaccuracies or omissions within the data or published scientific literature associated with UV exposure in this resource. Users are advised to exercise personal discretion when assessing the credibility of biomolecules compiled herein. Crucially, the establishment of this resource, focused on UV-affected biomolecules, is driven by the sole goal of facilitating future basic research endeavors to better understand systems-level perturbations. It is essential to underscore that the content herein does not necessarily mirror the views or objectives of our employers or funders.