Biomolecule details
Biomolecule TypeProtein
Collected Protein NameBcl-2
UniProt NameBCL2_HUMAN
UniProt IDP10415
Official Gene SymbolBCL2
Organism-specific Database IDHGNC:990
Official Protein NameApoptosis regulator Bcl-2
Organism MappedHuman

Tested organism details
Organism TestedHomo sapiens
Age (years)19-51

Tested cell details
Tested Cell/Tissue Name (collected)Biopsy of exposed skin
Exposed AreaTotal body irradiation excluding genital area for 10 days; Left buttock area
Exposed Area TypeTissue
Ontology Termskin of body
Ontology IdentifierUBERON_0002097
Ontology Identifier TypeUberon Ontology

UV details
UV TypeUVB-radiation


Experiment Information
Study TypeIn vivo
ControlNo irradiation
Sampling Time (hrs)24
Omics TypeProteomics
Testing MethodFlow cytometry
RegulationDown
PMID
19221257
DISCLAIMER

UVREK stands as a comprehensive knowledgebase, encompassing biomolecules implicated in UV exposure across humans and rodents. The data within this repository has been meticulously gathered and curated from published research articles. It is imperative to note that we bear no liability for inaccuracies or omissions within the data or published scientific literature associated with UV exposure in this resource. Users are advised to exercise personal discretion when assessing the credibility of biomolecules compiled herein. Crucially, the establishment of this resource, focused on UV-affected biomolecules, is driven by the sole goal of facilitating future basic research endeavors to better understand systems-level perturbations. It is essential to underscore that the content herein does not necessarily mirror the views or objectives of our employers or funders.