Biomolecule details
Biomolecule TypeProtein
Collected Protein NameSREBP-1
UniProt NameSRBP1_HUMAN
UniProt IDP36956
Official Gene SymbolSREBF1
Organism-specific Database IDHGNC:11289
Official Protein NameSterol regulatory element-binding protein 1
Organism MappedHuman

Tested organism details
Organism TestedHomo sapiens

Tested cell details
Tested Cell/Tissue Name (collected)Normal human epidermal keratinocytes (NHEKs)
Exposed Area TypeCell
Ontology Termkeratinocyte
Ontology IdentifierCL_0000312
Ontology Identifier TypeCell Ontology

UV details
UV TypeUVB-radiation
Dose (J/m2)200


Experiment Information
Study Typein vitro
ControlNo irradiation
Sampling Time (hrs)24
Omics TypeProteomics
Testing MethodWestern blot
RegulationDown
PMID
32080341
DISCLAIMER

UVREK stands as a comprehensive knowledgebase, encompassing biomolecules implicated in UV exposure across humans and rodents. The data within this repository has been meticulously gathered and curated from published research articles. It is imperative to note that we bear no liability for inaccuracies or omissions within the data or published scientific literature associated with UV exposure in this resource. Users are advised to exercise personal discretion when assessing the credibility of biomolecules compiled herein. Crucially, the establishment of this resource, focused on UV-affected biomolecules, is driven by the sole goal of facilitating future basic research endeavors to better understand systems-level perturbations. It is essential to underscore that the content herein does not necessarily mirror the views or objectives of our employers or funders.