Biomolecule details
Biomolecule TypeProtein
Collected Protein NameSIRT1
UniProt NameSIR1_MOUSE
UniProt IDQ923E4
Official Gene SymbolSirt1
Organism-specific Database IDMGI:2135607
Official Protein NameNAD-dependent protein deacetylase sirtuin-1
Organism MappedMouse

Tested organism details
Organism TestedMus musculus
Ethnicity/Strain129/SV

Tested cell details
Tested Cell/Tissue Name (collected)Murine skin fibroblasts (strain 129/SV)
Exposed Area TypeCell
Ontology Termfibroblast of dermis
Ontology IdentifierCL_0002551
Ontology Identifier TypeCell Ontology

UV details
UV TypeUVA-radiation
Dose (J/m2)300000


Experiment Information
Study Typein vitro
ControlNo irradiation
Omics TypeProteomics
Testing MethodWestern blot
RegulationDown
PMID
33670907
DISCLAIMER

UVREK stands as a comprehensive knowledgebase, encompassing biomolecules implicated in UV exposure across humans and rodents. The data within this repository has been meticulously gathered and curated from published research articles. It is imperative to note that we bear no liability for inaccuracies or omissions within the data or published scientific literature associated with UV exposure in this resource. Users are advised to exercise personal discretion when assessing the credibility of biomolecules compiled herein. Crucially, the establishment of this resource, focused on UV-affected biomolecules, is driven by the sole goal of facilitating future basic research endeavors to better understand systems-level perturbations. It is essential to underscore that the content herein does not necessarily mirror the views or objectives of our employers or funders.