Intermediates
Number of EDCs: 194
Chemical nameChemical identifierLiterature identifier
4-Hydroxybenzoic acidDED000001PMID:9417843
AcetaldehydeDED000002PMID:22538484, PMID:6723515, PMID:7128453
BenzeneDED000003DOI:10.3109/10915818909018060, PMID:33502539
OctaneDED000004PMID:7423533
PhloroglucinolDED000005PMID:14925120
p-AminophenolDED000006PMID:18850357, PMID:2606405
PropionaldehydeDED000007PMID:4035593
EthanolDED000009PMID:21432428, PMID:21463340, PMID:2318350, PMID:37994192, PMID:611632
FormaldehydeDED000010PMID:12916763
IodineDED000013PMID:28205391
MethanolDED000014PMID:12490131, PMID:9241670
p-NitrophenolDED000017PMID:16884752, PMID:19404784, PMID:24070737, PMID:27172127, PMID:27235926
CaffeineDED000036PMID:23590819, PMID:3607108, PMID:36555195
p-CresolDED000039PMID:12209177
Indole-3-carbinolDED000058PMID:12383709
PhloretinDED000074PMID:24487097
Tetramethylthiuram disulfideDED000083PMID:12606370, PMID:8318751, PMID:8725639
ChloroformDED000101PMID:15758249
DichloromethaneDED000108PMID:6701900, PMID:9804871
Ethylene oxideDED000110PMID:2815085
Trichloroacetic acidDED000113PMID:29294279, PMID:38266585
Acetyl tributyl citrateDED000114PMID:28235592, PMID:35567983
IsopreneDED000118PMID:7923161
Tetrabromobisphenol ADED000121PMID:15635150, PMID:18255212, PMID:18313098, PMID:20399831, PMID:25146423, PMID:25223798, PMID:26253174, PMID:26979758, PMID:28564613, PMID:28616630, PMID:32416200, PMID:33099281, PMID:35101577, PMID:35321852, PMID:36499108, PMID:37487893, PMID:38128231, PMID:38763426, PMID:38997027, PMID:39134236, PMID:39236844
ThymolDED000136PMID:23037998
3-Chloro-1,2-dihydroxypropaneDED000144PMID:6612740, PMID:7663078
ButylphenDED000146PMID:17904329, PMID:8593856
Terephthalic acidDED000151PMID:26289545
1,4-CyclohexanedimethanolDED000159PMID:26289545
EpichlorohydrinDED000162PMID:2258022, PMID:2767356, PMID:4833816, PMID:6612740
Vinyl acetateDED000165PMID:6845374
Ethylene glycol monomethyl etherDED000167PMID:1288759, PMID:4065311, PMID:6499822
TetrahydrofuranDED000168PMID:1601226, PMID:2318358
HexaneDED000170PMID:26410608, PMID:2764718
Ethylene glycol monobutyl etherDED000173PMID:12571679
NonaneDED000174PMID:19152832, PMID:7423533
PropyleneDED000175PMID:12748682
2,4-DichlorophenolDED000183PMID:16641544, PMID:22155427, PMID:33928643, PMID:37888694
ThiocyanateDED000192PMID:18355748, PMID:20479570
NoramidopyrineDED000200PMID:29289696
MedroxyprogesteroneDED000201PMID:14751673, PMID:6458924
OctamethylcyclotetrasiloxaneDED000205PMID:11509742, PMID:17418525, PMID:34884750
DibutyldichlorotinDED000215PMID:2466803
t-Butyl methyl etherDED000233PMID:10746943, PMID:10966521, PMID:19344668, PMID:19595749, PMID:35131586
2,4,2',4'-TetranitrobiphenylDED000237PMID:28430429
1,2,5,6,9,10-HexabromocyclododecaneDED000252PMID:15585367
Sodium silicateDED000264PMID:4346985
ChromiumDED000268PMID:23470461, PMID:28911802
1,2,4-Trichlorodibenzo-1,4-dioxinDED000319PMID:1949037
Dibenzo(b,e)(1,4)dioxin, 2,3-dibromo-7,8-dichloro-DED000327DOI:10.1016/0045-6535(91)90040-K
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxideDED000333PMID:29144987, PMID:34050522, PMID:37167865, PMID:37802009
2-Hydroxybenzo(a)pyreneDED000336PMID:626971
2,2',4,4',5,5'-Hexachlorodiphenyl etherDED000347PMID:9177011
2,3,5,6-TetrachlorohydroquinoneDED000359PMID:1949037, PMID:2017761
2,2-Bis(4-hydroxyphenyl)-1,1,1-trichloroethaneDED000371PMID:22549810
4,4'-DiiodobiphenylDED000372PMID:15585367
2,3',4',6-Tetrachlorodiphenyl etherDED000382PMID:9177011
EquolDED000389PMID:18656497, PMID:23220561, PMID:24211351
2,2',4,5,6'-Pentachlorodiphenyl etherDED000397PMID:9177011
3,3',4,4',5,5'-HexabromobiphenylDED000400DOI:10.3109/10915818209018016, PMID:17447562
4-Hydroxy-2',4',6'-trichlorobiphenylDED000401PMID:8318755
1,1'-Biphenyl, 2,2',4',5,5'-pentachloro-3-(methylsulfonyl)-DED000404PMID:10330683, PMID:10739067, PMID:18025052
2,3',4,4'5,5'-HexabromobiphenylDED000407DOI:10.3109/10915818209018016
1,1'-Biphenyl, 2,2',3,4,5'-pentachloro-3'-(methylsulfonyl)-DED000408PMID:10739067
1,1'-Biphenyl, 2,2',4,5,5'-pentachloro-4'-(methylsulfonyl)-DED000409PMID:10330683, PMID:10739067, PMID:18025052
1,1'-Biphenyl, 2,2',3,4,5'-pentachloro-4'-(methylsulfonyl)-DED000410PMID:10330683, PMID:10739067
Dibenzo(b,e)(1,4)dioxin, 2-bromo-3,7,8-trichloro-DED000413DOI:10.1016/0045-6535(91)90040-K
1,1'-Biphenyl, 2,2',3,4,5,5'-hexachloro-3'-(methylsulfonyl)-DED000415PMID:10739067, PMID:9765071
1-Chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzeneDED000419PMID:11869873, PMID:1591480, PMID:19900470, PMID:2055367, PMID:7579910
1,1'-Biphenyl, 2,2',3,4',5',6-hexachloro-4-(methylsulfonyl)-DED000420PMID:10739067, PMID:16216300, PMID:9765071
1,1'-Biphenyl, 2,2',3,3',4',6-hexachloro-5-(methylsulfonyl)-DED000421PMID:10739067, PMID:9765071
1,1'-Biphenyl, 2,2',4',5-tetrachloro-3-(methylsulfonyl)-DED000422PMID:10330683, PMID:10739067
EscitalopramDED000425PMID:28179152
3-Methylsulfonyl-2,3',4',5-tetrachlorobiphenylDED000426PMID:10330683, PMID:10739067
1,1'-Biphenyl, 2,2',3,4',5',6-hexachloro-5-(methylsulfonyl)-DED000427PMID:10739067, PMID:16216300, PMID:9765071
Oxanthrene, 2,3,7-tribromo-8-chloro-DED000432DOI:10.1016/0045-6535(91)90040-K
Beta-SitosterolDED000435PMID:10825674, PMID:15597897
2-ButenalDED000449PMID:16442836
HydroxytamoxifenDED000450PMID:15315699
CinnamaldehydeDED000454PMID:2606408, PMID:7813982
3,3-dibromobisphenol ADED000456PMID:11693576
3-monobromobisphenol ADED000457PMID:11693576
2,2-bis(4-hydroxyphenyl)-propanolDED000458PMID:9449681
3,3-bis(4-hydroxyphenyl)pentaneDED000462PMID:9449681
3,5-Dibromo-2-(2,4-dibromophenoxy)phenolDED000477PMID:16177243, PMID:18022659, PMID:20549613
4,4'-Propane-1,1-diyldiphenolDED000480PMID:9449681
QuercetinDED000482PMID:22121774, PMID:23836117, PMID:24447974
Biochanin ADED000483PMID:12153753, PMID:36555195
FormononetinDED000484PMID:12153753
LuteolinDED000485PMID:23836117
3-MethylquercetinDED000488PMID:14706564
MyricetinDED000489PMID:24487097
CoumestrolDED000490PMID:10828501, PMID:17683461
9,10-dihydroxy-12-octadecenoic acidDED000492PMID:16330350
Amsonic acidDED000494PMID:1316972
LeadDED000504PMID:12220594, PMID:1909817, PMID:22806249, PMID:25434758, PMID:35104782, PMID:37659646, PMID:7444965, PMID:8199261, PMID:8619245, PMID:8989890
BoronDED000509PMID:23213697
1H-Benzimidazole, 5-methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2- pyridinyl)methyl)sulfinyl)-DED000519PMID:27002602
1,2-Diphenylcyclobutane, trans-DED000532PMID:11485868
2-OH-BDE-123DED000534PMID:18313098
2,3',4',6-Tetrabromodiphenyl etherDED000539PMID:11861977, PMID:14999130, PMID:18313098, PMID:18470304, PMID:22127959, PMID:25060363, PMID:28644858, PMID:8134923
Sodium nitriteDED000547PMID:2807101, PMID:3352650, PMID:9207897
Ascorbic acidDED000555PMID:23590819
MonophenyltinDED000566PMID:25465476
AcetaminophenDED000573PMID:23590819, PMID:23670170, PMID:24298046, PMID:26259604, PMID:29665328, PMID:31305161, PMID:32221642, PMID:33098425, PMID:35147701, PMID:35259261, PMID:38657942
Benzo(a)pyreneDED000576PMID:18634860, PMID:21737371, PMID:22960446, PMID:23037998, PMID:23059060, PMID:23280776, PMID:24769007, PMID:27221463, PMID:28043741, PMID:28263535, PMID:29649501, PMID:30443902, PMID:31085209, PMID:32023792, PMID:32670863, PMID:33254415, PMID:33297042, PMID:33433340, PMID:33513405, PMID:34050522, PMID:34459573, PMID:35912572, PMID:36460192, PMID:37167865, PMID:37369342, PMID:37783996, PMID:37802009, PMID:38583661, PMID:38701656, PMID:38763096, PMID:39108652, PMID:39226951, PMID:39454710
Dibutyl phthalateDED000581PMID:10641015, PMID:15518916, PMID:15620428, PMID:15883486, PMID:16493179, PMID:17379376, PMID:17654256, PMID:17725530, PMID:19533667, PMID:19903717, PMID:21657945, PMID:21841806, PMID:22179484, PMID:22238399, PMID:23314658, PMID:23536518, PMID:23766129, PMID:25016925, PMID:25614580, PMID:25697569, PMID:25765776, PMID:26948521, PMID:27943041, PMID:28104404, PMID:28641505, PMID:28823096, PMID:28898977, PMID:28918339, PMID:29064414, PMID:29137315, PMID:29969652, PMID:30031264, PMID:30391722, PMID:30940548, PMID:31158667, PMID:31318015, PMID:31387634, PMID:31979393, PMID:32292708, PMID:32334352, PMID:32388187, PMID:32497820, PMID:32810643, PMID:33004990, PMID:33086118, PMID:33920546, PMID:33983380, PMID:34015706, PMID:34088158, PMID:34097988, PMID:34280466, PMID:34395617, PMID:34474386, PMID:34488563, PMID:34793900, PMID:34864161, PMID:35567983, PMID:35605887, PMID:35919841, PMID:35955852, PMID:36215882, PMID:36230992, PMID:36308879, PMID:37167869, PMID:37237912, PMID:37277016, PMID:37762641, PMID:37977363, PMID:38246300, PMID:39262327, PMID:39560046
TrichloroethyleneDED000595PMID:10773841, PMID:12759095, PMID:29294279
TributylchlorostannaneDED000623PMID:12083789, PMID:12773765, PMID:14667468, PMID:16513093, PMID:16613991, PMID:18246498, PMID:20052771, PMID:22362710, PMID:22972585, PMID:23523586, PMID:23913619, PMID:2466803, PMID:24895210, PMID:25101840, PMID:25819109, PMID:25898838, PMID:27267847, PMID:27521499, PMID:28161095, PMID:28781899, PMID:30831249, PMID:31821856, PMID:31927052, PMID:32783468, PMID:36858099, PMID:37406193, PMID:38621455, PMID:7900160
Nickel sulfateDED000630PMID:31392545, PMID:9494062
Ammonium chlorideDED000635PMID:10550527, PMID:31572187
TetrachloroethyleneDED000636PMID:12759095, PMID:17066414, PMID:31310931, PMID:7251397, PMID:8427017
Perfluoro-1-iodohexaneDED000646PMID:21990342, PMID:29665550
Phenol, 4,4'-(1,1-dimethyl-3-methylene-1,3-propanediyl)bis-DED000653PMID:20435109, PMID:30552153
4-hydroxy-2,3,3,4,5-pentachlorobiphenylDED000659PMID:15310862, PMID:18025052, PMID:29788408
4,4'-CyclohexylidenebisphenolDED000662PMID:17904329, PMID:31388671, PMID:32387340, PMID:33753083, PMID:37939739
Diisononyl phthalateDED000667PMID:11099647, PMID:14580783, PMID:15013064, PMID:16493179, PMID:17654256, PMID:20077217, PMID:21075200, PMID:21633115, PMID:22813627, PMID:28300662, PMID:28893586, PMID:30649530, PMID:31904422, PMID:32165126, PMID:33223173, PMID:33391822, PMID:33983380, PMID:36929940, PMID:37482143, PMID:38926453
ApigeninDED000671PMID:22414680, PMID:24487097, PMID:30678243
4-hydroxy-2,2,3,4-tetrabromodiphenyl etherDED000684PMID:28299817, PMID:29357290
ClotrimazoleDED000688PMID:31330226, PMID:33910022
LamotrigineDED000692PMID:29718108, PMID:37505509
Vinyl chlorideDED000695PMID:4092642
1,2-Propylene oxideDED000696PMID:12748685, PMID:17179639, PMID:6648426
Toluene-2,4-diamineDED000700PMID:3199457, PMID:3937900, PMID:4093994
1,2,3-TrichloropropaneDED000701PMID:12692652, PMID:3184199
4-NitroanilineDED000702PMID:2258023
Bis(4-aminophenyl) etherDED000704PMID:3881621, PMID:716159
N-MethyldiethanolamineDED000705PMID:31310931
4-XyleneDED000706PMID:7233451
4-ChloroanilineDED000707PMID:12704433
1,3-ButadieneDED000708PMID:2401271, PMID:3591659
AcrylonitrileDED000709PMID:12044704, PMID:18293209, PMID:3388448, PMID:6777907
FuranDED000710PMID:31108444, PMID:31121209, PMID:32174189
DiolamineDED000711PMID:31310931
Methylenedianiline dihydrochlorideDED000730PMID:12750745, PMID:3712494, PMID:4293143
2-Ethyl-5-carboxypentyl phthalateDED000756PMID:30847963
NaproxenDED000758PMID:29655108
Sodium sulfideDED000764PMID:31572187
Zinc dibutyldithiocarbamateDED000772PMID:689578
Dibutyltin dilaurateDED000777PMID:2899427
CatecholDED000794PMID:36241036, PMID:39512757
Chloroacetic AcidDED000795PMID:36963690
O-CresolDED000796PMID:39512757
6-Formylindolo(3,2-b)carbazoleDED000802PMID:32947662
Methyl SalicylateDED000817PMID:39454092
4-ChlorophenolDED000820PMID:36241036
1,1',1''-(Chlorosilylidyne)tris(benzene)DED000832PMID:31927052
2-BromophenolDED000845PMID:36241036
2,4-Di-tert-butylphenolDED000846PMID:36750942
1,2-DibromoethaneDED000847PMID:9804871
Ethyl SalicylateDED000852PMID:39454092
ChloranilDED000853PMID:38555059
Diallyl phthalateDED000855PMID:33983380
CyanamideDED000859PMID:33892370
DecamethylcyclopentasiloxaneDED000860PMID:37112528, PMID:37551828
4-HexylphenolDED000875PMID:38997027
Aluminum ChlorideDED000883PMID:32485499, PMID:34726835, PMID:34958889, PMID:36695414
Sodium NitrateDED000885PMID:34409734
Nickel DichlorideDED000886PMID:32901497
3,5-DichlorocatecholDED000889PMID:39512757
4-AminoacetanilideDED000893PMID:34014586
3-FluorocatecholDED000909PMID:39512757
3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-olDED000914PMID:38535903
Phenol, 4,4'-(1-methylethylidene)bis(2-(2-propen-1-yl)-DED000918PMID:38128231
1,1,1-Tris(4-hydroxyphenyl)ethaneDED000934PMID:32004960
Benzene, 2,4-dimethoxy-1-methyl-DED000935PMID:39512757
4-AminocatecholDED000942PMID:39512757
4-Fluoro-1,2-benzenediolDED000945PMID:39512757
Bis(1,3-dichloro-2-propyl) phosphateDED000949PMID:32150676
CatecholamineDED000950PMID:39512757
Bis(4-hydroxyphenyl)diphenylmethaneDED000953PMID:32508751, PMID:37816402
3-BromocarbazoleDED000955PMID:32344252, PMID:36522090
1,3,6,8-TetrabromocarbazoleDED000956PMID:32344252
4,4'-(9-Fluorenylidene)dianilineDED000966PMID:36270036
N-(2,3-dimethylphenyl)-2-morpholin-4-ylacetamideDED000968PMID:38040386, PMID:38360075
9-(nonafluorobutyl)-2,3,6,7-tetrahydro-1H,5H,11H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-11-oneDED000973PMID:35093747
4-NitrocatecholDED000983PMID:39512757
9,9-Bis[4-(2-hydroxyethoxy)phenyl]fluoreneDED000984PMID:35878500
1H,1H,8H,8H-Perfluorooctane-1,8-diolDED000986PMID:38535903
4,4'-(3,3,5-Trimethylcyclohexylidene)bis(phenol)DED000988PMID:39520287
2,7-DibromocarbazoleDED001005PMID:32344252, PMID:36522090
CyantraniliproleDED001008PMID:34968715
2-Bromo-9H-carbazoleDED001014PMID:32344252, PMID:36522090
5-(1,2,2,2-Tetrafluoro)ethoxy-perfluoro-3-oxa-4-methylpentanesulfonic acidDED001016PMID:38535903
1,2,9,10-TetrachlorodecaneDED001018PMID:38331103
Mono-3-hydroxybutyl phthalateDED001020PMID:35567983
2-(3-Chloro-4-hydroxyphenyl)-2-(4-hydroxyphenyl)propaneDED001021PMID:38128231
1,2-DichlorotetradecaneDED001023PMID:38331103
Chloro(iodo)acetic acidDED001025PMID:36963690
Bisphenol A monosulfateDED001031PMID:35041905
2-[(Dimethoxyphosphoryl)sulfanyl]butanedioic acidDED001033PMID:32007685
Monocarboxy isononyl phthalateDED001039PMID:35567983
2-(6-Hydroxy-2-propylheptoxy)carbonylbenzoic acidDED001040PMID:35567983
1,2-Cyclohexanedicarboxylic Acid Mono 4-Methyloctyl EsterDED001042PMID:35567983
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.