Batch Download
S. No.File descriptionFile typeFile sizeDownload
1Names and Identifiers of EDCs
List of 686 EDCs with their PubChem identifier, CAS Number, Name, IUPAC Name, SMILES, InChI and InChIKey.
csv175K
2Classification and Categorization of EDCs
List of 686 EDCs with their Chemical Kingdom, Chemical Superclass, Chemical Class, Chemical Subclass, Broad category based on their Environmental Source and Sub-category based on their Environmentak Source.
csv138K
3 Literature evidence, Dosage Information, Endpoint and Systems-level endocrine-mediated perturbations of EDCs
List of 686 EDCs with their Literature evidence, Study type, Dosage unit, Test/Effective dosage, Endocrine-mediated endpoints and Systems-level perturbations.
csv1.6M
4Physicochemical properties of EDCs
List of 686 EDCs with their Physicochemical properties, namely, Molecular weight, Log P, TPSA, Hydrogen bond acceptors, Hydrogen bond donors, Carbon atoms, Heavy atoms, Heteroatoms, Chiral centers and Rotatable bonds.
csv31K
5Predicted ADMET properties of EDCs
List of 686 EDCs with their predicted ADMET (Absorption, Distribution, Metabolism and Toxicity) properties.
csv1.2M
6Chemical Gene Interaction of EDCs
List of 383 EDCs with their target genes along with their corresponding ToxCast assay component endpoint name obtained from ToxCast.
csv814K
7Predicted Molecular Descriptors of EDCs
List of 686 EDCs with their predicted 1D, 2D and 3D Molecular descriptors computed using Padel, Pybel and RDkit.
csv167M
82D structure of EDCs
A single sdf file with 2-dimensional structure of 686 EDCs.
sdf3.2M
93D structure of EDCs
A single sdf file with 3-dimensional structure of 686 EDCs.
sdf3.2M

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.