Genistein

Target genes for Genistein is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
GenisteinNR1H3ATG_LXRa_TRANS_up
GenisteinNR1H3ATG_DR4_LXR_CIS_up
GenisteinNACEETOX_H295R_PROG_dn
GenisteinESR1CEETOX_H295R_TESTO_dn
GenisteinESR1CEETOX_H295R_ESTRONE_up
GenisteinNACEETOX_H295R_ANDR_dn
GenisteinNACEETOX_H295R_TESTO_dn
GenisteinCCL26BSK_4H_Eotaxin3_down
GenisteinCREB3ATG_CRE_CIS_up
GenisteinCEBPBATG_C_EBP_CIS_up
GenisteinADORA1NVS_GPCR_hAdoRA1
GenisteinADORA2ANVS_GPCR_hAdoRA2a
GenisteinCSF1BSK_LPS_MCSF_down
GenisteinCYP2J2NVS_ADME_hCYP2J2
GenisteinDIO1NHEERL_MED_hDIO1_dn
GenisteinAHRTOX21_AhR_LUC_Agonist
GenisteinESR1OT_ER_ERaERa_0480
GenisteinESR1CEETOX_H295R_ESTRONE_up
GenisteinESR1TOX21_ERa_LUC_VM7_Agonist
GenisteinESR1OT_ER_ERaERb_1440
GenisteinESR1OT_ER_ERaERa_1440
GenisteinESR1OT_ERa_EREGFP_0120
GenisteinESR1ATG_ERa_TRANS_up
GenisteinESR1TOX21_ERa_BLA_Antagonist_ratio
GenisteinESR1ATG_ERE_CIS_up
GenisteinESR1TOX21_ERa_BLA_Agonist_ratio
GenisteinESR1OT_ERa_EREGFP_0480
GenisteinESR1NVS_NR_hER
GenisteinESR1OT_ER_ERaERb_0480
GenisteinESR1ACEA_ER_80hr
GenisteinESR2OT_ER_ERbERb_0480
GenisteinESR2OT_ER_ERaERb_1440
GenisteinESR2OT_ER_ERaERb_0480
GenisteinESR2TOX21_ERb_BLA_Agonist_ratio
GenisteinESR2CEETOX_H295R_ESTRONE_up
GenisteinESR2TOX21_ERb_BLA_Antagonist_ratio
GenisteinESR2OT_ER_ERbERb_1440
GenisteinESRRATOX21_PGC_ERR_Agonist
GenisteinESRRATOX21_ERR_Agonist
GenisteinF3BSK_LPS_TissueFactor_down
GenisteinSIRT1NVS_ENZ_hSIRT1
GenisteinNR3C1CEETOX_H295R_DOC_dn
GenisteinNR3C1CEETOX_H295R_11DCORT_dn
GenisteinNR3C1CEETOX_H295R_CORTISOL_dn
GenisteinHDAC1TOX21_HDAC_Inhibition
GenisteinHLA-DRABSK_3C_HLADR_down
GenisteinHLA-DRABSK_CASM3C_HLADR_down
GenisteinIL1ABSK_LPS_IL1a_down
GenisteinIL6BSK_CASM3C_IL6_down
GenisteinCXCL8BSK_SAg_IL8_down
GenisteinCXCL8BSK_CASM3C_IL8_down
GenisteinCXCL8BSK_3C_IL8_down
GenisteinCXCL8BSK_LPS_IL8_down
GenisteinCXCL10BSK_hDFCGF_IP10_up
GenisteinARNVS_NR_hAR
GenisteinARCEETOX_H295R_TESTO_dn
GenisteinARCEETOX_H295R_ANDR_dn
GenisteinARACEA_AR_antagonist_80hr
GenisteinARTOX21_AR_BLA_Antagonist_ratio
GenisteinESR1CEETOX_H295R_TESTO_dn
GenisteinESR1CEETOX_H295R_ESTRONE_up
GenisteinNACEETOX_H295R_TESTO_dn
GenisteinNACEETOX_H295R_ESTRONE_up
GenisteinARCEETOX_H295R_TESTO_dn
GenisteinARCEETOX_H295R_ANDR_dn
GenisteinCXCL9BSK_SAg_MIG_down
GenisteinNR3C2CEETOX_H295R_DOC_dn
GenisteinNR3C2CEETOX_H295R_CORTISOL_dn
GenisteinNR3C2CEETOX_H295R_11DCORT_dn
GenisteinMMP1BSK_hDFCGF_MMP1_down
GenisteinMMP1BSK_BE3C_MMP1_down
GenisteinMMP9BSK_KF3CT_MMP9_down
GenisteinMTF1ATG_MRE_CIS_up
GenisteinNFIAATG_NFI_CIS_up
GenisteinNFE2L2TOX21_ARE_BLA_agonist_ratio
GenisteinNFKB1ATG_NF_kB_CIS_up
GenisteinSERPINE1BSK_hDFCGF_PAI1_down
GenisteinPGRCEETOX_H295R_PROG_dn
GenisteinPGRCEETOX_H295R_OHPREG_up
GenisteinPGRCEETOX_H295R_OHPROG_dn
GenisteinPGRTOX21_PR_BLA_Antagonist_ratio
GenisteinPLATBSK_BE3C_tPA_down
GenisteinPLAUBSK_BE3C_uPA_down
GenisteinPLAURBSK_4H_uPAR_down
GenisteinPLAURBSK_3C_uPAR_down
GenisteinPOU2F1ATG_Oct_MLP_CIS_up
GenisteinPPARAATG_PPARa_TRANS_up
GenisteinPPARAATG_PPRE_CIS_up
GenisteinPPARDATG_PPRE_CIS_up
GenisteinPPARDTOX21_PPARd_BLA_antagonist_ratio
GenisteinPPARGATG_PPRE_CIS_up
GenisteinPPARGTOX21_PPARg_BLA_antagonist_ratio
GenisteinPPARGATG_PPARg_TRANS_up
GenisteinPTGER2BSK_LPS_PGE2_down
GenisteinPTPRBNVS_ENZ_hPTPRB_Activator
GenisteinRXRAOT_NURR1_NURR1RXRa_1440
GenisteinRXRAOT_NURR1_NURR1RXRa_0480
GenisteinRXRBATG_RXRb_TRANS_up
GenisteinSAA1BSK_CASM3C_SAA_up
GenisteinCCL2BSK_SAg_MCP1_down
GenisteinCCL2BSK_LPS_MCP1_down
GenisteinCCL2BSK_3C_MCP1_down
GenisteinCCL2BSK_CASM3C_MCP1_down
GenisteinCCL2BSK_4H_MCP1_down
GenisteinSELEBSK_SAg_Eselectin_down
GenisteinSELEBSK_LPS_Eselectin_down
GenisteinSELPBSK_4H_Pselectin_down
GenisteinSP1ATG_Sp1_CIS_up
GenisteinSREBF1ATG_SREBP_CIS_up
GenisteinTFAP2AATG_AP_2_CIS_dn
GenisteinTFAP2BATG_AP_2_CIS_dn
GenisteinTSPONVS_MP_hPBR
GenisteinTNFBSK_LPS_TNFa_down
GenisteinTP53APR_HepG2_p53Act_24h_up
GenisteinTP53APR_HepG2_p53Act_72h_up
GenisteinNR1H2ATG_DR4_LXR_CIS_up
GenisteinVCAM1BSK_4H_VCAM1_down
GenisteinVCAM1BSK_LPS_VCAM1_down
GenisteinVCAM1BSK_CASM3C_VCAM1_up
GenisteinNACEETOX_H295R_ANDR_dn
GenisteinNACEETOX_H295R_TESTO_dn
GenisteinATAD5TOX21_ELG1_LUC_Agonist
GenisteinTFAP2DATG_AP_2_CIS_dn
GenisteinNR1I2ATG_PXR_TRANS_up
GenisteinCD38BSK_SAg_CD38_down
GenisteinCD40BSK_LPS_CD40_down
GenisteinCD40BSK_SAg_CD40_down
GenisteinCD69BSK_SAg_CD69_down
GenisteinNR1I3TOX21_CAR_Agonist
GenisteinNR1I3ATG_PBREM_CIS_up
GenisteinNR1H4ATG_IR1_CIS_up
GenisteinNR1H4TOX21_FXR_BLA_antagonist_ratio
GenisteinNR1H4OT_FXR_FXRSRC1_0480
GenisteinNR1H4OT_FXR_FXRSRC1_1440

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