Acetyl tributyl citrate

Target genes for Acetyl tributyl citrate is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
Acetyl tributyl citrateNR1H3ATG_DR4_LXR_CIS_dn
Acetyl tributyl citrateCYP2C19NVS_ADME_hCYP2C19
Acetyl tributyl citrateESRRATOX21_ERR_Antagonist
Acetyl tributyl citrateESRRATOX21_PGC_ERR_Antagonist
Acetyl tributyl citrateHIF1AATG_HIF1a_CIS_up
Acetyl tributyl citrateHLA-DRABSK_BE3C_HLADR_down
Acetyl tributyl citrateIRF1ATG_ISRE_CIS_dn
Acetyl tributyl citrateARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
Acetyl tributyl citrateSMAD1ATG_BRE_CIS_up
Acetyl tributyl citrateMMP1BSK_BE3C_MMP1_up
Acetyl tributyl citrateMTF1ATG_MRE_CIS_up
Acetyl tributyl citratePGRTOX21_PR_BLA_Antagonist_ratio
Acetyl tributyl citratePPARAATG_PPRE_CIS_up
Acetyl tributyl citratePPARDATG_PPRE_CIS_up
Acetyl tributyl citratePPARGATG_PPRE_CIS_up
Acetyl tributyl citratePPARGATG_PPARg_TRANS_up
Acetyl tributyl citrateRARBATG_RARb_TRANS_dn
Acetyl tributyl citrateRORAATG_RORE_CIS_up
Acetyl tributyl citrateRORBATG_RORE_CIS_up
Acetyl tributyl citrateRORCATG_RORE_CIS_up
Acetyl tributyl citrateSAA1BSK_CASM3C_SAA_up
Acetyl tributyl citrateTP53APR_HepG2_p53Act_24h_up
Acetyl tributyl citrateTP53APR_HepG2_p53Act_72h_up
Acetyl tributyl citrateTSHRTOX21_TSHR_Antagonist_ratio
Acetyl tributyl citrateNR1H2ATG_DR4_LXR_CIS_dn
Acetyl tributyl citrateVDRATG_VDRE_CIS_up
Acetyl tributyl citrateNR1I2ATG_PXRE_CIS_up
Acetyl tributyl citrateNR1I2ATG_PXR_TRANS_up
Acetyl tributyl citrateCD40BSK_SAg_CD40_down
Acetyl tributyl citrateCD40BSK_LPS_CD40_down
Acetyl tributyl citrateNR1I3NVS_NR_hCAR_Antagonist
Acetyl tributyl citrateNR1I3TOX21_CAR_Agonist
Acetyl tributyl citrateNR1I3ATG_PBREM_CIS_up
Acetyl tributyl citrateNR1H4OT_FXR_FXRSRC1_0480

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.