Category IV: Supporting evidence from only in vitro human experiments
Number of EDCs: 203
Chemical nameChemical identifierLiterature identifier
MonophenyltinCAS:2406-68-0PMID:25465476
3'-Methoxy-4'-nitroflavoneCID:10017512PMID:20823264
8:2 monoalkylated phosphate surfactantsCID:10143739PMID:23142464
Chrysophanic acidCID:10208PMID:11459643
Perfluorooctyl iodideCID:10491PMID:21990342, PMID:25871633
NoramidopyrineCID:10618PMID:29289696
3,3',4,4'-TetrabromobiphenylCID:107953PMID:17447562
2-MeO-BDE-123CID:10908094PMID:18313098
1,2-Diphenylcyclobutane, cis-CID:111326PMID:11485868
PhtppCID:11201035PMID:29495557
FormestaneCID:11273PMID:12153753
Phenol, 4-((4-(phenylmethoxy)phenyl)sulfonyl)-CID:113063PMID:31388671
ThiaclopridCID:115224PMID:28750898
Bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalateCID:117291PMID:24064184
alpha-NaphthoflavoneCID:11790PMID:20823264
Methyl 2-benzoylbenzoateCID:11816PMID:26692070
2,3-Dibromopropyl 2,4,6-tribromophenyl etherCID:118216PMID:25454221, PMID:29556062
Mono(2-ethyl-5-oxohexyl)phthalateCID:119096PMID:30847963
4,4-bis(4-hydroxyphenyl)heptaneCID:11954121PMID:9449681
1,2-Diphenylcyclobutane, trans-CID:11954175PMID:11485868
2-OH-BDE-123CID:11978695PMID:18313098
2,4-Diethyl-9H-thioxanthen-9-oneCID:122825PMID:23208609
Endosulfan IICID:12309460PMID:7925178
AldrinCID:12310947PMID:16996190
(1S)-trans-(Alphar)-cypermethrinCID:12617361PMID:30611075
(S)-LactofenCID:12926729PMID:31524045
Napropamide-MCID:13013865PMID:31524045
2-bromoallyl 2,4,6-tribromophenylether(bate)CID:13643667PMID:25454221
4-Ethyl-1-phospha-2,6,7 trioxabicyclo(2.2.2)octane-1-oxideCID:13869PMID:28430429
1-Aminomethylphosphonic acidCID:14017PMID:31295307
p-ChlorostyreneCID:14085PMID:19654042
EscitalopramCID:146570PMID:28179152
2-Ethyl-5-carboxypentyl phthalateCID:148386PMID:30847963
4-Chloro-2-cresolCID:14855PMID:9828346
m-ChlorostyreneCID:14905PMID:19654042
o-ChlorostyreneCID:14906PMID:19654042
Mono(2-ethylhexyl) terephthalateCID:154683PMID:30847963
NaproxenCID:156391PMID:29655108
Propanoic acid, 2-(4-(2,4-dichlorophenoxy)phenoxy)-, methyl ester, (2S)-CID:156542PMID:31524045
2,4,2',4'-TetranitrobiphenylCID:15757PMID:28430429
4-Isopropyl-9H-thioxanthen-9-oneCID:158403PMID:23208609
t-Butyl hydroquinoneCID:16043PMID:29236469
3,3'-DichlorobiphenylCID:16307PMID:29518658
Ethyl p-nitrophenyl benzenethiophosphonateCID:16421PMID:15253041
Enniatin BCID:164754PMID:25625232
PropisochlorCID:167454PMID:31524045
Tripropyltin chlorideCID:16784PMID:25465476
Mono(2-ethyl-5-hydroxyhexyl) phthalateCID:170295PMID:30847963
CaptafolCID:17038PMID:29953993
ChlorocresolCID:1732PMID:9828346
1,2,5,6,9,10-HexabromocyclododecaneCID:18529PMID:15585367
1,2-Dibromo-4-(1,2-dibromoethyl)cyclohexaneCID:18728PMID:20049203
FenhexamidCID:213031PMID:23052036
AminoglutethimideCID:2145PMID:15187238, PMID:15884376, PMID:16935330, PMID:16962624, PMID:18626888, PMID:20087668
AmpyroneCID:2151PMID:29289696
AnastrozoleCID:2187PMID:12153753
TerbuthylazineCID:22206PMID:27431321
3,3-bis(4-hydroxyphenyl)pentaneCID:2288503PMID:9449681
LilialCID:228987PMID:19338011
6-MeO-BDE-47CID:23249466PMID:20549613
N-(6-Aminopyridin-2-yl)-4'-cyanobiphenyl-4-sulfonamideCID:23725123PMID:30021644
2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroetheneCID:246598PMID:16243481
Cadmium nitrateCID:25154PMID:20197112
2,2'-DichlorobiphenylCID:25622PMID:29518658
Tri-(2-chloroisopropyl)phosphateCID:26176PMID:22446829
NapropamideCID:27189PMID:31524045
CitalopramCID:2771PMID:26162595, PMID:28179152
Tetradecanoylphorbol acetateCID:27924PMID:15187238, PMID:15884376
ClotrimazoleCID:2812PMID:31330226
DanthronCID:2950PMID:11459643
Cyclooctane, 1,2,5,6-tetrabromo-CID:296646PMID:24064184
Bis(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,12-heneicosafluoro-1-dodecanol) hydrogen phosphateCID:3022255PMID:23142464
TributyltinCID:3032732PMID:11097870
Tributyltin bromideCID:305767PMID:16513093
3,5-Dibromo-2-(2,4-dibromophenoxy)phenolCID:3086109PMID:16177243, PMID:18022659, PMID:20549613
AlphamethrinCID:3086172PMID:30611075
Valproic acidCID:3121PMID:19566492, PMID:20726872
Tris(2,3-dibromo-1-propyl) phosphateCID:31356PMID:28430429
Tributyl phosphateCID:31357PMID:26979758
Butylated hydroxytolueneCID:31404PMID:29236469, PMID:31310931
EconazoleCID:3198PMID:20708073
8-Bromo cyclic adenosine monophosphateCID:32014PMID:11675267, PMID:15187238, PMID:15884376
EmodinCID:3220PMID:11459643
FluconazoleCID:3365PMID:31330226
2,6-DichlorostyreneCID:34254PMID:19654042
Rac-[6]-GingerolCID:3473PMID:23590819
2,4'-DichlorobiphenylCID:36982PMID:29518658
IndomethacinCID:3715PMID:23670170
1-Methyl-3-isobutylxanthineCID:3758PMID:12127262
2,3,3',4',6-PentachlorobiphenylCID:38015PMID:16216300, PMID:24675366
2,3,6,2',3',6'-HexachlorobiphenylCID:38024PMID:29124635
LamotrigineCID:3878PMID:29718108
2,2',3,5'-TetrachlorobiphenylCID:38875PMID:24675366
2,2',4,5'-TetrachlorobiphenylCID:38876PMID:24675366
LetrozoleCID:3902PMID:20087668
IsoprothiolaneCID:39681PMID:17904202
Diclofop-methylCID:39985PMID:31524045
DeoxynivalenolCID:40024PMID:22982764
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxideCID:41322PMID:29144987
TriadimenolCID:41368PMID:15253041
MiconazoleCID:4189PMID:20708073, PMID:31330226
4,4'-Propane-1,1-diyldiphenolCID:4201081PMID:9449681
MitotaneCID:4211PMID:28531659, PMID:9168009
CylindrospermopsinCID:42628600PMID:18440200
1,2,7,8-TetrachlorodibenzofuranCID:42844PMID:1332906
Octyl dimethyl 4-aminobenzoic acidCID:42851PMID:11333184
ParoxetineCID:43815PMID:26162595, PMID:28179152
NaringeninCID:439246PMID:12153753, PMID:24586459
PulmatinCID:442731PMID:11459643
EthylketocyclazocineCID:443409PMID:9831078
PatulinCID:4696PMID:24995434
PhenolsulfonphthaleinCID:4766PMID:17235438
PhenothrinCID:4767PMID:10064545, PMID:15118252
FlutolanilCID:47898PMID:17904202
ColforsinCID:47936PMID:12127262, PMID:15187238, PMID:15884376, PMID:16935330, PMID:16962624, PMID:23616146
PropazineCID:4937PMID:10746939, PMID:27431321
Dibenzofuran, 2,3,7,8-tetrabromo-CID:49973PMID:17447562
Biochanin ACID:5280373PMID:12153753
FormononetinCID:5280378PMID:12153753
LuteolinCID:5280445PMID:23836117
BudesonideCID:5281004PMID:23616146
3-MethylquercetinCID:5281654PMID:14706564
CyproteroneCID:5284537PMID:17822730
LevetiracetamCID:5284583PMID:19566492, PMID:20726872
alpha-ZearalenolCID:5284645PMID:21803136, PMID:27401186, PMID:30189007
3-[(3-(2-Carboxyethyl)-4-methylpyrrol-2-YL)methylene]-2-indolinoneCID:5289418PMID:31734698
LovastatinCID:53232PMID:15884376
FluvoxamineCID:5324346PMID:26162595, PMID:28179152
SulfathiazoleCID:5340PMID:20630653
AlternariolCID:5359485PMID:23665424
Mono-n-butyltinCID:54267PMID:29549738
Ascorbic acidCID:54670067PMID:23590819
ChlortetracyclineCID:54675777PMID:20630653
OxytetracyclineCID:54675779PMID:20630653
MifepristoneCID:55245PMID:22414680
ThiamethoxamCID:5821911PMID:28750898
TrichlorfonCID:5853PMID:17329077
CycloheximideCID:6197PMID:7662587
1,2-Dihydroxy-9,10-anthracenedioneCID:6293PMID:11459643
Bisphenol PCID:630355PMID:31388671
2,4,4',6-TetrachlorobiphenylCID:63107PMID:8593856
CyhexatinCID:6327054PMID:25465476
Trichloroacetic acidCID:6421PMID:29294279
Alpha-EndosulfanCID:6433227PMID:7925178, PMID:8593856
beta-ZearalenolCID:6437352PMID:21803136
Lambda-CyhalothrinCID:6440554PMID:18419197, PMID:20097460, PMID:26877835
EtorphineCID:644209PMID:9831078
Di-n-butyltinCID:6484PMID:29549738, PMID:30045567
Acetyl tributyl citrateCID:6505PMID:28235592
Tri-p-cresyl phosphateCID:6529PMID:22446829
Tri(2-butoxyethyl) phosphateCID:6540PMID:22446829
3,3-dibromobisphenol ACID:656687PMID:11693576
3-monobromobisphenol ACID:656688PMID:11693576
2,2-bis(4-hydroxyphenyl)-propanolCID:656692PMID:9449681
p-tert-AmylphenolCID:6643PMID:8593856
EtomidateCID:667484PMID:18626888
Perfluoro-1-iodohexaneCID:67733PMID:21990342, PMID:29665550
Perfluorohexanesulfonic acidCID:67734PMID:23764977
2,6-DihydroxyanthraquinoneCID:6776PMID:11459643
(R)-LactofenCID:67930073PMID:31524045
Butyl glycolyl butyl phthalateCID:6819PMID:12686300
2,4,6-TrichlorophenolCID:6914PMID:21296122, PMID:30609499
2-Phenyl phenolCID:7017PMID:12737316
Hydroxycyclohexyl phenyl ketoneCID:70355PMID:26692070
2-EthylhexyltetrabromobenzoateCID:71316600PMID:24064184
Benzyl p-hydroxybenzoateCID:7180PMID:31388671
6-HydroxyflavoneCID:72279PMID:18626888
3,4-DichloroanilineCID:7257PMID:31100596
4-sec-ButylphenolCID:7453PMID:8593856
Terephthalic acidCID:7489PMID:26289545
2,2-Bis(4-hydroxyphenyl)-1,1,1-trichloroethaneCID:76302PMID:22549810
4,4'-DiiodobiphenylCID:76348PMID:15585367
2,2-di(4-Methacryloxyphenyl)propaneCID:76739PMID:18174953, PMID:8919768, PMID:9449681
1,3,5-Tribromo-2-(prop-2-en-1-yloxy)benzeneCID:76767PMID:25454221
1,4-CyclohexanedimethanolCID:7735PMID:26289545
N-MethyldiethanolamineCID:7767PMID:31310931
1,6-DiiodoperfluorohexaneCID:78994PMID:29665550
2,4'-Dihydroxydiphenyl sulfoneCID:79381PMID:31388671
2-(Propan-2-yl)-9H-thioxanthen-9-oneCID:79633PMID:23208609, PMID:26692070
4,4'-Isopropylidenedi-2,6-xylolCID:79717PMID:28616630, PMID:31388671
DiolamineCID:8113PMID:31310931
2,2,2-TrichloroethanolCID:8259PMID:29294279
DicofolCID:8268PMID:15253041
1,1-Bis(4-hydroxyphenyl)-2,2-dichloroethyleneCID:84677PMID:31388671
4-Hydroxybenzoic acid 3-hydroxybutyl esterCID:85682529PMID:29945225
CaptanCID:8606PMID:29953993
FolpetCID:8607PMID:29953993
3,3',4,5'-Tetrabromodiphenyl etherCID:86208519PMID:18313098
FludioxonilCID:86398PMID:23052036
1-NaphthylamineCID:8640PMID:31100596
PenfenateCID:89040PMID:22119440
7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthaleneCID:89440PMID:23084589
BAY 93820CID:90479PMID:20688129
2,2-Dimethoxy-2-phenylacetophenoneCID:90571PMID:26692070
GalaxolideCID:91497PMID:23084589
HydroxyflutamideCID:91649PMID:29556062
theta-CypermethrinCID:91691PMID:30611075
PenconazoleCID:91693PMID:23811263
2-Methyl-4'-(methylthio)-2-morpholinopropiophenoneCID:92387PMID:26692070
Alpha-CypermethrinCID:93357PMID:30611075
1H-Benzimidazole, 5-methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2- pyridinyl)methyl)sulfinyl)-CID:9568614PMID:27002602
Omeprazole, (R)-CID:9579578PMID:27002602
DieldrinCID:969491PMID:17848404, PMID:7925178
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.